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Deduced Amino Acid Sequence of an Alpha-Gliadin Gene from Spelt Wheat (Spelta) Includes Sequences Active in Celiac Disease

Authors: Kasarda DD. DOvidio R.
Source Cereal Chemistry. 76(4):548-551, 1999 Jul-Aug.

Abstract: The complete amino acid sequence of an alpha-type gliadin from spelt wheat (spelt) has been deduced from the cloned DNA sequence and compared with alpha-type gliadin sequences from bread wheat. The comparison showed only minor differences in amino acid sequences between the alpha-type gliadin from bread wheat and the

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alpha-type gliadin from spelt. The two sequences had an identity of 98.5%. Larger differences can be found between different alpha-type gliadin amino acid sequences from common bread wheat. Because all the different classes of gliadins, alpha, beta, gamma, and omega, appear to be active in celiac disease, it is reasonably certain that the spelta gliadin is also toxic. We conclude that spelta is not a safe grain for people with celiac disease, contrary to the implications in labeling a bread made from spelt as an alternative to wheat. Our conclusions are in accord with spelt and bread wheat being classed taxonomically as subspecies of the same genus and species, Triticum aestivum L. [References: 36]

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You would think that there is enough people out there, people with celiac disease, that we'd be able to push for a better standard than 20ppm. The problem is the FDA. Too much lobbying involved. It's no different than the fight people are having with Monsanto. I hear that there are several medications that are showing promise in Canada who I think also has a better standard than us.(not positive about that though)

Make sure that you ask the doctor how long she has to stop the supplements before you have her levels tested and be sure to take them all with you when you have the appointment so the doctor knows what she is taking.

Talk to your doctor. With your family history and symptoms he/she may be able to diagnose based on resolution of your symptoms and family history. Also check with your local hospital if it has it's own lab. Mine covered any labs at a greatly reduced cost based on a sliding fee scale. Did you have an MRI before they did the spinal? Celiacs with neuro impact will have white spots on an MRI that resemble the lesions found with MS. Many neuro doctors don't know this. I went through what you did and they did a spinal on me also based on the MRI results. If my doctor had know what the UBOs (unidentified bright objects) were I would have been diagnosed a couple years sooner than I was. Make sure if you supplement that you ask your doctor which ones you need to stop taking and for how long before they do a blood test to check levels. Sublingual B12 is a good idea when we have nervous system issues, but needs to be stopped for at least a week for an accurate blood level on testing. I hope you get some answers and feel better soon.

Thanks for that. Will get her tested for deficiencies. I did take her to a naturopath and get her on a bunch of vitamins, but she never was tested via bloods, so will get on to that, thanks

Hi Could a mod please move this post: and my reply below to a new thread when they get a chance? Thanks! Matt