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Rapid Gluten Detection Test for Food Products Promises Better Product Labeling, Easier Gluten-Free Shopping

Celiac.com 11/19/2008 - In a development that could benefit people with celiac disease and gluten intolerance, a team of researchers based in Spain and the U.K. has developed a faster, easier way to test food products for the protein that triggers the adverse reactions associated with celiac disease.

Such a rapid gluten detection test for food products could help millions of people avoid the indigestion, diarrhea, bloating, and other symptoms that arise when they accidentally consume foods that contain gluten.

The research team was made up of Alex Fragoso, Ciara O'Sullivan and other colleagues, and their results will appear in the December 15 issue of the journal Analytical Chemistry.

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Their development centers on the creation of a new sensor that detects antibodies to the protein gliadin, a component of the gluten found in wheat, rye, and barley. Laboratory tests showed that the new sensor is both highly accurate and far faster than the enzyme-linked immunosorbent assay (ELISA), which is the current standard test for gliadin. The new test can detect gliadin in amounts as small as the parts per billion range, while an ELISA test requires a full 8 hours to do the same thing.

Avoiding gluten enables people with celiac disease to avoid symptoms commonly associated with celiac disease and gluten intolerance. However, since gluten can hide in so many seemingly safe foods, such as soy sauce, canned soups, and licorice candy, it can be difficult to know for certain whether foods are in fact free of gluten free. A number of prepared foods clearly list gluten ingredients on their labels, but spotting its presence can be challenging at best, and is often outright hit or miss.

A rapid, highly accurate test that can reliably spot gluten in food products promises to make it easier for manufacturers to label their products, and for people with celiac disease and gluten intolerance to avoid gluten and thereby enjoy better health.

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3 Responses:

 
Julian Ramirez
Rating: ratingfullratingfullratingfullratingfullratingfull Unrated
said this on
01 Dec 2008 7:37:56 PM PDT
Very, very good article.

 
Jeff
Rating: ratingfullratingfullratingfullratingfullratingempty Unrated
said this on
15 Dec 2008 2:45:47 AM PDT
Sounds like a very promising development, but I am a bit skeptical about exactly how the results will be used. It sounds to me like items passing the test are fine for typical Celiacs, but what about those who have other gluten problems? And what about the presence of things like oats to which some are very sensitive?

 
Ian
Rating: ratingfullratingfullratingemptyratingemptyratingempty Unrated
said this on
16 Jan 2010 8:10:23 AM PDT
Somewhat out dated article. The Elisa test claims a 10 minute
turnover time now. Florida based. down to as low as 5 ppm.
Time for an update eh!




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you're lucky you dont catch colds. im the opposite i catch everything very easily and get alot sicker than whoever i caught it from and take much longer to get better.

Even one positive can be diagnostic. This is one: Gliadin deamidated peptide IgG 33.9. If unsure, a biopsy of the small intestine will provide definite confirmation. There is a control test to validate the other ones, but I don't see it there. What is does is validate the others by checking on the overall antibody levels. But it is to detect possible false negatives. A positive is a positive. I think your daughter has joined our club.

My daughter, almost 7 years old, recently had a lot of blood work done, her Dr is out of the office, but another Dr in the practice said everything looked normal. I'm waiting for her Dr to come back and see what she thinks. I'm concerned because there is one abnormal result and I can't find info to tell me if just that one test being abnormal means anything. The reason for the blood work is mainly because of her poor growth, though she does have some other symptoms. IgA 133 mg/dl Reference range 33-200 CRP <2.9 same as reference range Gliadin Deamidated Peptide IgA .4 Reference range <=14.9 Gliadin deamidated peptide IgG 33.9 Reference range <=14.9 TTG IgA .5 Reference range <=14.9 TTG IgG <.8 Reference range <=14.9

Just watch out. I just went to the expo in Schaumburg, IL, and ended up getting glutened. I realized afterward that I ate all these samples thinking they were gluten free, and they weren't. One company was advertising some sugar, and had made some cake, but then I realized.... How do I know if this contains any other ingredients that might have gluten? Did they make it with a blender or utensils that had gluten contamination? Makes me realize the only safe things would be packaged giveaways with gluten free labeling. My fault for not thinking things through. It was just too exciting thinking i could try it all and enjoy without worry.

No fasting required for a celiac blood test unless they were checking your blood glucose levels during the same blood draw.