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Celiac Disease in China: More Common Than Believed?

Celiac.com 04/23/2009 - Celiac disease is far more common among people of European descent, especially northern European descent, than among other populations. In East Asia, including China, there have been only sporadic reports of celiac disease. Historically, celiac disease has been only rarely reported in Asia.

Due to the absence of reports, and since Asian diets are traditionally low in wheat, barley or rye, it has been taken as a given that Asian populations don't really suffer from celiac disease. Still, there have been no comprehensive studies undertaken to verify this notion.

Recently, a team of Chinese researchers set out to put that assumption to the test, and to determine if celiac disease is as rare in China as presently believed.

The team was made up of L. L. Jiang, B.L. Zhang, and Y.S. Liu. of the department of Gastroenterology, the First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou 310003, China.

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The team performed capsule endoscopy on 62 patients with chronic diarrhea from June 2003 to March 2008. Four of those patients were clinically diagnosed with celiac disease. Endoscopy of these patients revealed classic signs of celiac disease: shortened villi of the proximal small bowel, and atrophy of the mucous membrane. Duodenal biopsy showed pathological changes of mucosa to be Marsh 3 stage celiac disease. All four patients saw significant abatement of symptoms and an improvement in their conditions when placed on gluten-free diets.

Recognizing the small sample size, the researchers hypothesize that celiac disease might be far more common in than believed in China, especially in those northern areas where wheat is the main food.

The research team points out that if celiac disease is indeed more common than thought, its diagnosis might be routinely missed, as its symptoms might be be easily covered by the symptoms from other clinical conditions, especially those subclinical patients who lack obvious symptom or those patients with extraintestinal symptoms as the first expression of the disease.

 J Zhejiang Univ Sci B. 2009 Mar;10(3):168-71.

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1 Response:

 
Lol
Rating: ratingfullratingfullratingfullratingfullratingempty Unrated
said this on
16 Aug 2013 4:55:13 PM PDT
This is known as the lazy disease in Asia. If you have this disease, you will starve because the government has no welfare benefit for these people.




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you're lucky you dont catch colds. im the opposite i catch everything very easily and get alot sicker than whoever i caught it from and take much longer to get better.

Even one positive can be diagnostic. This is one: Gliadin deamidated peptide IgG 33.9. If unsure, a biopsy of the small intestine will provide definite confirmation. There is a control test to validate the other ones, but I don't see it there. What is does is validate the others by checking on the overall antibody levels. But it is to detect possible false negatives. A positive is a positive. I think your daughter has joined our club.

My daughter, almost 7 years old, recently had a lot of blood work done, her Dr is out of the office, but another Dr in the practice said everything looked normal. I'm waiting for her Dr to come back and see what she thinks. I'm concerned because there is one abnormal result and I can't find info to tell me if just that one test being abnormal means anything. The reason for the blood work is mainly because of her poor growth, though she does have some other symptoms. IgA 133 mg/dl Reference range 33-200 CRP <2.9 same as reference range Gliadin Deamidated Peptide IgA .4 Reference range <=14.9 Gliadin deamidated peptide IgG 33.9 Reference range <=14.9 TTG IgA .5 Reference range <=14.9 TTG IgG <.8 Reference range <=14.9

Just watch out. I just went to the expo in Schaumburg, IL, and ended up getting glutened. I realized afterward that I ate all these samples thinking they were gluten free, and they weren't. One company was advertising some sugar, and had made some cake, but then I realized.... How do I know if this contains any other ingredients that might have gluten? Did they make it with a blender or utensils that had gluten contamination? Makes me realize the only safe things would be packaged giveaways with gluten free labeling. My fault for not thinking things through. It was just too exciting thinking i could try it all and enjoy without worry.

No fasting required for a celiac blood test unless they were checking your blood glucose levels during the same blood draw.