No popular authors found.


Get Celiac.com's E-Newsletter

Categories

No categories found.







Ads by Google:


Questions? Join Our Forum:
~1 Million Posts
& Over 66,000 Members!



SHARE THIS PAGE:
Celiac.com Sponsors:

Long-term Clinical Significance of Thyroid Autoimmunity in Children with Celiac Disease

Celiac.com 03/03/2010 - A team of researchers set out to assess long-term outcomes of thyroid function and autoimmunity in a large population of children with celiac disease.

The research team included Alessandra Cassio, MD, Giampaolo Ricci, MD, Federico Baronio, MD, Angela Miniaci, MD, Milva Bal, MD, Barbara Bigucci, MD, Veronica Conti, MD, and Alessandro Cicognani, MD.

To accomplish this, they conducted a longitudinal, retrospective study at the Pediatric Department, University of Bologna, Italy (duration of follow-up, 8.9 +- 4.0 years).

Ads by Google:

In all, the team examined one hundred thirty-five consecutive patients diagnosed between June 1990 and December 2004 and followed on a gluten-free diet.

To be included, researchers required study subjects to maintain good dietary compliance and duration of follow-up for at least 3 years. A total of 101 patients showed no positive antithyroid titers during the follow-up, while 86 remained euthyroid; 15 showed high thyroid-stimulating hormone values at diagnosis that normalized in 11 cases after 12 to 18 months of gluten withdrawal. A total of 31 patients showed persistently positive antibody titers, with 23 of those (74%) remained consistently euthyroid during the follow-up and 8 (26%) had a subclinical hypothyroidism.

Children with growth retardation or gastroenterological symptoms at diagnosis and different lengths of gluten exposure showed similar rates of positive antibodies.

In children with celiac disease, antithyroid antibodies have a low clinical value for predicting the development of thyroid hypo-function during the indicated surveillance period. They encourage a more comprehensive follow-up.

Source:
J Pediatr. Volume 156, Issue 2, Page A2; February 2010

Celiac.com welcomes your comments below (registration is NOT required).












Related Articles



Comments




Rate this article and leave a comment:
Rating: * Poor Excellent
Your Name *: Email (private) *:




In Celiac.com's Forum Now:


I'm hoping to donate to celiac research this year. Does anyone have recommendations as to where to donate? Celiac Disease Foundation? Celiac research at a hospital or university? Thanks!

Thank you so much for your responses!! It is so hard because there are so many unknowns, inconclusive results, and lots of waiting!! I didn't realize it was so difficult to even get the tests to begin with. Thank you both SO much. I feel much better & am more comfortable going into my doctors app...

Just looking at its name, one might wonder if buckwheat is safe for people on a gluten-free diet. However, unlike its name, buckwheat does not naturally contain any wheat or gluten. As a result, buckwheat is generally safe for people with celiac disease on a gluten-free diet. Turns out that buc...

Oh my I just re read your post. Ok now I am going to definitely say yes-you need to find someone who will test you. If this Dr. will not you may want to look for one who will. I slowly reveal my issues on here and I still keep things close to the vest. My pregnancies/labor/deliveries we...

I try not to take a lot of ibuprofen as I know it's not great for my gut. But, when I need it, I take Costco's Kirkland ibuprofen. It is labelled gluten free and I have had no issues with it.