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Celiac and Thyroid Antibodies are High in Type 1 Diabetics


Diabetes Care celiac antibody research

Celiac.com 08/02/2010 - It has been well documented that Type 1 diabetics' risk for thyroid disease and celiac disease are very high. As such the American Diabetics Association advises young children and adolescents that are diagnosed with Type 1 diabetes, to also have their thyroid function monitored and undergo celiac screening.

Between 1990 and 2008, under the direction of Dr. Katharina Warncke of Technische Universitat Munchen, data from 28, 671 type 1 diabetes patients under the age of 30 with at least one autoantibody measurement, were enrolled  in a study in Germany and Austria to assess the risks of additional autoimmunities for type 1 diabetics.

Of the 15,000 patients that were screened for beta-cell antibodies, 81.6% of them were discovered to have at least one. Those that did not have any beta-cell antibodies were found to be considerably younger than the patients with the antibodies when they first developed diabetes. However, patients with beta-cell antibodies were not more or less likely to have additional markers, indicating that autoimmunity cannot be established as an indicator of additional autoimmunities.

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Of the 25,000 patients that were screened for thyroid autoantibodies, 19.6% had positive results. And of the 14, 300 who were screened for tissue transglutaminase, 10.7% tested positive for the celiac disease marker.

Female patients were more likely to be thyroid antibody-positive, and patients with thyroid antibodies were usually older and had a longer period of diabetes when compared to patients without the antibodies. Patients with positive tissue transglutaminase assays where discovered to have a longer duration of diabetes as well.

Of the patients studied for parietal cell antibodies, only 283 were found to be positive. Those patients were also older and had a longer duration of diabetes than those found to be negative. Ninety-Four patients were shown to have anti-adrenal antibodies.

Unfortunately, the researchers for the study did not have data on the actual reasons for parietal cell antibody and anti-adrenal antibody testing. So the high numbers of patients with positive results cannot be evaluated accurately. However the researchers indicate that it may be due to selection factors such as underlying disorders or cost factors.

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1 Response:

 
natasha baissero
Rating: ratingfullratingfullratingfullratingfullratingempty Unrated
said this on
09 Aug 2010 7:52:35 PM PDT
My husband is type 1 diabetic for 29 years. Great information




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If you're going to continue to push for a diagnosis stay on gluten! A break could lead to a false negative. It's a lot harder to go off it and then go back on...

I still prefer steaming, but I wash my white rice throughly. I purchase California rice which has a lower level of arsenic. Moderation is key to most everything! ?

I eat pretty much grain free just fine, I eat fats instead. But on a side note I posted some specialty and grain free options as of late in the food alternative page where I list companies and food product alternatives. I honestly just welcomed bread back into my life, I found a company that makes grain free bread out of nut flours. Given you have to toast the dang bread to use it well but seems to work decently. Pasta there are carb free versions out there, and there are ones made with quinoa, buckwheat, or other grains, I even know one company that makes nut flour based ones. You can get these gluten-free options and avoid the rice. As to levels of arsenic they do test foods for these, and all should be safe, the trace amounts and the sheer amount you would have to eat to get effected is staggering, a bit of rice will not hurt you regardless if your concerned I know gluten-free watchdog does arsenic testing on products you could check and find the "safest ones" for your concerns.

I've forgotten them, just remember the good stuff. Weekends in Baja or Vegas or up Pacific highway to see the Redwoods and Frisco. Watching the sunrise at Mount Soledad and watching it drop into the Pacific in the evening. Carne Asada Burritos on Garnet* Solana beach ale* Gorgeous women entranced by my exotic accent, humboldt county weed, raves at the romper room, *1.99 are you out of your mind Denny Breakfasts, Christmas on the beach, *Beers in the gaslamp quarter. I need one of these * which by the power of my imagination have magically become gluten free AANNNYWAAY... Arsenic in rice. Yeah.

Oh, it definitely struck me as very odd! It also says "no significant increase in intraepithelial lymphocytes". That's their favorite word I guess! My blood work pre-biopsy also showed increase lymphocytes and my primary doctor said it usually means increased inflammation. Doing all the things I can now---filing a complaint, I've emailed my doctors to tell them I'm upset and don't think I received proper care, I'm in the process of trying to see a naturopath that diagnosed a friend of a friend w celiac. I'm going to see if i can get the other blood work done with them---and I've been gluten free for a week and a half!