No popular authors found.
Ads by Google:

Categories

No categories found.


Get Celiac.com's E-Newsletter





Ads by Google:


Follow / Share


  FOLLOW US:
Twitter Facebook Google Plus Pinterest RSS Podcast Email  Get Email Alerts
SHARE:

Popular Articles

No popular articles found.
Celiac.com Sponsors:

Better Celiac Diagnosis Has No Impact On Death Rates


New AJG study on celiac diagnosis and death rates.

Celiac.com 03/02/2011 - New blood screening tests have improved rates of diagnosis for celiac disease in recent decades, but better diagnosis has not reduced celiac-associated deaths, according to a report by UK researchers in the American Journal of Gastroenterology.

After serologic tests became available, there was an approximate tenfold increase in the numbers of people being diagnosed with celiac disease. Intuitively, one would expect this increase in diagnosis to be followed by a decrease in celiac-related deaths. The idea being that earlier diagnosis means earlier treatment with gluten-free diet, and, ideally, less associated conditions and deaths.

However, the newest study in this area shows evidence of any change in all-cause mortality among people with celiac disease. That means that even with better, earlier diagnosis, people with celiac disease are still dying at the same rates as before.

Researcher Dr. Matthew J. Grainge, of the University of Nottingham, told Reuters Health that his team "found that people with celiac disease have a 37% increase in all-cause mortality compared with the general population."

His team found that people diagnosed with celiac disease since 2000 have a similar mortality risk as those diagnosed earlier despite the introduction of serological tests, "which has probably resulted in milder cases being identified," Grainge said.

Ads by Google:

For their study, the research team reviewed data on 1092 celiac disease patients diagnosed from the late 1950s onward, and who had been followed for a minimum of two years.

The team examined outcomes from 1978 until death or through the end of 2006. All study subjects were diagnosed at a single center and the study covered both the pre- and post-serology era. The study covered more than 10,000 person years of follow-up,  and tallied a total of 142 deaths.

The study revealed a significantly increased all-cause standardized mortality ratio (SMR) of 1.37. This was higher for men (SMR, 1.86) than for women (SMR, 1.10). Study subjects had higher rates of death from cancer (SMR, 1.61) digestive (SMR, 2.19) and respiratory diseases (SMR, 1.57) compared to the general population. In all, there were 21 deaths from respiratory diseases, 11 of those from pneumonia.

According to the research team, this data supports current guidelines recommending pneumococcal vaccination for people with celiac disease.

In conclusion, the researchers note that the results may offer doctors "an opportunity to reduce mortality following pneumococcal infection by increasing the uptake of vaccination against this pathogen as vaccination rates are currently well below 50%."

Source:

Celiac.com welcomes your comments below (registration is NOT required).












Related Articles



3 Responses:

 
Amy Buchert
Rating: ratingfullratingfullratingfullratingfullratingfull Unrated
said this on
07 Mar 2011 11:45:08 AM PDT
Great information for celiacs!! I suffer from upper respiratory infections almost yearly and will now receive the Pneumococcal vaccine next fall.

 
Dr. Murdocco
Rating: ratingfullratingfullratingfullratingfullratingempty Unrated
said this on
07 Mar 2011 5:09:38 PM PDT
Interesting and informative.

 
Helen Haas
Rating: ratingfullratingfullratingfullratingfullratingempty Unrated
said this on
08 Mar 2011 3:47:22 PM PDT
I find this article very helpful I have had celiac since 78 years old now 83 and doing just fine the GF breads have gotten so much better since I first was diagnosis the pies & cakes haven't improved much.




Rate this article and leave a comment:
Rating: * Poor Excellent
Your Name *: Email (private) *:




In Celiac.com's Forum Now:


This article, and the comments below, may be helpful: https://www.celiac.com/articles/21721/1/How-Celiacs-can-Deal-with-Accidental-Gluten-Ingestion/Page1.html

Long ignored and dismissed as unscientific and crude, are intestinal worms destined to be the future of autoimmune disease treatments? Hookworms. Intestinal parasites. They sound gross. The thought of having one's gut infected with a parasitic worm generally makes people's skin crawl. Indeed, in...

well, we're in sort of similar positions but can l ask what made you go gluten-free 3 years ago? You've kept the diet for quite some time so where the health problems serious? at the time was seeking testing not an option? For myself, l absolutely tried everything to gain weight ...

I can not add anything else, but I hope you feel better fast!

Welcome! I am so sorry that you are dealing with this. With all your testing was active celiac disease ruled out? Did they check for UC or Crohn's? Flies? I am on the West Coast. The wind is usually too steady for any insect to hang around at the beach, but I recall getting attacked by...