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Shorter Overall Fertility Span for Women with Untreated Celiac Disease


New research on fertility span in women with untreated celiac disease.

Celiac.com 06/20/2011 - A team of researchers set out to assess menopause-associated disorders and fertile life span in women with untreated celiac disease compared to those who followed a long-term gluten-free diet.

The research team included Antonella Santonicola, MD, Paola Iovino, MD, Carmelina Cappello, MD, Pietro Capone, MD, Paolo Andreozzi, MD, and Carolina Ciacci, MD.

For their study, the team recruited 33 post-menopausal women with untreated celiac disease, 25 celiac women who had followed a gluten-free diet for at least ten years before menopause, and 45 healthy volunteers as a control group.

The team used the Menopause Rating Scale questionnaire to gather information on menopause-associated disorders among study participants. They also used the International Physical Activity Questionnaire to chart information on physical activity.

Overall, results showed that the women with untreated celiac disease had a shorter overall fertile life spans than did the control women. This was due to both a higher age of menarche and a lower age of menopause (P G 0.01).

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Women with untreated celiac disease also showed higher scores for hot flushes, muscle/joint problems, and irritability than the control group. An increase of 49.4%, 121.4%, and 58.6%, respectively; P G 0.05).

In contrast with the untreated celiac women, those who followed a long-term gluten-free diet showed no significant difference in the duration of fertile life span. They also had about half as many muscle/joint problems than the untreated group, with a total reduction of 47.1%; P G 0.05.

The data show that women with untreated celiac disease have later menarche and earlier menopause, which shortens their fertility periods compared to healthy women without celiac disease. Also, they perceive hot flushes and irritability much more intensely than control subjects.

Women with celiac disease can prolong their fertility life span at least ten years prior to starting menopause.

Lastly, untreated celiac disease may increase women's overall discomfort levels, and thus contribute to low physical exercise and/or poorer quality of life frequently reported by untreated celiac women.

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1 Response:

 
CeliBelli
Rating: ratingfullratingfullratingemptyratingemptyratingempty Unrated
said this on
27 Jun 2011 10:39:21 PM PST
This write up about the article doesn't address a number of questions crucial to women, such as how much higher on average was the onset of menarche, and how much lower was the onset of menopause? Significantly delayed menarche has a number of ramifications for a young woman's physical development and mental well being. Early menopause can be a devastating surprise for women who postpose childbearing, and has significant health ramifications resulting from loss of hormone production, including accelerated loss of bone density, accelerated aging, and premature changes in sexual health and functioning. All of these impact a woman's health well beyond the issue of fertility. If the study did not broach these ramifications of their findings, it should have. Focusing such a study only on discomfort and physical activity is short-sighted, and barely scratches the surface.




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