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Slightly Higher Risk of Urinary Stones in Patients With Biopsy-verified Celiac Disease

Celiac.com 04/27/2012 - Urinary stone disease is condition often caused by malabsorption. Because of its high prevalence and incidence, doctors regard it as a serious issue. However, there are few population-based studies on the risk of urinary stone disease in patients with celiac disease.

Photo:CC--rkramer62A team of medical researchers recently studied the risk of urinary stone disease in people with celiac disease. The research team included J. F. Ludvigsson, F. Zingone, M. Fored, C. Ciacci and M. Cirillo.

For their population-based cohort study, the team used small intestinal biopsy reports gathered from all 28 Swedish pathology departments from 1969 to 2008. In all, the team found 28,735 patients with celiac disease, all with the equivalent of Marsh 3 villous atrophy.

They then isolated a control group of 142,177 people from the Swedish general population. They matched patients and control subjects for age, gender, age, county and calendar year.

Using Cox regression, they estimated hazard ratios for future urinary stone disease. Using conditional logistic regression they then calculated odds ratios for urinary stone disease before celiac disease diagnosis.

The team used Swedish National Patient Register data on inpatient care, outpatient care and day surgery to find cases of urinary stone disease.

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During follow-up, a total of 314 people with celiac disease developed urinary stone disease, compared with 1142 from the control group.

These numbers indicated that people with celiac disease face a 27% increased risk of urinary stone disease [95% confidence interval (CI) = 1.12–1.44].

For celiac disease, patients the absolute risk of developing urinary stone disease was 107 cases per 100,000 person-years; which corresponds to an excess risk of 23 cases per 100,000 person years.

Men and women faced similar risk levels, and showed no difference with respect to age at celiac disease diagnosis.

Using conditional logistic regression the team found that celiac disease patients also faced a moderately higher risk of prior urinary stone disease (OR = 1.19; 95% CI = 1.06–1.33).

The study indicates that people with celiac disease face a slightly higher risk of urinary stone disease both before and after celiac disease diagnosis.

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1 Response:

 
jairo naranjo
Rating: ratingfullratingfullratingfullratingfullratingfull Unrated
said this on
08 May 2012 2:27:00 PM PDT
Excelente comentario.




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these sound like celiac reactions yes ... basically avoid anything that causes the reaction always and find your self a great natural practitioner and rebuild your body .. Rest vitamins digestive enzymes and very strict diet Good Luck

Hey guys im from the UK and this site is really helpful for me. I've been diagnosed with Coeliac disease (uk spelling) for 5 years now and I slowly became dairy intolerant, which makes sense and I live with this now... but now alcohol has turned on me. I don't drink often and I don't drink a lot (I used to in my uni years) but the reaction the next day (or same night) is horrific. I wondered if anyone else had this problem. I start with sweats and dizziness , then the stomach cramps cause chronic diarrhoea ... I then start to vomit until my body is empty .... this isn't the bad part. After my body is empty I go into a fit like state and cannot move walk talk or anything... the cold sweats start but I'm burning up. The stomach spasms are awful, I have to lie in bed flat with cold wet towels on my head and belly. I cannot speak or move for hours and feel so weak and unstable ..: this lasts all day and I can't eat or drink anything but I don't feel myself for three or four days. I avoid drinking but sometimes it's nice to go out and have some... am I alcohol intolerant??!! Does anyone else have this!? I obviously stick to gluten free drinks and have a very strict diet! Im a severe case! Thankyoy steph

I'm going to contact my primary Dr and see what his take is on this. I know I can't wait another 4 weeks to go to my gastroenterologist. Today marks day 23 of diarrhea. Since switching back to Imodium it has gotten worse. I think that the other 2 medications, even though I couldn't tolerate them and they didn't stop the diarrhea, at least slowed it down a little. If my primary has no clue, then I am definitely contacting U of C. The only thing stopping me is that they are out of network for my insurance plan so it would be more costly.

Spring is cherry blossom season, which means that actual cherries are still far enough off that we'll have to leave their deliciousness ahead, and turn to their canned cousins for this recipe. Turns out, that's not a bad thing. Canned cherries make a tasty cornerstone to this super quick, super-easy no-bake cheesecake. Topped with lovely cherries, this no-bake cheesecake is a contender. Enjoy! View the full article

Haha todays cheat day and I cant decide if i want pizza or mac and cheese lmao oh the struggle.