Celiac Disease and Gluten-Free Diet Support
- Questions? Join our forum: Nearly 1 MILLION POSTS, and over 62,000 MEMBERS!
Follow / Share
|Get Email Alerts|
- Safe Gluten-Free Food List (Safe Ingredients)
- Unsafe Gluten-Free Food List (Unsafe Ingredients)
- Gluten-Free Alcoholic Beverages
- Celiac Disease Symptoms
- The Gluten-Free Diet 101 - A Beginner's Guide to Going Gluten-Free
- Interpretation of Celiac Disease Blood Test Results
- Is Buckwheat Flour Really Gluten-Free?
Can Head Trauma Trigger Celiac Disease?
Celiac.com 09/12/2013 - There is evidence that certain types of gut trauma can trigger celiac disease, but almost nothing is know about whether traumatic brain injury might trigger a neurological form of celiac disease in some individuals.
TG6 is a brain expressed form of transglutaminase that seems to be connected to neurological expressions of celiac disease.
Researchers Jonas F Ludvigsson and Marios Hadjivassiliou wanted to test the hypothesis that earlier brain injury due to head trauma may be more common in patients with celiac disease, potentially through trauma-induced TG6 leading to interaction with TG2.
Ludvigsson and Hadjivassiliou are variously affiliated with the Department of Pediatrics at Örebro University Hospital in Örebro, Sweden, the Clinical Epidemiology Unit, Department of Medicine at Karolinska Institutet in Stockholm, Sweden, the Division of Gastroenterology and Hepatology at the Mayo Clinic College of Medicine in Rochester, USA, and with the Department of Neurology at Royal Hallamshire Hospital in Sheffield, UK.
They then assessed the risk of earlier head trauma in celiac disease patients compared to the risk in 144,522 controls matched for age, sex, county and calendar year. They used logistic regression to calculate odds ratios (ORs).
They found that a record of earlier head trauma in 981 (3.4%) patients with celiac disease, and in 4,449 (3.1%) control subjects.
People who had suffered from head trauma showed a 1.10-fold increased risk of future celiac disease (95% CI = 1.02-1.17); independent of sex or age at celiac disease.
The highest risk of future celiac disease was seen during the first year after trauma. There was no connection between severity of trauma and risk of developing celiac disease.
These results show a very small excess risk for future celiac disease in individuals with an earlier head trauma.
Celiac.com welcomes your comments below (registration is NOT required).
Are Advil and Aspirin Promoting Celiac Disease?
Each year, non-steroidal anti-inflammatory drugs (NSAIDs), such as ibuprofen, acetaminophen, and aspirin, send more than 100,000 people to the hospital, and cause over 16,000 deaths.... [READ MORE]
Hepatitis B Vaccine and Boosters Less Effective in People With Celiac Disease
A team of researchers recently took a look at how well the hepatitis B vaccine protected people with celiac disease over time.... [READ MORE]
Rod-shaped Bacteria in Proximal Small Intestine Tied to Celiac Disease in Children
Research indicates that rod-shaped bacteria, of the species Clostridium, Prevotella, and Actinomyces, in the proximal small intestine may contribute to some cases of celiac disease in children.... [READ MORE]
Helicobacter Pylori Infection in Celiac Disease Patients
In is known that increased
duodenal intraepithelial lymphocytes (IEL) are more common in celiac patients
with Helicobacter pylori gastritis (H.... [READ MORE]
Jefferson Adams is a freelance writer living in San Francisco. His poems, essays and photographs have appeared in Antioch Review, Blue Mesa Review, CALIBAN, Hayden's Ferry Review, Huffington Post, the Mississippi Review, and Slate among others.
He is a member of both the National Writers Union, the International Federation of Journalists, and covers San Francisco Health News for Examiner.com.View all articles by Jefferson Adams
In Celiac.com's Forum Now:
Celiac.com Celiac Disease & Gluten-Free Diet Forum - All Activity