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  • Jefferson Adams
    Jefferson Adams

    Stress Common Before Celiac Diagnosis

    Reviewed and edited by a celiac disease expert.
    Stress Common Before Celiac Diagnosis - Photo: CC--Bottled Void
    Caption: Photo: CC--Bottled Void

    Celiac.com 01/13/2014 - Researchers have documented stress in patients with various immune-mediated diseases but little is known about stressful life events and the onset of celiac disease from a patient's perspective. 

    Using the standardized interview of Paykel, a team of researchers set out to examine the relationship of stressful events in patients diagnosed with celiac disease, and to compare them with a control group of gastroesophageal reflux patients.

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    The research team included C. Ciacci, M. Siniscalchi, C. Bucci, F. Zingone, I. Morra, and P. Iovino, of the Department of Medicine and Surgery at the University of Salerno in Italy.

    They found that 186 adults (67.2%) with celiac disease reported more frequent and more severe life events in the years prior to the diagnosis, compared with 96 control patients (37.5%, p < 0.001, mean Paykel score 11.5 vs. 13.4, p = 0.001, respectively).

    Overall, the time lapse between the event and the diagnosis was about the same for celiac patients (5.5 months) as it was for control patients for (5.7 months).

    A total of 20.3% of celiac women considered pregnancy a negative event , but no control women defined pregnancy as a negative event..

    Repeat analyses subgroup of patients of both groups with diagnosis made within one year of onset of symptoms confirmed these findings.

    Data indicate that, before diagnosis, people with celiac disease faced stressful events that were more frequent, but less severe than in the control group suggesting that life events may impact the clinical appearance of celiac disease or accelerate its diagnosis.

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  • About Me

    Jefferson Adams

    Jefferson Adams is Celiac.com's senior writer and Digital Content Director. He earned his B.A. and M.F.A. at Arizona State University. His articles, essays, poems, stories and book reviews have appeared in numerous magazines, journals, and websites, including North American Project, Antioch Review, Caliban, Mississippi Review, Slate, and more. He is the author of more than 2,500 articles on celiac disease. His university coursework includes studies in science, scientific methodology, biology, anatomy, physiology, medicine, logic, and advanced research. He previously devised health and medical content for Colgate, Dove, Pfizer, Sharecare, Walgreens, and more. Jefferson has spoken about celiac disease to the media, including an appearance on the KQED radio show Forum, and is the editor of numerous books, including "Cereal Killers" by Scott Adams and Ron Hoggan, Ed.D.

    >VIEW ALL ARTICLES BY JEFFERSON ADAMS

     


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