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Should Celiac Disease Screening Focus on Kids With IBS?

Celiac.com 06/23/2014 - Previous studies of adults have shown a strong connection between celiac disease and irritable bowel syndrome, but there has been very little data for children.

Photo: Wikimedia Commons--Ernst VikneA research team recently set out to determine rates of celiac disease in children with ongoing abdominal pain.

The researchers included Fernanda Cristofori, MD; Claudia Fontana, MD; Annamaria Magistà, MD; Teresa Capriati, MD; Flavia Indrio, MD; Stefania Castellaneta, MD; Luciano Cavallo, MD; Ruggiero Francavilla, MD, PhD.

They are variously affiliated with the Interdisciplinary Department of Medicine, Pediatric Section at the University of Bari ’s Giovanni XXIII Hospital in Bari, Italy, the Department of Pediatrics at Ravenna Hospital in Ravenna, Italy, and the Department of Pediatrics at San Paolo Hospital in Bari, Italy.

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For their prospective observational study, the team tested 782 children who presented with abdominal pain-related disorders, 270 with IBS, 201 with functional dyspepsia, and 311 with functional abdominal pain. All subjects were treated between 2006 and 2012 at the university hospital of Bari, the regional tertiary referral center for gastrointestinal disorders.

As a primary screen for celiac disease, the researchers used serum tests for immunoglobulin A, immunoglobulin A antitissue transglutaminase, and endomysial antibodies. They then confirmed the diagnosis with upper endoscopy, including multiple duodenal biopsies.

Overall, fifteen patients tested positive for celiac. They included
12 children with IBS (4.4%; 95% confidence interval [CI], 2.5% - 7.6%), 2 children with functional dyspepsia (1.0%; 95% CI, 0.2% - 3.5%), and 1 child with functional abdominal pain (0.3%; 95% CI, 0.1% - 1.7%).

The team concluded that treating IBS as a high-risk condition for celiac disease might be help pediatric primary care specialists extend celiac disease screening to children with IBS
rather than testing all children with recurrent abdominal pain,

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1 Response:

 
Rena

said this on
01 Jul 2014 4:44:59 AM PST
I think any child should be tested for gluten intolerance (with a DNA test from a blood sample) and if it shows one marker or more, go gluten free. Kids that have a problem thriving, are sick a lot or are lactose intolerant may be more at risk.




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Yep. Initially I had the full panel. DGP was the only positive and it's the only one my doctor orders now.

Well I wish mine was dia. earlier, I got all kinds of other food issues, and other auto immune disease that came up as complications. If you deal with and change over now you can prevent a even more limited diet. I was running a bucket list thinking I was going to die before my dia. I had slight ...

So, do they just test your DGP like they just test my TTG?

The only test I have had done is the TTG because that's what I had done initially after taking matters into my own hands and going to my local health fair. Celiac is so common they do that screening at our health fair. My number was so high that my doctor didn't order other labs and went straight...

Celiac used to be considered a children's disease - so, by the old standards, you are a bit old to be diagnosed. We now know that Celiac can start at any age. I don't know if you are a male or a female, but untreated Celiac can lead to miscarriages and infertility. And all the other stuff...