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Should Celiac Disease Screening Focus on Kids With IBS?
Celiac.com 06/23/2014 - Previous studies of adults have shown a strong connection between celiac disease and irritable bowel syndrome, but there has been very little data for children.
A research team recently set out to determine rates of celiac disease in children with ongoing abdominal pain.
The researchers included Fernanda Cristofori, MD; Claudia Fontana, MD; Annamaria Magistà, MD; Teresa Capriati, MD; Flavia Indrio, MD; Stefania Castellaneta, MD; Luciano Cavallo, MD; Ruggiero Francavilla, MD, PhD.
They are variously affiliated with the Interdisciplinary Department of Medicine, Pediatric Section at the University of Bari ’s Giovanni XXIII Hospital in Bari, Italy, the Department of Pediatrics at Ravenna Hospital in Ravenna, Italy, and the Department of Pediatrics at San Paolo Hospital in Bari, Italy.
For their prospective observational study, the team tested 782 children who presented with abdominal pain-related disorders, 270 with IBS, 201 with functional dyspepsia, and 311 with functional abdominal pain. All subjects were treated between 2006 and 2012 at the university hospital of Bari, the regional tertiary referral center for gastrointestinal disorders.
As a primary screen for celiac disease, the researchers used serum tests for immunoglobulin A, immunoglobulin A antitissue transglutaminase, and endomysial antibodies. They then confirmed the diagnosis with upper endoscopy, including multiple duodenal biopsies.
Overall, fifteen patients tested positive for celiac. They included
12 children with IBS (4.4%; 95% confidence interval [CI], 2.5% - 7.6%), 2 children with functional dyspepsia (1.0%; 95% CI, 0.2% - 3.5%), and 1 child with functional abdominal pain (0.3%; 95% CI, 0.1% - 1.7%).
The team concluded that treating IBS as a high-risk condition for celiac disease might be help pediatric primary care specialists extend celiac disease screening to children with IBS
rather than testing all children with recurrent abdominal pain,
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Gender and Mental Health are Factors in Irritable Bowel Disease-related Symptoms in Celiac Disease
In the majority of people with celiac disease,
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No Link Found Between Celiac Disease and Irritable Bowel Syndrome
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The Canadian Medical Association Journal (Hoey, 2002;166:479-80) published
the following, Irritable Bowel Syndrome: Could it be Celiac Disease?,
as excerpted below.... [READ MORE]
At Least 4.6% of People Diagnosed With Irritable Bowel Syndrome Have Undetected Celiac Disease
Lancet Nov 2001
Volume 358, Number 9292 1504-08 03
Celiac.... [READ MORE]
Jefferson Adams is a freelance writer living in San Francisco. His poems, essays and photographs have appeared in Antioch Review, Blue Mesa Review, CALIBAN, Hayden's Ferry Review, Huffington Post, the Mississippi Review, and Slate among others.
He is a member of both the National Writers Union, the International Federation of Journalists, and covers San Francisco Health News for Examiner.com.View all articles by Jefferson Adams
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