No popular authors found.
Ads by Google:

Categories

No categories found.


Get Celiac.com's E-Newsletter




Ads by Google:



Follow / Share


  FOLLOW US:
Twitter Facebook Google Plus Pinterest RSS Podcast Email  Get Email Alerts

SHARE:

Popular Articles

No popular articles found.
Celiac.com Sponsors:

Gluten-free Diet Promotes Weight Loss, Inflammation Reduction and Prevents Insulin Resistance

Celiac.com 08/18/2014 - A team of researchers recently set out to better understand the effects of gluten-free diets on obesity.

Image of International Diabetes Symbol: Wikimedia Commons--Fred the OysterThe research team included F.L. Soares, R. Matoso de Oliveira, L.G. Teixeira, Z. Menezes, S.S. Pereira, A.C. Alves, N.V. Batista, A.M. de Faria, D.C. Cara, A.V. Ferreira, and J.I. Alvarez-Leite. They are affiliated with the Departamento de Alimentos, Faculdade de Farmácia, Instituto de Ciências Biológicas, Universidade Federal de Minas Gerais in Belo Horizonte, Brazil.

Specifically, the team wanted to determine whether a gluten-free diet can prevent the expansion of adipose tissue, and its consequences.

For their study, the team fed C57BL/6 mice a high-fat diet containing either 4.5% gluten (Control) or no gluten (GF). They noted body weight and adiposity gains, leukocyte rolling and adhesion, macrophage infiltration and cytokine production in adipose tissue.

Ads by Google:

The team measured blood lipid profiles, glycaemia, insulin resistance and adipokines. They also assessed the expression of the PPAR-α and γ, lipoprotein lipase (LPL), hormone sensitive lipase (HSL), carnitine palmitoyl acyltransferase-1 (CPT-1), insulin receptor, GLUT-4 and adipokines in epidydimal fat.

Gluten-free animals showed less body weight and adipose gain, with no changes in food intake or lipid excretion. These results were associated with up-regulation of PPAR-α, LPL, HSL and CPT-1, which are related to lipolysis and fatty acid oxidation.

The team also saw improved glucose regulation, and pro-inflammatory profile-related over-expression of PPAR-γ. Intravital microscopy revealed a lower number of adhered cells in the adipose tissue microvasculature. The over-expression of PPAR-γ is related to the increase of adiponectin and GLUT-4.

The results of this study suggest that gluten-free diets can be helpful in reducing fat gain, inflammation and insulin resistance. They suggest that a gluten-free diet should be tested as a way of preventing the development of obesity and metabolic disorders.

Source:

Celiac.com welcomes your comments below (registration is NOT required).





Spread The Word







Related Articles



4 Responses:

 
gina
Rating: ratingfullratingfullratingfullratingemptyratingempty Unrated
said this on
23 Aug 2014 5:39:26 AM PDT
Not enough data.

 
Roberta Steiner
Rating: ratingfullratingfullratingfullratingemptyratingempty Unrated
said this on
25 Aug 2014 11:50:04 AM PDT
I found this article most interesting since in the year before I was diagnosed with celiac disease and went GF I lost 15 pounds with out trying. When I went GF, I was able to regain 10 of those pounds and have happily kept the weight on. My bone mass also increased.

 
Mary Thorpe
Rating: ratingfullratingfullratingfullratingfullratingempty Unrated
said this on
27 Aug 2014 6:17:03 AM PDT
I was pre-diabetic before going GF. My glucose tolerance test profile became normal over the years on the diet and I always wondered if it was because I'm consuming fewer carbs on the GF diet, or if it was simply because of being GF. This study might give a clue. The article doesn't indicate whether the amount of carbs in the diets was the same. I would hope so but will have to check the article to make sure.

 
Fredburgin
Rating: ratingfullratingfullratingfullratingemptyratingempty Unrated
said this on
07 Dec 2014 11:10:16 PM PDT
This article is really interesting, as they are providing the free diet plans it will surely help the people and also to get relief from this celiac disease.




Rate this article and leave a comment:
Rating: * Poor Excellent
Your Name *: Email (private) *:




In Celiac.com's Forum Now:

All Activity
Celiac.com Celiac Disease & Gluten-Free Diet Forum - All Activity

I will just share an experience I had..... I went to a steak house where there weren't a lot of safe options for me. So, I decided just to order a drink and eat later. I asked the bar tender about how they made their margaritas - fresh lime juice, fresh orange juice and gluten free tequila. gluten-free all the way. My husband went back to order for me and noticed that the bartender was juicing the limes and serving bread to the customers at the bar at the same time. I would have totally drank that margarita had he not seen him doing that. I decided to skip the margarita because of the high chance of CC

If you're going to continue to push for a diagnosis stay on gluten! A break could lead to a false negative. It's a lot harder to go off it and then go back on...

I still prefer steaming, but I wash my white rice throughly. I purchase California rice which has a lower level of arsenic. Moderation is key to most everything! ?

I eat pretty much grain free just fine, I eat fats instead. But on a side note I posted some specialty and grain free options as of late in the food alternative page where I list companies and food product alternatives. I honestly just welcomed bread back into my life, I found a company that makes grain free bread out of nut flours. Given you have to toast the dang bread to use it well but seems to work decently. Pasta there are carb free versions out there, and there are ones made with quinoa, buckwheat, or other grains, I even know one company that makes nut flour based ones. You can get these gluten-free options and avoid the rice. As to levels of arsenic they do test foods for these, and all should be safe, the trace amounts and the sheer amount you would have to eat to get effected is staggering, a bit of rice will not hurt you regardless if your concerned I know gluten-free watchdog does arsenic testing on products you could check and find the "safest ones" for your concerns.

I've forgotten them, just remember the good stuff. Weekends in Baja or Vegas or up Pacific highway to see the Redwoods and Frisco. Watching the sunrise at Mount Soledad and watching it drop into the Pacific in the evening. Carne Asada Burritos on Garnet* Solana beach ale* Gorgeous women entranced by my exotic accent, humboldt county weed, raves at the romper room, *1.99 are you out of your mind Denny Breakfasts, Christmas on the beach, *Beers in the gaslamp quarter. I need one of these * which by the power of my imagination have magically become gluten free AANNNYWAAY... Arsenic in rice. Yeah.