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Parkinson’s Patient with Celiac Disease Makes Dramatic Recovery on Gluten-free Diet

Celiac.com 09/29/2014 - Can a gluten-free diet lead to dramatic improvement of Parkinsonian symptoms in patients with celiac disease?

Image: Wikimedia Commons.In the January issue of the the Journal of Neurology, researchers Vincenzo Di Lazzaro, Fioravante Capone, Giovanni Cammarota, Daniela Di Giuda, and Federico Ranieri report on the case of a man who saw a dramatic improvement of Parkinsonian symptoms after gluten-free diet.

The researchers are affiliated with the Department of Neurosciences at the Institute of Neurology, Campus Bio-Medico University in Rome, Italy.

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This case is interesting because it supports a growing body of research that indicates that, in some cases, gluten toxicity might adversely impact the nervous system, producing symptoms identical to classical Parkinson’s disease.

The man in question was a 75-year-old Parkinson’s disease patient with silent celiac disease saw major improvements in his symptoms after a 3-month long gluten-free diet.

Noting the positive results in this patient, and the fact that celiac disease often manifests with only neurological symptoms, even in older patients, the researchers are calling for a deeper exploration to determine if there are higher rates of celiac disease in people afflicted with Parkinson’s disease, or the related multi-factorial neurodegenerative condition known as Parkinsonism.

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4 Responses:

 
S
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said this on
06 Oct 2014 2:52:05 PM PDT
I have to take a prescription, which is also used for Parkinsons, for restless legs. I have been getting B vitamin/magnesieum/Folic acid shots, which have really helped my legs. I tried it as the B vitamin shots were something that helped my Grandmother, who could not absorb B vitamins orally. They said she had pernicious anemia. This was 25-30 years ago and we had not heard of celiac, which my aunt also had. I also try to walk a few miles a day but don't always have time. So there is something related to reduced absorption with celiac. I also read somewhere that 34% of celiacs have restless legs. Maybe you could do an article on that?

 
Jefferson
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said this on
15 Oct 2014 6:49:07 PM PDT
Thanks for your comment! Our anti-spam settings prevent me from posting live links in this area, but do a search for 'restless leg' on celiac.com search bar, and you'll see a number of articles on the subject. I hope that helps.

 
J.polley
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said this on
07 Oct 2014 2:41:33 PM PDT
Unaware of this info. Also, do you have any data about gluten sensitivity as related to FODMAPS?
Thank you.

 
Jefferson
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said this on
15 Oct 2014 6:46:55 PM PDT
I can't paste links into this field for anti-spam reasons, but do a search for FODMAPS on celiac.com, and you'll see a number of articles on the subject.




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The only symptom I know of that is celiac for certain is dh, which must be diagnosed by a dermatologist.

I have both eoe and celiac and now that I have been gluten free for 18 months, my anemia is gone. It is good to get off the iron supliments because mine may have been the cause of my ulcers. It feels good to recover and heal! I may work my way down to fewer supliments and lots of feel great da...

Your daughter does not have a strong positive. I suspect that the GI might do as RMJ suggested which would be to load her up on gluten for six months and retest. On the other hand, with a diagnosed sibling and a very mild positive, your GI might recommend the endoscopy or run the test again to ...

I was diagnosed with celiac last year on an endoscopy looking for the cause of my anemia. At the time, my GI doc tested m for EoE and it was negative. Fast forward 11 months, I developed sudden heart burn, dysphagia out of the blue. My doc thinks it's EoE. Biopsy was last week and I am still wait...

No, the control test is to verify that she will react to that particular type of test. If she didn't, then certain of the bloods would not be applicable to her. They would be false negatives. As far as tests being weak positives, that's like being a little pregnant. A positive is a positive....