No popular authors found.
Ads by Google:

Categories

No categories found.


Get Celiac.com's E-Newsletter




Ads by Google:


Questions? Join Our Forum:
~1 Million Posts
& Over 66,000 Members!



SHARE THIS PAGE:
Celiac.com Sponsors:

Celiac Disease Drug Shows Some Promise, But Offers No Cure

Celiac.com 10/14/2014 - A new drug designed to prevent gluten uptake in the gut is showing some promise for the treatment of celiac disease.

Photo: Drs. Mayo Stamp--Wikimedia CommmonsThe drug, larazotide acetate, significantly reduced symptoms in a large double-blind, placebo-controlled trial. The drug prevents gluten uptake by closing tight junctions in the gastrointestinal (GI) tract.

The drug is intended to supplement, rather than replace, the gluten-free diet that makes up the standard celiac disease treatment. Specifically, the drug is designed to help patients who continue to experience symptoms despite efforts to avoid gluten, and will not allow celiac patients to eat gluten with impunity.

Ads by Google:

Some experts are cautioning celiac disease patients against high expectations. Joseph A. Murray, MD, of the Division of Gastroenterology and Hepatology at Mayo Clinic, in Rochester, Minnesota, said that, even if the drug is approved, it would not be a cure for celiac disease, but just another way to control symptoms for those already on a gluten-free diet.

Daniel Leffler, MD, director of research at the Celiac Center of Beth Israel Deaconess Medical Center, in Boston, called the news “exciting.” Dr. Leffler predicted that, if approved, the drug would be a useful addition to standard celiac disease treatment.

Source:

Celiac.com welcomes your comments below (registration is NOT required).












Related Articles



4 Responses:

 
Teresa

said this on
20 Oct 2014 3:07:43 PM PDT
That would be terrific but the side effects could be worse then the actual symptoms.

 
Laura

said this on
21 Oct 2014 4:32:34 PM PDT
What would be the long term effects of such a drug? I would love additional protection from the cross contamination that seems to stalk me, but the last thing I need to deal with are side effects or damage from another drug. Any word on that?

 
Jefferson
Rating: ratingfullratingfullratingfullratingfullratingfull Unrated ( Author)
said this on
23 Oct 2014 5:53:57 PM PDT
This drug is in early trials, so it's impossible to know about long-term effects. So far, the drug seems to be well-tolerated, but only extensive testing and time can answer your question with any certainty.

 
Irv
Rating: ratingfullratingfullratingfullratingfullratingempty Unrated
said this on
23 Oct 2014 8:09:06 AM PDT
Interesting.




Rate this article and leave a comment:
Rating: * Poor Excellent
Your Name *: Email (private) *:




In Celiac.com's Forum Now:


Hate to add more to your list but you may also want to look into Oral Allergy Syndrome. Mostly because how you describe almonds. Yes, it is another extensive list of foods for intolerance and allergies.

How long were you fully gluten free for Kirsty?

Hi Matt, So you say your hypoglycemia resolved going gluten free. In my case, it got worse trying to get off. Now my cortisol, progesterone and estrogens are low. The extreme stress from trying to cut it out of my diet offset my menstrual cycle. That leaves me with a lot of anxiety, blood su...

Thank you all for your great suggestions! Will take all of it on board

Dairy is a major issue with celiac, due to the enzymes to break it down being produced by the villi tips being mostly destroyed or damaged first. Eliminating for a few months may be critical. I might suggest digestive enzymes, I am taking Jarrow Enzymes at 2x the dose, Jarrow Bromelain, and somet...