No popular authors found.


Get Celiac.com's E-Newsletter

Categories

No categories found.







Ads by Google:


Questions? Join Our Forum:
~1 Million Posts
& Over 66,000 Members!



SHARE THIS PAGE:
Celiac.com Sponsors:

Bone Fracture Risk Double for Celiac Disease Patients

Celiac.com 11/17/2014 - There is a large body of data that show that celiac disease is associated with metabolic bone disorders, such as low bone mineral density. However, it is unclear whether this translates into an association between celiac disease and such hard clinical outcomes as bone fractures.

Photo: Wikimedia Commons--Thomas BjorkinA research team set out to systematically review and pool the data to better understand the nature of the relationship between celiac disease and the prevalence and incidence of bone fractures.

The research team included Katriina Heikkilä, Jo Pearce, Markku Mäki, and Katri Kaukinen. They are variously affiliated with the Departments of Internal Medicine at Seinäjoki Central Hospital and Tampere University Hospital, Finland, the School of Medicine at the University of Tampere, Finland, the Tampere Centre for Child Health Research at University of Tampere and Tampere University Hospital, Finland, and with the Division of Nutritional Sciences, School of Biosciences at the University of Nottingham in the United Kingdom.

For their study, they conducted a systematic search of Pubmed, Scopus, Web of Science and Cochrane Library in January 2014 for studies of celiac disease and bone fractures. They included observational studies of any design which compared bone fracture outcomes in individuals with and without celiac disease. Two investigators then independently gathered results from eligible studies.

Ads by Google:

A meta-analyses of case-control and cross-sectional studies showed that bone fractures were almost twice as common in individuals with a clinically diagnosed celiac disease as in those without celiac disease. A meta-analyses of prospective studies showed that celiac disease at baseline was associated with a 30% increase (95% CI: 1.14, 1.50) in the risk of any fracture and a 69% increase in the risk of hip fracture (95% CI: 1.10, 2.59).

Two studies of patients with high concentrations of celiac disease-specific autoantibodies, but no celiac disease diagnosis, produced contradictory findings. The results of this study suggest that people with clinically diagnosed celiac disease face a greatly increased risk of hip fractures, and of fractures in general.

Further research is needed to determine whether unrecognized celiac disease carries a similar risk of bone fractures.

Source:

Celiac.com welcomes your comments below (registration is NOT required).












Related Articles



1 Response:

 
Jill
Rating: ratingfullratingfullratingfullratingemptyratingempty Unrated
said this on
24 Nov 2014 4:31:26 PM PST
Does this continue to be the case if the patient is strictly adhering to the gluten-free diet? Does their risk lessen?




Rate this article and leave a comment:
Rating: * Poor Excellent
Your Name *: Email (private) *:




In Celiac.com's Forum Now:


If you have celiac would you eat their gluten free sandwiches? The place is full of gluten buns, the employees use new gloves yes...but they touch the gluten buns then by hand pull each ingredient from each bin CCing each bin of ingredients as they go.....the place is a CC nightmare and the logis...

You can make almond meal, or coconut porridge, there are some instant paleo porridge ready to go grain free ones....you can also use Miracle Rice blended in to give it oatmeal texture. If you miss flap jacks look up coconut flour ones if you want a mix look up Simple Mills Pancakes mix it is grai...

Ah ok, the bloating was fairly extreme and immediate.. which is quite unusual for me as normally there is a 24hr delay. Maybe I just overloaded my system.

Thanks for all the replies everyone - its very useful to have the support, particularly as my gp today said 'a tiny but if gluten three times won't cause an upst stomach for weeks' I just wanted to print off the entire forum for him to read!!

Subway announces gluten-free buns at all stores in Canada. But only for a limited time? Is the company trolling us? View the full article