No popular authors found.
Ads by Google:

Categories

No categories found.


Get Celiac.com's E-Newsletter





Ads by Google:


Follow / Share


  FOLLOW US:
Twitter Facebook Google Plus Pinterest RSS Podcast Email  Get Email Alerts
SHARE:

Popular Articles

No popular articles found.
Celiac.com Sponsors:

Metabolic Syndrome in Patients with Celiac Disease on a Gluten-free Diet

Celiac.com 04/06/2015 - Several studies have shown that many patients with celiac disease experience changes in body weight after starting a gluten-free diet, but researchers still don't have much data on rates of metabolic syndrome in this population.

Photo: CC--Samantha MarxA team of researchers recently set out to assess rates of metabolic syndrome in patients with celiac at diagnosis, and at one year after starting gluten-free diet. The research team included R. Tortora, P. Capone, G. De Stefano, N. Imperatore, N. Gerbino, S. Donetto, V. Monaco, N. Caporaso, and A. Rispo. They are affiliated with the Department of Clinical Medicine and Surgery, University Federico II of Naples, Naples, Italy, or with the Department of Education and Professional Studies, King's College London, London, UK.

For their study, the team enrolled all consecutive patients with newly diagnosed celiac disease who were referred to their third-level celiac disease unit. For all patients the team collected data on waist circumference, BMI, blood pressure, HDL cholesterol, triglycerides, and blood sugar levels.

The team diagnosed metabolic syndrome according to the International Diabetes Federation (IDF) criteria for European countries. They reassessed rates of metabolic syndrome in patients after 12 months of gluten-free diet.

Ads by Google:

The team assessed ninety-eight patients with celiac disease, two (2%) who fulfilled the diagnostic criteria for metabolic syndrome at diagnosis, and 29 patients (29.5%) after 12 months of gluten-free diet (P < 0.01; OR: 20).

After 1 year on a gluten-free diet, the team compared the patient data to baseline, with respect to metabolic syndrome sub-categories. They found 72 vs. 48 patients exceeded waist circumference cut-off (P < 0.01; OR: 2.8); 18 vs. 4 patients had high blood pressure (P < 0.01; OR: 5.2); 25 vs. 7 patients exceeded glycemic threshold (P = 0.01; OR: 4.4); 34 vs. 32 patients with CD had reduced levels of HDL cholesterol (P = 0.7); and 16 vs. 7 patients had high levels of triglycerides (P = 0.05).

The results of this study show that celiac disease patients have a high risk of developing metabolic syndrome 1 year after starting a gluten-free diet.

To address this, the research team recommends an in-depth nutritional assessment for all patients with celiac disease.

Source: 

Celiac.com welcomes your comments below (registration is NOT required).












Related Articles



3 Responses:

 
Iwona
Rating: ratingfullratingfullratingfullratingfullratingempty Unrated
said this on
13 Apr 2015 11:57:34 AM PDT
That sounds exactly like me...keeping in shape was so much easier when I ate gluten. Now I need to really watch out for what I eat even if I practice a lot of sport... And whenever I have a short breakout in my diet (1-2 days and with not a lot of gluten - I don't jump suddenly on a loaf of bread) I suddenly loose all the water in my organism and get much leaner.
BTW. the article would be even better if it had more factual information about the study.

 
coloradosue
Rating: ratingfullratingfullratingfullratingemptyratingempty Unrated
said this on
14 Apr 2015 3:18:52 AM PDT
Since being diagnosed with CD in 2004 to this year, I have gained 40 lbs. I also have Fibromyalgia, osteoarthritis in the L4and L5 that requires shots every 3 to 4 months. My doctors as well as others that politely suggest I should lose weight. Wish I could! These medical issues interfere every hour of every day by increasing pain levels that at times leaves me in bed or living room couch. I'm buying clothes from goodwill just to have something to wear. I am just sick and may I dare say... TIRED from hurting day in and day out. And taking pain meds which expensive. Which reminds me, time for mine.

 
Bonnie
Rating: ratingfullratingfullratingfullratingemptyratingempty Unrated
said this on
05 May 2015 9:36:35 AM PDT
I agree with Iwona -- the article would have been more helpful if it had more info about the study. I've gained almost 30 pounds since I was diagnosed and my Dr says, "Eat less and exercise more!" HAH! I'm at my wits end! I've tried lo-carb and Paleo diets, they are OK, but I still don't lose!




Rate this article and leave a comment:
Rating: * Poor Excellent
Your Name *: Email (private) *:




In Celiac.com's Forum Now:


The only symptom I know of that is celiac for certain is dh, which must be diagnosed by a dermatologist.

I have both eoe and celiac and now that I have been gluten free for 18 months, my anemia is gone. It is good to get off the iron supliments because mine may have been the cause of my ulcers. It feels good to recover and heal! I may work my way down to fewer supliments and lots of feel great da...

Your daughter does not have a strong positive. I suspect that the GI might do as RMJ suggested which would be to load her up on gluten for six months and retest. On the other hand, with a diagnosed sibling and a very mild positive, your GI might recommend the endoscopy or run the test again to ...

I was diagnosed with celiac last year on an endoscopy looking for the cause of my anemia. At the time, my GI doc tested m for EoE and it was negative. Fast forward 11 months, I developed sudden heart burn, dysphagia out of the blue. My doc thinks it's EoE. Biopsy was last week and I am still wait...

No, the control test is to verify that she will react to that particular type of test. If she didn't, then certain of the bloods would not be applicable to her. They would be false negatives. As far as tests being weak positives, that's like being a little pregnant. A positive is a positive....