No popular authors found.
Ads by Google:

Categories

No categories found.


Get Celiac.com's E-Newsletter





Ads by Google:


Follow / Share


  FOLLOW US:
Twitter Facebook Google Plus Pinterest RSS Podcast Email  Get Email Alerts
SHARE:

Popular Articles

No popular articles found.
Celiac.com Sponsors:

How Gluten Impairs Drug Absorption

Celiac.com 05/13/2015 - In addition to being a common ingredient in many commercial food products, gluten is also used in numerous medications, supplements, and vitamins, often as an inert ingredient known as an excipient.

Photo: CC--Jinx!Because chronic gluten-related inflammation and damage impairs absorption of nutrients, and likely causes malabsorption of oral medications, it is extremely important for people with celiac disease to review the nutrition labels of all foods and beverages, as well as the package inserts (PI) for information about gluten content.

Most oral medications depend on absorption through the small intestine via passive diffusion. GI-tract damage may shift this diffusion process into systemic circulation, which can result in increased or decreased absorption, depending on the drug molecules.

Since drug molecules have varying and unique chemical properties, it is hard to determine the exact means of drug absorption in celiac patients, and also hard to determine the impact of celiac disease on drug absorption.

Ads by Google:

Based on their molecular properties, researchers suspect the absorption of a number of drugs is impaired by gluten sensitivity.

These drugs include: acetaminophen, aspirin, indomethacin, levothyroxine, prednisolone, propranolol, and certain antibiotics.

For these reasons, it is important for doctors to monitor serum drug levels for medications with narrow therapeutic indexes in people with celiac disease. If you have celiac disease, please let your doctor know before you take these drugs.

Source:

Celiac.com welcomes your comments below (registration is NOT required).












Related Articles



Comments




Rate this article and leave a comment:
Rating: * Poor Excellent
Your Name *: Email (private) *:




In Celiac.com's Forum Now:


Yeah I tend to have Mr. Hyde come out with gluten exposure. Honestly he was not present with my last few minor issues....anyway. Plenty of fluids, bone broths if she can do them. whole food soups. Avoid processed foods, have more whole foods and greens. Green and herbal teas can help. NOTE there ...

My daughter (6) was recently glutened by a friend of the family. She gave her a drink that didn't have gluten in it but was made at a factory that has gluten contamination. She recently just started a brand new school because we hadn't diagnosed her allergies yet and she has severe behavior pr...

I'm so sorry. Nursing school is rigorous enough on top of all this stress. And, kudos to you for cooking regularly even in school. I've been through a lot of school and I never managed that. I can see how it feels hopeless to try and change your roommate's behavior - almost like an insurmounta...

"Any Coeliac will tell you the most awkward time of the day for them is lunch" Ya just can't make stuff like this up. Lunchtime is awkward?

Shouldn't they be studying why celiacs who have been gluten-free for a year are still seropositive and having moderate to severe symptoms? It sounded like the pill was suppposed to be taken with meals that might have cc ? So why would they do a study where it's given with gluten-free meals?...