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How Gluten Impairs Drug Absorption

Celiac.com 05/13/2015 - In addition to being a common ingredient in many commercial food products, gluten is also used in numerous medications, supplements, and vitamins, often as an inert ingredient known as an excipient.

Photo: CC--Jinx!Because chronic gluten-related inflammation and damage impairs absorption of nutrients, and likely causes malabsorption of oral medications, it is extremely important for people with celiac disease to review the nutrition labels of all foods and beverages, as well as the package inserts (PI) for information about gluten content.

Most oral medications depend on absorption through the small intestine via passive diffusion. GI-tract damage may shift this diffusion process into systemic circulation, which can result in increased or decreased absorption, depending on the drug molecules.

Since drug molecules have varying and unique chemical properties, it is hard to determine the exact means of drug absorption in celiac patients, and also hard to determine the impact of celiac disease on drug absorption.

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Based on their molecular properties, researchers suspect the absorption of a number of drugs is impaired by gluten sensitivity.

These drugs include: acetaminophen, aspirin, indomethacin, levothyroxine, prednisolone, propranolol, and certain antibiotics.

For these reasons, it is important for doctors to monitor serum drug levels for medications with narrow therapeutic indexes in people with celiac disease. If you have celiac disease, please let your doctor know before you take these drugs.

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We freeze portions in a regular freezer zip lock bag.

That sounds good. Do you have a machine that seals without air or do you just use bags? Is it possible to buy bags only? I remembered the other type of froz food I sometimes get - Saffron Road.

You can always check to see how long the lab order lasts, if you'd like to continue eating gluten longer.

Might be something else in there, perhaps he ate something else with gluten, something was mixed in the chips, the chips were flavored or in a snack mix with pretzels. I get that way with gluten, but the last 2 times the gut issues render me unable to argue like that but I do go Mr. Hyde like =. ...

I hate to say it and be Mr. Negative ass here. But I had this exact same thought about having kids, I do not wish any kids I have to have my AI issues, and decided I would wait a few decades if need be for the new gene editing things they are working on so we can have them changed. Call me crazy.