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Celiac Disease Problems You Want to Avoid

Celiac.com 06/05/2015 - For anyone with celiac disease, following a lifelong gluten-free diet has been shown to relieve symptoms, and in celiac patients it has been shown to normalize serologic markers of celiac disease, and to restore damaged intestinal villi.

Photo: CC--MeridicanNot following a gluten-free diet, on the other hand, can result in serious complications associated with malabsorption.

When celiac disease goes untreated, when people who have celiac disease refuse to follow a gluten-free diet, chronic gluten-related inflammation and damage impairs absorption of nutrients, and likely causes malabsorption of oral medications.

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Malabsorption resulting from damaged mucosa can lead to:

  1. Nutritional deficiencies of the fat-soluble vitamins A, D, E, and K, as well as the B vitamins, thereby diminishing the absorption of iron, calcium, and folic acid. Nutritional deficiencies can lead to:
  2. Iron-deficiency anemia refractory to oral iron supplementation, and potentially osteoporosis and osteopenia due to bone loss due to decreased calcium and vitamin D absorption. A combination of nutritional deficiencies and the damaging effects of systemwide chronic inflammation can cause:
  3. Reproductive abnormalities, such as delayed puberty, secondary amenorrhea, infertility, or decreased fertility. Adverse immune responses to gluten ingestion can trigger other common manifestations, such as:
  4. Dermatitis herpetiformis, a papulovesicular rash. Beyond that, problems can include:
  5. Fractures secondary to low bone mineral density. In some cases, untreated celiac disease can lead to intestinal malignancies such as:
  6. Intestinal T-cell lymphomas.
  7. Small-bowel adenocarcinoma.
  8. Esophageal cancer.
  9. B- and T-cell non-Hodgkin lymphomas.

Rapid, proper diagnosis and effective treatment of celiac disease are crucial to preventing a cascade of related problems that can further impair diagnosis, and cause irreparable damage to patient health.


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2 Responses:

 
carol
Rating: ratingfullratingfullratingfullratingfullratingfull Unrated
said this on
08 Jun 2015 4:11:44 PM PST
Found that this enforces the need to stay gluten free.

 
Lorri Devlin, BSN, MS, RN
Rating: ratingfullratingfullratingfullratingfullratingempty Unrated
said this on
11 Jun 2015 7:09:16 AM PST
Kudos for spreading the word about the harmful effects of gluten for celiacs. My dad died of the disease before anyone realized gluten had caused a lifetime of illness. He was frail, had fungal infection in his lungs, depression, neuropathy, herpetic dermatiformis and failure to thrive. My sister and I were diagnosed in our 40's. By then I had vitamin D deficiency, had been hospitalized four times with perforated intestines, and had undergone a colectomy. Since being GF, I'm completely healthy. As a registered nurse I now make sure to assess for food intolerance whenever I see a patient with rashes, asthma, or unexplained fatigue.




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Some people, like me, never get a positive on the TTG (even on follow-up Testing) and I stated that some celiacs (10%) have negative tests results period. Your doctor is doing the colonoscopy. Ask him if he is going into the small intestine via that route.

Yep. Initially I had the full panel. DGP was the only positive and it's the only one my doctor orders now.

Well I wish mine was dia. earlier, I got all kinds of other food issues, and other auto immune disease that came up as complications. If you deal with and change over now you can prevent a even more limited diet. I was running a bucket list thinking I was going to die before my dia. I had slight ...

So, do they just test your DGP like they just test my TTG?

The only test I have had done is the TTG because that's what I had done initially after taking matters into my own hands and going to my local health fair. Celiac is so common they do that screening at our health fair. My number was so high that my doctor didn't order other labs and went straight...