No popular authors found.
Ads by Google:

Categories

No categories found.


Get Celiac.com's E-Newsletter





Ads by Google:


Follow / Share


  FOLLOW US:
Twitter Facebook Google Plus Pinterest RSS Podcast Email  Get Email Alerts
SHARE:

Popular Articles

No popular articles found.
Celiac.com Sponsors:

Do Perinatal Risk Factors Influence Development of Celiac Disease in Children?

Celiac.com 06/12/2015 - Some researchers have suspected that certain prenatal and perinatal factors might affect risk for development of celiac disease, but there is very little data. With this in mind, a team of researchers set out to determine if any prenatal and perinatal factors might affect risk for development of celiac disease in children.

Photo: CC--BeshefTheir team assessed the association of fetal growth, birth weight, and mode of delivery with development of celiac disease within the Norwegian Mother and Child (MoBa) Cohort Study. The research team included Louise Emilsson, Maria Christine Magnus, and Ketil Størdal. They are variously affiliated with the Primary Care Research Unit, Vårdcentralen Värmlands Nysäter, County Council of Värmland, Sweden, the Department of Health Management and Health Economy, Institute of Health and Society, University of Oslo, Oslo, Norway, the Division of Epidemiology, Norwegian Institute of Public Health, Oslo, Norway, and the Paediatric Department, Ostfold Hospital Trust, Fredrikstad, Norway.

To make their determination, the team used the MoBa cohort, which contains pregnancy information on 95,200 women and data on their 114,500 children. The information was collected in Norway from 1999 through 2008; it is linked to the Norwegian Medical Birth Registry. The team used the National Patient Registry and women’s responses to MoBa questionnaires to identify women and children with celiac disease.

The team calculated odds ratios (ORs) for celiac disease by using a multivariable logistic regression model, adjusting for maternal celiac disease, sex of children, and children’s age (model 1). In model 2, they adjusted for age of gluten introduction and duration of breastfeeding.

Ads by Google:

The team identified 650 children with celiac disease and 107,828 controls in the MoBa database. They found no connection between birth weight or height with celiac disease, including for children who were born small for gestational age.

They found no celiac disease connection based on mode of delivery (cesarean section, model 1: OR, 0.84; 95% confidence interval [CI], 0.65–1.09, and model 2: OR, 0.83; 95% CI, 0.63–1.09). They did find that maternal celiac disease, adjusted for age and sex of the children and type 1 diabetes were associated with development of celiac disease in children, whereas maternal type 2 diabetes and gestational diabetes were not.

Their analysis of the Norwegian MoBa cohort shows that development of celiac disease in children is significantly associated with sex of the child, maternal celiac disease, and type 1 diabetes, but not with gestational development.


Source:

Celiac.com welcomes your comments below (registration is NOT required).












Related Articles



Comments




Rate this article and leave a comment:
Rating: * Poor Excellent
Your Name *: Email (private) *:




In Celiac.com's Forum Now:


If I were you I would get back on gluten and get the full celiac blood test done. It includes TTG IGA and IGG, DGP IGA and IGG, EMA, and IGA. You need to be consuming gluten for a negative to be valid. It only takes one positive result to get a gastroenterologist to do the endoscopy/biopsies. You...

I'm a 28 year old female who has battled a mystery illness for 8 months now. It started with a trip to South America last November, when I was in perfect health. I spent 8 days there, and on the last day both my traveling companion and I got what we thought was traveler's diarrhea. It only l...

I presented the exact same way as your daughter, only I was 46 years old at the time. I also have a double DQ-2 gene and that means it will be more severe...which you already know and I already know, from experience. My weight and height were about the same and I was down to 92 pounds at diagn...

I have a very similar if not worse bipoloar mind trips to aspartame as gluten complete Mr. Hyde yelling, punching walls, snapping 180 difference in personality.

HA, just following up Still feeling groovy and remember faces.