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  • Celiac.com Sponsored Post
    Celiac.com Sponsored Post

    GliadinX Breaks Down Gluten in the Gut

    Reviewed and edited by a celiac disease expert.
    GliadinX Breaks Down Gluten in the Gut -

    GliadinX is a dietary supplement with the highest concentration of AN-PEP, Prolyl Endopeptidase (Aspergillus Niger), the most effective enzyme proven to break down gluten in the stomach. This high potency enzyme formulation is specifically designed to break down gliadin, and unlike other enzyme formulas that claim to do the same, there is a growing body of research that backs up the effectiveness of GliadinX (see Sources below).

    GliadinX does not prevent and is not a cure for celiac disease, however, extensive scientific research has been conducted at multiple medical centers which has shown that it effectively breaks down gliadin into small, harmless fragments before it can reach the small intestine. GliadinX is perfect for celiacs who still want to eat outside of their home, and not have to worry about cross-contamination, and for those who are gluten sensitive and wish to continue eating gluten.

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    Quote

     

    12. Treatment of the Extra-Intestinal Manifestations of CD

    the only one that is currently on the market is the gluten-specific enzyme, GliadinX (AN-PEP). Unfortunately, it is only capable of detoxifying 0.2 g of gluten or roughly that of 1/8 of a slice of gluten-containing bread. For this reason, it should only be used as an adjunct to the GFD when there are concerns for accidental gluten contamination and in an effort to ameliorate symptoms, not as a replacement for the GFD.

     

    Sources:



    User Feedback

    Recommended Comments

    Guest Bonnie

    Posted

    Where can GliadinX be purchased? Thank you for your response.

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    Guest Meaghan

    Posted

    I can't be sure...but I think this product actually works. I went to a BBQ where they were cooking burgers on the grill. I brought tin foil to put on the grill to at least safe guard myself. However, the guy cooking was using the same spatula for everything, putting the burgers directly onto the buns. Needless to say, I'm sure there was cross contamination going on. I popped 2 of these pills and I didn't react at all. It could just be that there wasn't any cross contamination...but it seems promising!

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    Guest Ryan

    I just wanted to point out that this article says that GliadinX/AN-PEP helps with gluten sensativity, a claim which is contradicted by the article posted March 2020 about enzymes for breaking down gluten. 

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    docaz
    19 hours ago, Guest Ryan said:

    I just wanted to point out that this article says that GliadinX/AN-PEP helps with gluten sensativity, a claim which is contradicted by the article posted March 2020 about enzymes for breaking down gluten. 

    GliadinX/AN-PEP does not have any effect on celiac disease or gluten sensitivity because these are systemic diseases but it is very effective in breaking down the gliadin molecule and that's how it helps celiac patients and some gluten sensitive people (only the ones related to the gliadin molecule) maintaining a gluten-free diet. There is no contradiction at all because there is a big difference if something has an effect on the body or on the ingested food. GliadinX has no effect on the body and only on the food. It is clearly established that a gluten-free diet without any cross-contamination is very unrealistic. We can see just on this site alone how many people who are very careful, report cross-contamination or accidental gluten-ingestion. GliadinX breaks down the contaminants in the stomach into small harmless fragments but unlike a vaccine for example, it does not change the underlying disease and until we will have a cure that will change the underlying disease, this is the best we have so far and lots of research shows that it is very good. There are several people on this site who dispute that but are only either expressing their own opinion or referring to other opinions that are not based on any study because all studies with the exception of one study show how effective it is. The only study that is ambiguous is one in which celiac patients were challenged with gluten and AN-PEP was given. They did not have symptoms or got worse but the placebo did the same and this is because the study was much too short. 

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