No popular authors found.


Get Celiac.com's E-Newsletter

Categories

No categories found.







Ads by Google:


Questions? Join Our Forum:
~1 Million Posts
& Over 66,000 Members!



SHARE THIS PAGE:
Celiac.com Sponsors:

Peptide Discovery Gets To The Guts Of Celiac Disease

July 2000 - Chemistry In Britain
Summarized by Linda Blanchard

Ads by Google:

Celiac.com 01/10/2001 - The article states that Oxford physicians and scientists did an experiment in which celiac patients who were previously on a gluten-free diet were fed a series of human-made peptides that are copies of portions of the peptide chains that are found in the gliadin portion of wheat. The hope was that by feeding those in the study overlapping partial chains, and then testing their blood for T-cells afterward, they could find which specific portion of the wheat protein set off the immune reaction in celiacs.

One single peptide did trigger the reaction. Now that it has been identified, it is hoped that some solutions to the problems caused by celiac disease may become available. Two approaches seem to involve "turning off" the reaction -- its thought that offering a megadose of the particular peptide might turn the immune reaction off. Another method would involve offering a peptide that was very similar to the offending piece of wheat protein -- but just enough different that it might "turn off" the reaction.

Another possibility is, of course, genetically modified wheat. It should be possible for scientists to develop a wheat that has a different peptide in the place of the offender, which would hopefully look, taste, and act as wheat does in normal baking without triggering celiac reactions.

Celiac.com welcomes your comments below (registration is NOT required).












Related Articles



Comments




Rate this article and leave a comment:
Rating: * Poor Excellent
Your Name *: Email (private) *:




In Celiac.com's Forum Now:


Ummm what does this have to do with our gluten free community? Good point about giving stuff you would need to the community and all....but has nothing to do with celiac disease really, just mentions you should not give gluten free bread to a homeless persons that does not need it stating that it...

In Austin, Wildwood Bakehouse and Wilder Wood Restaurant are totally gluten free. I had the chicken fried steak and gravy and onion rings!!! Awesome!!!

If you yourself have Celiac's disease, you probably shouldn't give gluten-free sandwiches to the homeless, because they're disgusting. Your male neighbor doesn't need tampons. That sort of reasoning should be applied. But you must always remember that the Gospel requires you to treat other people...

Hi there I have this exact same thing.. however I don?t have celiac that I know of.. I found this when google searching for what the heck is wrong with my face. I was wondering if you ever found out.. or if it just went away. Thanks

I have read the newbie 101 and have been careful about reading labels. I'm the only one that's gluten free in my household, so they could be contaminating me. I was eating gluten for 6 weeks after my blood test because it took that long to get an official diagnosis and my GP told me to still be e...