Celiac Disease and Gluten-Free Diet Support
- Questions? Join our forum: Nearly 1 MILLION POSTS, and over 62,000 MEMBERS!
Follow / Share
|Get Email Alerts|
- Safe Gluten-Free Food List (Safe Ingredients)
- Unsafe Gluten-Free Food List (Unsafe Ingredients)
- Gluten-Free Alcoholic Beverages
- Celiac Disease Symptoms
- The Gluten-Free Diet 101 - A Beginner's Guide to Going Gluten-Free
- Interpretation of Celiac Disease Blood Test Results
- Is Buckwheat Flour Really Gluten-Free?
Reaction to a Gluten Challenge
The following post if from Karoly Horvath, M.D., khorvath@POL.NET, who is one of the two directors of the celiac center at University of Maryland in Baltimore.
Q: Does that mean I could be getting damage without knowing it because I have no obvious reaction?
A: Based on our studies a typical (biopsy proven flat mucosa, proved immune reactions to gluten) gluten intolerant patient does not react immediately with clinical symptoms for a gluten challenge (J Pediatr Gastroenterol Nutr 1989, 9:176-180). However, ingestion of GRAMS OF GLUTEN causes several changes in the intestine.
- There is an accumulation of inflammatory cells
- One cell type -so called mast cells- releases factors which factors in long-term damage the villi and they also release a factor which;
- Increases the permeability -leakiness- of the intestine, which is a temporarily change after a single ingestion but may be permanent after repeat dietary mistakes.
Karoly Horvath, M.D., Ph.D., Baltimore
Celiac.com welcomes your comments below (registration is NOT required).
Endoscopic Biopsy Technique in the Diagnosis of Celiac Disease: One Bite or Two?
Getting high-quality biopsy specimens is key to making accurate celiac disease diagnoses.... [READ MORE]
Metabonomic Signature of Celiac Disease
Metabolites are small–molecule products of biochemical processes in the body’s cells.... [READ MORE]
Effect of Treatment on Bone Mass, Mineral Metabolism, and Body Composition in Untreated Celiac Patients
Authors: Mautalen, Carlos, M.... [READ MORE]
The Standard Definition of Celiac Disease
excerpt was taken from the November 24, 1996 edition of the The Sprue-nik
Press, which is published by the Tri-County Celiac Sprue Support Group
(TCCSSG), a local chapter of CSA/USA located in southeast Michigan.... [READ MORE]
In 1994 I was diagnosed with celiac disease, which led me to create Celiac.com in 1995. I created this site for a single purpose: To help as many people as possible with celiac disease get diagnosed so they can begin to live happy, healthy gluten-free lives. Celiac.com was the first site on the Internet dedicated solely to celiac disease. In 1998 I foundedÂ The Gluten-Free Mall, Your Special Diet Superstore!, and I am the co-author of the book Cereal Killers, and founder and publisher of Journal of Gluten Sensitivity.View all articles by Scott Adams
In Celiac.com's Forum Now:
Celiac.com Celiac Disease & Gluten-Free Diet Forum - All Activity