No popular authors found.
Ads by Google:

Categories

No categories found.


Get Celiac.com's E-Newsletter





Ads by Google:


Follow / Share


  FOLLOW US:
Twitter Facebook Google Plus Pinterest RSS Podcast Email  Get Email Alerts
SHARE:

Popular Articles

No popular articles found.
Celiac.com Sponsors:

Histologic Follow-up of People With Celiac Disease on a Gluten-free Diet: Slow and Incomplete Recovery

Wahab PJ, Meijer JW, Mulder CJ.

Department of Gastroenterology and Hepatology, Rijnstate Hospital Arnhem, The Netherlands.

Ads by Google:

Am J Clin Pathol 118(3):459-463, 2002

Celiac.com 10/28/2002 - The following study strongly supports follow-up care and testing for people with celiac disease. As the study found, over 10% of people with diagnosed celiac disease have still not fully recovered even after five years of treatment.
To assess histologic recovery in response to gluten withdrawal in celiac disease, 158 patients seen in our hospital during a 15-year period underwent follow-up small intestine biopsies (SIBs) within 2 years after starting a gluten-free diet; further SIBs were done if villous atrophy was present. A modified Marsh classification was used (IIIA, partial villous atrophy; IIIB, subtotal villous atrophy; IIIC, total villous atrophy). Of patients with Marsh IIIA, IIIB, or IIIC lesions, histologic remission was seen in 65.0% within 2 years, 85.3% within 5 years, and 89.9% in long-term follow-up. Eleven patients (7.0%) with persisting (partial) villous atrophy had symptoms and signs of malabsorption and were considered to have refractory celiac disease; 5 of them developed an enteropathy-associated T-cell lymphoma. Children recovered up to 95% within 2 years and 100% in the long-term. Histologic recovery in celiac disease after starting a gluten-free diet takes time and is incomplete or absent in a substantial subgroup of patients (10.1% villous atrophy after 5 years). Systematic follow-up of patients with celiac disease and the malabsorption syndrome and secondary complications is needed.

Celiac.com welcomes your comments below (registration is NOT required).












Related Articles



Comments




Rate this article and leave a comment:
Rating: * Poor Excellent
Your Name *: Email (private) *:




In Celiac.com's Forum Now:


Sorry to hear about your no meat, Ennis. It sucks his celiac disease messes with people in different ways. Matt I was living on sweet potatoes but now they bloat me, which is odd. Avocado's would be to much fat, I think. I'm three weeks in today, and the past few days my C has improved....

I hope you don't have to wait too long for the results. A false negative is always possible since we have a lot of intestine but it sounds like you have a good doctor who took lots of biopsies. Since she had a high positive it would be a good idea for her to do the diet strictly for a few months...

I did not see anyone give ideas about milk-based gravies or sauces yet, but I found a great solution by trial and error because so many recipes I love call for "cream of mushroom" or "cream of chicken" soup. Just melt a little butter with diced onion and put in some rice flour with a bit of milk ...

So my type 1 daughter had her biopsy today and the gi afterwards noticed some redness/inflammation (gastritis?) but also saw the villi. I guess I was expecting that with her blood test result of her transglutinminase ttg iga of over 100 that she would definitely see some damage. Her symptoms se...

Avocados are packed with good fats. Aldi and Lidl often have them on offer. You may be able to tolerate sweet potatos if you're looking for a carb. They're better for you than potatoes, lower glycaemic index and more nutrients. Ask the pharmacy if they can order in the folic acid varia...