No popular authors found.


Get Celiac.com's E-Newsletter

Categories

No categories found.







Ads by Google:


Questions? Join Our Forum:
~1 Million Posts
& Over 66,000 Members!



SHARE THIS PAGE:
Celiac.com Sponsors:

Wheat Starch-containing Gluten-free Flour Products in the Treatment of Coeliac Disease and Dermatitis Herpetiformis. A Long-term Follow-up Study.

Scand J Gastroenterol 1999 Feb;34(2):163-9
PMID: 10192194, UI: 99206412
Authors: Kaukinen K, Collin P, Holm K, Rantala I, Vuolteenaho N, Reunala T, Maki M
Dept. of Medicine, Tampere University Hospital, Finland.

(Celiac.com 05/14/2000)

SPECIAL NOTE: European Codex Alimentarius quality wheat starch was used in this study.

Ads by Google:

BACKGROUND: We investigated whether wheat starch-based gluten-free products are safe in the treatment of gluten intolerance.

METHODS: The study involved 41 children and adults with coeliac disease and 11 adults with dermatitis herpetiformis adhering to a gluten-free diet for 8 years on average. Thirty-five newly diagnosed coeliac patients at diagnosis and 6 to 24 months after the start of a gluten-free diet and 27 non-coeliac patients with dyspepsia were investigated for comparison. Daily dietary gluten and wheat starch intake were calculated. Small bowel mucosal villous architecture, celiac disease3+, alphabeta+, and gammadelta+ intraepithelial lymphocytes, mucosal HLA-DR expression, and serum endomysial, reticulin, and gliadin antibodies were investigated. RESULTS: Forty of 52 long-term-treated patients adhered to a strict wheat starch-based diet and 6 to a strict naturally gluten-free diet; 6 patients had dietary lapses. In the 46 patients on a strict diet the villous architecture, enterocyte height, and density of alphabeta+ intraepithelial lymphocytes were similar to those in non-coeliac subjects and better than in short-term-treated coeliac patients. The density of gammadelta(+)cells was higher, but they seemed to decrease over time with the gluten-free diet. Wheat starch-based gluten-free flour products did not cause aberrant upregulation of mucosal HLA-DR. The mucosal integrity was not dependent on the daily intake of wheat starch in all patients on a strict diet, whereas two of the six patients with dietary lapses had villous atrophy and positive serology.

CONCLUSION: Wheat starch-based gluten-free flour products were not harmful in the treatment of coeliac disease and dermatitis herpetiformis.

Celiac.com welcomes your comments below (registration is NOT required).












Related Articles



Comments




Rate this article and leave a comment:
Rating: * Poor Excellent
Your Name *: Email (private) *:




In Celiac.com's Forum Now:


It sounds like your hives resolved. I had a six month bout with them. Antihistamines really helped. My doctors are not sure if Mast Cell or autoimmune is the root cause.

My kid has Raynauds. It freaks her classmates out. She wears shoes and wool socks all year round and we live in a warm state. It is autoimmune. She manages it by layering, turning up the heat, use lots of blanket throws. I have Hashimoto?s and celiac disease. So, having multiple autoi...

Well, you do need to replace some things because they are too porous or damaged to remove gluten. Things like old wooden spoons, scratched non-stick pans, toaster, colander, sponges, etc. Honestly, the list is long, so try getting a few celiac books at the library or Amazon. Consider reading t...

When I woke up from my Endoscopy and was told I definitely had celiac disease the first thing I asked my doctor was do I need to get all new kitchen stuff? He assured me that I did not, and as long as my pots and pans and everything else was washed after being used to cook gluten I would have no ...

They have all given you good advice. Like Ennis_Tx said this is not medical advice. Just some observations. Ennis_Tx mentioned already a good B-complex. But people who have Perncious Anemia low B-12 have "Pens and Needles' feeling in their extremities. Mine was much more ...