No popular authors found.
Ads by Google:

Categories

No categories found.


Get Celiac.com's E-Newsletter





Ads by Google:


Follow / Share


  FOLLOW US:
Twitter Facebook Google Plus Pinterest RSS Podcast Email  Get Email Alerts
SHARE:

Popular Articles

No popular articles found.
Celiac.com Sponsors:

Antibodies to Oat Prolamines Found in Children with Celiac Disease

Scand J Gastroenterol. 2003 Jul;38(7):742-6

Ads by Google:

Celiac.com 08/25/2003 – A recent study published in the July edition of the Scandinavian Journal of Gastroenterology demonstrates that avenin oat prolamines can be detected at higher levels in children with celiac disease compared to those without CD. The researchers prepared a crude avenin extract using an ethanol and salt solution, and used it as an antigen in a three step ELISA test. The blood of 81 children, including 34 with celiac disease, were analyzed for both IgA and IgG antibodies to avenin and gliadin. The researchers found that: Children with coeliac disease on a normal diet had significantly higher levels of antibodies to avenin, both IgG and IgA, than reference children (P < 0.001) and the levels correlated positively with gliadin antibodies, especially of IgA-type (r = 0.798). Both anti-avenin and anti-gliadin antibodies were only absorbed by the corresponding protein.

The researchers conclude: Children with coeliac disease have antibodies to oat proteins at significantly higher levels than reference children. The absorption test did not indicate a cross-reactivity between the prolamines of wheat and oats. The method will be employed for repeated sampling of anti-avenin antibodies during a prospective interventional study with a gluten-free diet supplemented with oats. An emphasis should be added to the last sentence, as it appears that they will now perform a study on celiac children who actually eat oats, and most other major studies of this type have shown no intestinal damage caused by the avenin oat prolamines in people with celiac disease. It is interesting that this study shows a different response to oats in those with celiac disease, but it remains to be seen if this response is actually harmful to celiacs.

Celiac.com welcomes your comments below (registration is NOT required).












4 Responses:

 
Kathie Bauer
Rating: ratingfullratingfullratingfullratingfullratingfull Unrated
said this on
14 Mar 2008 2:15:38 AM PDT
If my celiac 13 year old daughter eats oats daily she has bad stomach aches but if eaten just once a week, she has no symptoms.

 
sandy p
Rating: ratingfullratingfullratingfullratingfullratingfull Unrated
said this on
22 Jul 2008 11:56:08 AM PDT
My daughter can also eat oatmeal without any problems though seldom does except for homemade granola.

 
judy
Rating: ratingfullratingfullratingfullratingfullratingfull Unrated
said this on
01 Sep 2008 3:25:03 PM PDT
I miss oatmeal ? Is there anyway to be tested for the prolamines mentioned in this article . I stopped eating oatmeal in 1990 - as I finally realized my face and feet were reacting to the oatmeal - my feet and sometimes my face were swollen each morning after consuming oatmeal in the past week . I have celiac and Dermatitis Herpetiformis. The swelling was so bad I couldn't get my shoes on and as far as my face it could be so bad that my neighbors didn't recognize me.

 
marilyn mcmahon
Rating: ratingfullratingfullratingfullratingfullratingfull Unrated
said this on
25 May 2010 2:05:28 PM PDT
I have the same problem. I would love to try the assorted oatmeal they have out, but just getting cleared up by my great doctor after three years.




Rate this article and leave a comment:
Rating: * Poor Excellent
Your Name *: Email (private) *:




In Celiac.com's Forum Now:


Regular Rice Krispies in the US and Canada are not gluten free. They contain Barley Malt. See the below ingredients of the Rice Krispies in Canada... Ingredients: Rice, sugar, salt, corn and barley malt extract, Vitamins and minerals: iron, niacinamide, thiamine hydrochloride, choleca...

The GFCO was founded in 2005 by the Gluten Intolerance Group of North America (GIG) to offer independent certification to manufacturers of gluten-free products. GFCO certification is accredited to ISO 17065, and assures consumers with gluten sensitivities that a product meets the strict gluten-f...

Cheerios have been hit and miss for years, it has to do with how they get and sort the oats, the processing etc. Even the testing they do is iffy, there are reports STILL coming in about them making celiacs sick. We normally suggest avoiding oats for the first few months then if you want try rein...

I am from Canada and we were told at our Children's Hospital NOT to eat Cheerios. We were so excited that we had one box of cereal in our cupboard that has been a staple in my house for over 20 years that we were going to be able to keep. Then we were told that while they are considered gluten fr...

Did you ever get your celiac blood tests redone to see if the numbers are now in the normal range?