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Colon Neoplasia Co-existing with Celiac Disease in Older Patients: Coincidental, Probably; Important, Certainly
Celiac.com 08/27/2004 – The following abstract demonstrates the importance of follow up exams with your doctor, and also the importance of regular colon screenings for those with celiac disease.
BACKGROUND: Coeliac disease and colorectal neoplasia are both common, present most often in patients over 40 and cause similar symptoms. Greater awareness and early use of serological tests have improved the diagnosis of coeliac disease, but raise the concern that co-existing colorectal neoplasia may be missed. This study assessed the prevalence of colorectal neoplasia among patients with coeliac disease diagnosed after the age of 40 who presented with altered bowel habit or iron deficiency.
METHODS: All patients meeting the above criteria underwent colonoscopy unless this or barium enema had been performed shortly before.
RESULTS: Of 69 patients with coeliac disease undergoing colonoscopy, 7 (10%) had colon neoplasia: 5 had tubulovillous polyps, and 2 had carcinoma. The prevalence figures for coeliac patients undergoing colonoscopy with iron deficiency and altered bowel habit alone were 11% (5 of 47) and 10% (2 of 22), respectively None of a further 13 who had undergone previous colon investigation (all by barium enema) had neoplasia, although these were probably a selected population. The seven patients with colorectal neoplasia had not reported rectal bleeding. The prevalence of colorectal neoplasia was not significantly higher than in two series of non-coeliac patients undergoing colonoscopy for investigation of iron deficiency (12%) or altered bowel habit (8%).
CONCLUSIONS: There is a high prevalence of colorectal neoplasia among older patients with coeliac disease who present with iron deficiency or altered bowel habit, though this is no higher than for non-coeliac patients with these presentations. The possibility of dual pathology should be considered and excluded by colon investigation.
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Is Epitope-Specific Immunotherapy for Celiac Disease a Foundation for Future Autoimmune Vaccines?
Currently, immunosuppressant drugs are the only real treatment option for most autoimmune disorders, such as celiac disease and Type 1 diabetes.... [READ MORE]
Can Capsule Endoscopy Help to Diagnose Cases of Equivocal Celiac Disease in Adults?
There haven't been many studies that evaluate the usefulness of capsule endoscopy in equivocal celiac disease.... [READ MORE]
Do Reduced Polysaccharides in Gluten-free Diet Promote Bad Gut Bacteria?
Celiac,com 10/08/2010 - Many people are familiar with probiotics, such as acidophilus, Bifidobacterium bifidum, Bifidobacterium longum, Lactobacillus acidophilus, Lactobacillus case, which promote beneficial gut bacteria, and are commonly found in yogurt, kefir and other fermented milk products.... [READ MORE]
Gluten-Free Diet Recommended for Patients with Serum IgA Endomysial Antibodies but Normal Duodenal Villi Biopsy
The following abstract was submitted to celiac.... [READ MORE]
In 1994 I was diagnosed with celiac disease, which led me to create Celiac.com in 1995. I created this site for a single purpose: To help as many people as possible with celiac disease get diagnosed so they can begin to live happy, healthy gluten-free lives. Celiac.com was the first site on the Internet dedicated solely to celiac disease. In 1998 I foundedÂ The Gluten-Free Mall, Your Special Diet Superstore!, and I am the co-author of the book Cereal Killers, and founder and publisher of Journal of Gluten Sensitivity.View all articles by Scott Adams