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    Scott Adams
    Scott Adams

    Brain Perfusion Abnormalities Common in Untreated Celiac Disease

    Reviewed and edited by a celiac disease expert.

    Dig Liver Dis. 2004 Aug;36(8):513-8.

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    Celiac.com 12/11/2004 - An Italian study was carried out to determine the incidence of brain perfusion abnormalities in those with celiac disease, and whether gluten intake and associated autoimmune diseases may be considered risk factors in causing cerebral impairment. The researchers used brain single-photon emission computed tomography to examine the brains of 34 adult celiac patients--16 on a gluten-free diet, 18 on a gluten-containing diet, and 18 with other autoimmune diseases--and compared them to 10 age and sex-matched controls with normal jejunal mucosa. The researchers found that 24 out of the 34 in the study--a full 71%--had brain tomography abnormalities. The most significant brain abnormalities were found in the patients with untreated celiac disease (74%), and in those with associated autoimmune disease (69%). The abnormalities mainly affected the frontal region of the brain. The researchers conclude that brain perfusion seems common in celiac disease, but does not appear to be related to associated-autoimmunity, and the condition may be improved by a gluten-free diet.



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  • About Me

    Scott Adams

    Scott Adams was diagnosed with celiac disease in 1994, and, due to the nearly total lack of information available at that time, was forced to become an expert on the disease in order to recover. In 1995 he launched the site that later became Celiac.com to help as many people as possible with celiac disease get diagnosed so they can begin to live happy, healthy gluten-free lives.  He is co-author of the book Cereal Killers, and founder and publisher of the (formerly paper) newsletter Journal of Gluten Sensitivity. In 1998 he founded The Gluten-Free Mall which he sold in 2014. Celiac.com does not sell any products, and is 100% advertiser supported.


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