No popular authors found.
Ads by Google:

Categories

No categories found.


Get Celiac.com's E-Newsletter





Ads by Google:


Follow / Share


  FOLLOW US:
Twitter Facebook Google Plus Pinterest RSS Podcast Email  Get Email Alerts
SHARE:

Popular Articles

No popular articles found.
Celiac.com Sponsors:

Cancer: Small-Bowel Lymphoma Associated With Unrecognized Celiac Disease

Eur J Gastroenterol Hepatol 2000;12:645-648.

Ads by Google:

Celiac.com 08/13/2000 - According to Drs. Simon D. Johnston and R.G. Peter Watson from Royal Victoria Hospital in Belfast, Northern Ireland, UK, the incidence of undiagnosed celiac disease is higher among those with small bowel lymphoma, as reported in the June issue of the European Journal of Gastroenterology and Hepatology. According to the researchers: It is not clear whether the increased risk of small bowel lymphoma seen in typical celiac disease also applies to unrecognized or screening-detected celiac patients. To find an answer, they retrospectively identified 69 cases of small-bowel adenocarcinoma and 69 cases of small-bowel lymphoma from five pathology laboratories in Northern Ireland.

From a group composed of one patient with known celiac disease, and 12 with previously unrecognized celiac disease, the clinical presentation of adenocarcinoma and lymphoma patients was similar, but perforation was much more common among lymphoma patients. Further, 13 of the lymphoma patients, but none of the adenocarcinoma patients, had villous atrophy at a distant site, all of which were enteropathy-associated T-cell lymphomas. According to the researchers: Comparing the small-bowel lymphoma group to our random sample of the general Northern Ireland population as controls, the odds ratio of 15.72 for unrecognized celiac disease in the small-bowel lymphoma group, clearly indicates that there is an increased risk of unrecognized celiac disease among small-bowel lymphoma patients. Additionally, (s)ince a protective role for a strict gluten-free diet has been demonstrated, it follows that every effort should be made to diagnose celiac disease at every opportunity and raises the issue of whether population screening for celiac disease should be carried out.

Celiac.com welcomes your comments below (registration is NOT required).












Related Articles



Comments




Rate this article and leave a comment:
Rating: * Poor Excellent
Your Name *: Email (private) *:




In Celiac.com's Forum Now:


Hi Matt. Nice to meet someone from the U.K Thank you for your encouraging reply :). Yeah, I'm sure we all make mistakes at the start. I have however changed all my cutlery, plates, chopping boards and binned my toaster as I can't eat gluten-free bread due to the egg intolerance. I do th...

Wow, I was on the EXACT same stuff, it is basically medical speed, amphetamine. Yeah it will motivate you but it is addictive and withdrawal is a real nightmare with it. I use EXTRA b-vitamins and give myself a extra kick with a red eye coffee sometimes now days to avoid those pills. And I do not...

So I have one pesky symptom that in the last few years has cropped up and never gone away. Lack of motivation to do some very basic things. So basic it's embarrassing to talk about. I barely manage to do a lot of adult tasks these days. It's a real stretch. It's like something is blocking me. Any...

Yeah I need someone to attend with me, I had someone else but they canceled on me. The hotel room is booked from the 16th-20th of August. I can pick up from the airport, greyhound, or train station and drop off if need be, room is booked from the 16th technically a day before the convention so yo...

No anti-sm(lupus)? Yes, anti dsDNA is for SLE(lupus). No ENA panel,anti-RNP, anti-SS-A, anti-SS-B, anti histone, scl-70, etc? I'd ask for a referral, if you feel that there is something going on. I think that would be a logical step because of the positive ANA and lack of investigation. 1:640 is ...