Collagenous Sprue - The New England Journal of Medicine, December 10, 1970

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By Scott Adams

July 26, 1996
By Scott Adams • July 26, 1996

Collagenous Sprue - The New England Journal of Medicine, December 10, 1970

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Collagenous Sprue is a distinctive lesion of the intestinal mucosa associated with progressive malabsorption. The intestinal pathology is initially identified with the characteristic flat lesion of untreated Celiac Sprue. Thereafter, bands of eosinophilic hyaline material within the lamina propria become increasingly apparent. As the disease progresses, the mucosa becomes progressively thinner. Therapy, including the gluten-free diet, does not help. Some cases currently designated refractory or unclassified Sprue many prove to be Collagenous Sprue.
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Guest Mona Norton

Posted July 29, 2008

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Information is not explained enough. I understand this condition can be fatal if not diagnosed and treated

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Guest Babboo

Posted April 30, 2012

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It does a disservice to people newly diagnosed with collagenous sprue to print articles that are so old. As a patient who FORMERLY had c. sprue, I can testify that, with proper care by those practitioners (Dr. Green - my doctor - of Columbia Univ. NYC) who are most familiar with the disease, collagenous sprue can be cured. It is no longer the "death knell" that it used to be.

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Scott Adams was diagnosed with celiac disease in 1994, and, due to the nearly total lack of information available at that time, was forced to become an expert on the disease in order to recover. In 1995 he launched the site that later became Celiac.com to help as many people as possible with celiac disease get diagnosed so they can begin to live happy, healthy gluten-free lives. He is co-author of the book Cereal Killers, and founder and publisher of the (formerly paper) newsletter Journal of Gluten Sensitivity. In 1998 he founded The Gluten-Free Mall which he sold in 2014. Celiac.com does not sell any products, and is 100% advertiser supported.
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