No popular authors found.


Get Celiac.com's E-Newsletter

Categories

No categories found.







Ads by Google:


Questions? Join Our Forum:
~1 Million Posts
& Over 66,000 Members!



SHARE THIS PAGE:
Celiac.com Sponsors:

Liver Disease: Untreated Celiac Disease May Cause Liver Failure

Gastroenterology 2002;122:881-888.

Celiac.com 05/02/2002 - In the April issue of Gastroenterology Dr. Pekka Collin of the University of Tampere, Finland, and colleagues describe four patients with severe liver disease who were also found to have celiac disease. One of the patients had congenital liver fibrosis, one had massive hepatic steatosis, and two had progressive hepatitis without apparent origin. Three of the four were considered for liver transplantation. In each case a gluten-free diet reversed heptic dysfunction.

Ads by Google:

The reasearchers then studied the prevalence of celiac disease in 185 adults who had already undergone liver transplantation. Eight of them (4.3%) tested positive for celiac disease, and it had already been detected in six of the eight prior to transplantation. Only one the the diagnosed patients followed a strict gluten-free diet. Of these eight patients, three had primary biliary cirrhosis, one had autoimmune hepatitis, one had primary sclerosing cholangitis, and one had congenital liver fibrosis. Additionally, one of the patients had autoimmune hepatitis and one had secondary sclerosing cholangitis.

The researchers also noted that not all of patients with both liver and celiac disease showed symptoms of celiac disease, which suggests that the liver disease may not be caused by malabsorption. Dr. Collin suggests that it could be a "gluten-dependent immunologically induced extraintestinal manifestation of celiac disease."

The researchers conclude that some cases of serious liver disease may result from unrecognized celiac disease, and patients with severe liver disease should also be evaluated for celiac disease. Further, dietary treatment in patients with both celiac and liver diseases may prevent progression to hepatic failure, even in cases in which liver transplantation is considered.

Celiac.com welcomes your comments below (registration is NOT required).












Related Articles



1 Response:

 
Leslie Bragg
Rating: ratingfullratingfullratingfullratingfullratingfull Unrated
said this on
31 Jan 2008 12:07:37 PM PST
This is a very helpful article, but I would love more info re: celiac hepatitis, my diagnosis. The one with 'unknown origin' 'malabsorption.' I am strictly on the diet (4 months), but my doctors aren't doing anything else. I'm still very sick and would like to learn more.




Rate this article and leave a comment:
Rating: * Poor Excellent
Your Name *: Email (private) *:




In Celiac.com's Forum Now:


I have Julian Bakery Bars, Miracle Noodle MRE, I also have cans of freeze dried eggs. Gluten Free Emergency kits, Mountain House, Thrive, and Augason Farms (used to) have gluten free options of freeze dried foods. Make sure you check the box or look at the gluten-free versions of selections but t...

Almond flour is a VERY common one, look up recipes yourself, I have used coconut for a softer breading, works well, I have a customer at my bakery who claims she loves dipping her chicken in chia seeds then frying them...bit extra crunchy. I have used bean chips like Beanitos and Beanfields fla...

For chicken and fish I have always dipped them in regular all purpose flour or breadcrumbs but seeking a healthier option, any ideas please?

Thank you for all of the info/advice. From a Psoriatic standpoint I had to eat healthier no matter what so my diet changes will need to be focused on that. It's just a few simple foods I need to get clear on, maybe you can advise on this please? Is it ok for a Celiac to eat regular eggs or would ...

Beans and legumes do contain lectins. I am not sure if pressurized cooking really removes them (and I cook with one). I would look for scientific research and not a blog to back this up. If you suspect lectins are an issue for you and are willing to experiment, then completely remove them for...