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Liver Disease and Celiac Disease

This category contains summaries of research articles that deal with liver disease and it's association with celiac disease. Most of the articles are research summaries that include the original source of the summary.

    Photo: CC--K-State Research and Extension

    What's the relationship between celiac disease and liver histology, serology and treatment response?

    Celiac disease is diagnosed on the basis of ESPGHAN criteria, and clinical response to gluten-free diet. Researchers have noted histological abnormalities on liver biopsies in patients with celiac disease, but have rarely described the abnormalities in detail.

    A team of researchers recently set out to assess the histological spectrum of 'celiac hepatitis' and to see if a gluten-free diet can reduce such features. 

    Photo: CC--Michael Carian

    Some celiac patients suffer from liver damage that resolves after gluten-free diet; a condition known as "celiac hepatitis." A new study shows a connection to high antibody levels.

    San Diego's Normal Heights business district. Photo: CC--Tobin

    About four out of every ten celiac disease patients have abnormal liver function tests (LFTs) when first diagnosed, but a new study suggests that these abnormal tests usually return to normal once patients adopt a gluten-free diet.

    Slide showing non-alcoholic fatty liver disease. Photo: Wikimedia Commons--Nephron

    Non-alcoholic fatty liver disease is a common cause of chronic liver disease. There's good data showing that celiac disease changes intestinal permeability, and that treatment with a gluten-free diet often causes weight gain, but so far there is scant documentation of non-alcoholic fatty liver disease in patients with celiac disease.

    Photo: CC--Lecercle

    Researchers don't really have too much data on celiac disease in patients with cryptogenic cirrhosis or idiopathic noncirrhotic intrahepatic portal hypertension (NCIPH).

    Photo: CC--Bilal Kamoon

    A team of researchers recently set out to determine what factors contribute to hypertransaminasemia in patients with celiac disease.

    Photo: WikiMedia Commons

    Many people with celiac disease show slightly elevated liver enzymes, though these enzyme levels usually return to normal after gluten-free diet. A team of researchers recently set out to investigate the cause and prevalence of altered liver function tests in celiac patients

    New study on high transaminase levels in celiac disease.
    Some people who follow a gluten-free diet due to celiac disease may develop unusually elevated levels of liver enzymes, according to researchers from Finland. The results are reported online in the American Journal of Gastroenterology.

    New study indicates gut disease may play a role in non-cirrhotic intrahepatic portal hypertension.
    A research team concludes that gut-derived prothrombotic factors may contribute to the pathogenesis and prognosis of Non-cirrhotic Intrahepatic Portal Hypertension (NCIPH).

    A research team examined gut diseases and prognostic factors tied to non-cirrhotic intrahepatic portal hypertension.
    A research team set out to examine gut diseases and prognostic factors tied to non-cirrhotic intrahepatic portal hypertension.

    A new study provides demonstrates that small intestinal bacterial overgrowth and increased intestinal permeability are both associated with non-alcoholic fatty liver disease (NAFLD).

    A report in the February 3rd issue of Digestive and Liver Disease highlights the present understanding of transglutaminase function in gastrointestinal and liver diseases and therapeutic strategies that target transglutaminase activities.

    A team of researchers recently set out to examine the connection between celiac disease and primary biliary cirrhosis, primary sclerosing cholangitis and autoimmune hepatitis.

    About one person or so in every hundred has celiac disease, which means they suffer from a variety of associated symptoms along with intestinal damage and associated conditions. Research shows a connection between celiac disease and a variety of hepatic disorders. People with celiac disease have a higher instance of certain disorders of the liver. 05/31/2006 - I previously discussed how liver abnormalities are highly prevalent in celiac 04/27/2006 - Liver abnormalities have been found in a high percentage of celiacs when

    Aliment Pharmacol Ther. 2005; 21 (5): 515-518. 06/08/2005 – Australian researcher

    Gastroenterology 2002;122:881-888. 05/02/2002 - In the April issue of Gastroente

    Author: Hagander B; Berg NO; Brandt L; Nord en A; Sj olund K; Stenstam M. Source: Lancet, 19

    Author: Bardella MT; Fraquelli M; Quatrini M; Molteni N; Bianchi P; Conte D Address: Cattedra