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Depression and Celiac Disease

This category contains summaries of research articles that deal with depression and it's association with celiac disease. Most of the articles are research summaries that include the original source of the summary.

    Photo: CC--Guian Bolisay

    It’s no secret that psychological symptoms can be associated with celiac disease, but until recently, no one had really done a solid prospective study on children. A research team has now done just that. In this case, they looked at a group of children with celiac disease autoimmunity, which is persistently positive celiac disease–associated tissue transglutaminase autoantibodies (tTGA).

    Teens with celiac disease often have symptoms of depression. Image: CC--Rui Barros

    Recent studies indicate that depression and anxiety are the main reasons people with celiac disease report decreased quality of life.

    Image: CC--noshi

    Celiac disease has been linked to decreased quality of life and certain mood disorders. The effect of the gluten free diet on these psychological aspects of celiac disease is still unclear.

    Photo: CC-Edmund German
    Women with celiac disease face a higher risk for depression than the general population, even once they have adopted a gluten-free diet, according to U.S. researchers.

    Photo: CC - Jessia Hime
    A number of studies show that people with celiac disease have higher risk of depression and death from external causes, but there are no conclusive studies on death from suicide. A research team set out to more deeply examine the risk of suicide in people with celiac disease.

    Anxiety and Depression in Adults with Celiac Disease on a Gluten-free Diet
    A German study is the first to show that adult women who follow a gluten-free diet for celiac disease show higher levels of anxiety than do members of the general population.

    Patients with depression are told they have a chemical imbalance.  If someone else in their family is also depressed, the “gene card” is played.  “Your depression is genetic”, they are told. I have been in practice for over 20 years and I find the above data to be false.  Consistently we find patients who are suffering from depression and anxiety to be gluten sensitive.

    For the first time, medical researchers have shown that an activation of the inflammatory response system accompanies major depression and that pro-inflammatory cytokines and lipopolysaccharide (LPS) may trigger symptoms of depression.

    BMC Psychiatry 2005, 5:14 05/09/2005 – Past studies have linked depression and b

    Psychosomatics 45:325-335, August 2004 07/30/2004 - Past studies have reported a higher

    The Journal of Psychosomatic Research Volume 55, Issue 6, Pages 573-574 (December 2003)

    Addolorato G; Stefanini GF; Capristo E; Caputo F; Gasbarrini A; Gasbarrini G Institute of Intern 11/24/2002 - The following is a Medline abstract on a study conducted by Italian researc

    Source: Scandinavian Journal of Gastroenterology, 18:(2):299-304, 1983 Mar. Authors - Hallert