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Dyspepsia, Acid Reflux and Celiac Disease

This category contains summaries of research articles that deal with dyspepsia and acid reflux and their association with celiac disease. Most of the articles are research summaries that include the original source of the summary.


    What is eosinophilic esophagitis (EoE)? Let's break it down: The esophagus is the long tube that connects your mouth to your stomach. What goes through your esophagus? Food and drink. Eosinophils are a type of white blood cell that increases in the case of allergy.



    Photo: CC--Jacinta Illuch Valero

    People with celiac disease very often have reflux symptoms. A team of researchers recently set out to evaluate mucosal integrity and motility of the lower esophagus as possible contributors to reflux symptoms in patients with celiac disease.



    Photo: CC--Mike Licht

    Some studies have indicated higher rates of reflux in patients with celiac disease, but there hasn't really been any clear data on the risk for celiac disease in patients presenting with reflux.



    Photo: CC--Elvert Barnes

    What’s the relationship, if any, between eosinophilic esophagitis (EoE) and celiac disease? Research studies have produced variable results.



    Photo: CC Roadsidepictures

    Celiac disease has been linked to gastroesophageal reflux disease (GORD) and eosinophilic esophagitis (EoE). Researchers looked at rates of celiac disease in people with gastroesophageal reflux disease (GORD) and eosinophilic esophagitis (EoE).



    Photo: CC - GreenFlames09
    Many researchers suspect a connection between eosinophilic esophagitis and celiac disease in children. A research team sought to confirm this association in children, and determine whether it extends into adulthood.


    Photo: CC - JudeanPeoplesFront
    Gastroesophageal reflux symptoms are more severe in people upon diagnosis with celiac disease than in healthy controls, but are alleviated by assumption of a gluten free diet.

    A team of researchers recently set out to assess the recurrence of gastroesophageal reflux disease-related symptoms (GERD-rs), in celiac patients with nonerosive reflux disease (NERD).

    Bardella MT, Minoli G, Ravizza D, et al Arch Intern Med. 2000 May 22;160(10):1489-91 (Celiac.