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  • Refractory Celiac Disease & Collagenous Sprue

    Learn about refractory celiac disease and collagenous sprue, including persistent symptoms, villous damage, malabsorption, diagnosis, treatment options, follow-up testing, and complications that may occur when celiac disease does not respond as expected to a strict gluten-free diet. This section of Celiac.com helps people with celiac disease, gluten sensitivity, family members, and caregivers better understand serious or difficult-to-treat gluten-related conditions and why expert medical evaluation and ongoing care are important.

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