Jump to content
This site uses cookies. Continued use is acceptance of our Terms of Use and Privacy Policy. More Info... ×
  • Welcome to Celiac.com!

    You have found your celiac tribe! Join us and ask questions in our forum, share your story, and connect with others.




  • Celiac.com Sponsor (A1):



    Celiac.com Sponsor (A1-M):


  • Get Celiac.com Updates:
    Support Our Content
    eNewsletter
    Donate
  • Record is Archived

    This article is now archived and is closed to further replies.

    Jefferson Adams
    Jefferson Adams

    Dental Enamel Defects Indicate Adult Celiac Disease

    Reviewed and edited by a celiac disease expert.

    Celiac.com 08/23/2013 - Previous studies have noted the presence of dental enamel defects in people with celiac disease.

    Photo: CC--mmmcraftsA team of researchers recently set out to study the prevalence of dental enamel defects in adults with celiac disease, and to determine if there is in fact a connection between the grade of teeth lesion and clinical parameters present at the time of diagnosis of celiac disease.

    Celiac.com Sponsor (A12):
    The research team included L.Trotta, F. Biagi, P.I. Bianchi, A. Marchese, C. Vattiato, D. Balduzzi, V. Collesano, and G.R. Corazza.

    They are affiliated with the Coeliac Centre/First Department of Internal Medicine at the Fondazione IRCCS Policlinico San Matteo at the University of Pavia in Italy.

    The team looked at 54 celiac disease patients who had undergone dental examination. The patients included 41 females and 13 males, with an average age of 37±13 years, and with an average age of 31±14years at the time of diagnosis.

    Symptoms leading to diagnosis were diarrhea/weight loss (32 pts.), anaemia (19 pts.), familiarity (3 pts.). None of the patients was diagnosed because of enamel defects.

    At the time of evaluation, all of the patients were following a gluten-free diet.

    The team classified enamel defects from grade 0 to 4 according to severity. They found dental enamel defects in 46 of the 54 patients (85.2%). They found grade 1 defects in 18 patients (33.3%), grade 2 defects in 16 patients (29.6%), grade 3 defects in 8 patients (14.8%), and grade 4 defects in 4 patients (7.4%).

    They also observed that grades 3 and 4 were more common in patients diagnosed with classical rather than non-classical coeliac disease (10/32 vs. 2/20). However, this was not statistically significant.

    From this study, the team concludes that enamel defects are common in adult celiac disease, and that the observation of enamel defects offers a way to diagnose celiac disease.

    Source:

    •  Open Original Shared Link


    User Feedback

    Recommended Comments

    Guest Allison Adams

    Posted

    Can you describe what the dental defects were? How they were classified?

    Link to comment
    Share on other sites
    Guest Donnie

    Posted

    I had so many tooth enamel defects, and so did several other family members. Along with many classic celiac disease symptoms. But, only two of us were ever tested for celiac disease. And we were both adults at the time of our diagnosis. Autoimmune diseases run in my family on both sides. Especially thyroid disease.

    Link to comment
    Share on other sites
    Guest Lois Dean

    Posted

    It would be helpful to know the rate of dental enamel defects in a similar random group having no gluten sensitivity or celiac disease diagnosis.

    Link to comment
    Share on other sites
    Guest mary-anne

    Posted

    I was born with celiac disease, spent 18 months in the hospital on and off before it was diagnosed, went dormant when I was around 12 and returned at 45 (I'm now 51). I have ridges about 1/8" down/up from where tops and bottoms meet, my mom told me I was born with the ridges as a result of the disease... meaning I had celiac disease even in the womb, from what her understanding was through my 'specialist.' I was finally diagnosed at around 3 years old in Toronto Sick Children's hospital.

    Link to comment
    Share on other sites
    Guest Lynne
    I was born with celiac disease, spent 18 months in the hospital on and off before it was diagnosed, went dormant when I was around 12 and returned at 45 (I'm now 51). I have ridges about 1/8" down/up from where tops and bottoms meet, my mom told me I was born with the ridges as a result of the disease... meaning I had celiac disease even in the womb, from what her understanding was through my 'specialist.' I was finally diagnosed at around 3 years old in Toronto Sick Children's hospital.

    My sister and I both have dental defects. Four of my upper teeth and four of my lower teeth have discolored ridges. Dentists always said it must have been a high fever or tetracycline, but my mother said this was not the case. Those things didn't apply to us. My son was diagnosed with celiac disease last year at age 22. I am asymptomatic, but have been tested. Genetically, I have the highest possible risk factor in terms of my DNA, my blood serum showed elevated antibodies, but my endoscopy biopsy was only Marsh 1. My gastroenterologist said I did not have celiac disease and that I do not need to be gluten-free. I'm not sure what to believe. My mother, sisters and I have had autoimmune diseases, three of us with thyroid disorders.

    Link to comment
    Share on other sites


    Guest
    This is now closed for further comments

  • Get Celiac.com Updates:
    Support Celiac.com:
    Donate
  • About Me

    Jefferson Adams

    Jefferson Adams is Celiac.com's senior writer and Digital Content Director. He earned his B.A. and M.F.A. at Arizona State University. His articles, essays, poems, stories and book reviews have appeared in numerous magazines, journals, and websites, including North American Project, Antioch Review, Caliban, Mississippi Review, Slate, and more. He is the author of more than 2,500 articles on celiac disease. His university coursework includes studies in science, scientific methodology, biology, anatomy, physiology, medicine, logic, and advanced research. He previously devised health and medical content for Colgate, Dove, Pfizer, Sharecare, Walgreens, and more. Jefferson has spoken about celiac disease to the media, including an appearance on the KQED radio show Forum, and is the editor of numerous books, including "Cereal Killers" by Scott Adams and Ron Hoggan, Ed.D.

    >VIEW ALL ARTICLES BY JEFFERSON ADAMS

     


  • Celiac.com Sponsor (A17):
    Celiac.com Sponsor (A17):





    Celiac.com Sponsors (A17-M):




  • Related Articles

    Scott Adams
    Eur J Gastroenterol Hepatol. 2002 Apr;14(4):425-7. Related Articles, Links
    Celiac.com 07/30/2004 - The following abstract of a study that was done in 2002 emphasizes the importance of vitamin supplementation in the treatment of many celiacs:


    Dickey W. - Department of Gastroenterology, Altnagelvin Hospital, Londonderry BT47 6SB, Northern Ireland.
    OBJECTIVE: Although coeliac disease is a disorder of the proximal small bowel, associated vitamin B12 deficiency has been reported. This study aimed to assess the prevalence of B12 deficiency in a large series of coeliac patients, and to exclude the possibility that it is due to associated autoimmune gastritis.
    DESIGN: Prospective routine measurement of serum B12 in coeliac patients, with investigations for...


    Jefferson Adams
    Celiac.com 04/08/2009 - A study published in Journal of Insurance Medicine has delineated clear economic benefits to diagnosing celiac disease on a national level using a managed-care approach.
    A team of researchers based at Columbia University Medical Center's Celiac Disease Center  recently set out to estimate the rate of celiac disease diagnosis and assess the economic benefits of diagnosis by reviewing retrospective cohort studies from a national managed-care-population database. The research team was made up of Peter H. R. Green, Alfred I. Neugut, Afzal J. Naiyer, Z. Collette Edwards, Susan Gabinelle, and Vijit Chinburapa.
    Using the data, the team isolated cases of newly diagnosed with celiac disease. They also isolated 3 control groups that included people without a diagnosis ...


    Jefferson Adams
    Celiac.com 03/28/2012 - A clinical research team wanted to determine if adding ascorbate (vitamin C) to gliadin-stimulated biopsy culture could reduce the mucosal immune response to gliadin in people with celiac disease.
    The research team included D. Bernardo, B. Martínez-Abad, S. Vallejo-Diez, E. Montalvillo, V. Benito, B. Anta, L. Fernández-Salazar, A. Blanco-Quirós, J. A. Garrote, and E. Arranz. They are affiliated with the Mucosal Immunology Lab of the Department of Paediatrics & Immunology at Spain's Universidad de Valladolid-CSIC.
    Their quest was fueled by the understanding that the IL-15/NF-κB axis plays a key role in celiac disease. Because ascorbate is known to inhibit effects on NF-κB, the IL-15/NFκB axis looks like a good possible molecular target for reducing gliadin-...


    Jefferson Adams
    Researchers Use RNA-amplicon Sequencing to Spot Differences in Celiac Disease Epitopes in Durum Wheat Varieties
    Celiac.com 02/04/2014 - According to a new article by a team of researchers, not all gluten protein is created equal. That is, not all gluten proteins trigger an immune response in people with celiac disease.
    The research team included Elma M.J. Salentijn, Danny G. Esselink, Svetlana V. Goryunova, Ingrid M. van der Meer, Luud J.W.J. Gilissen, and Marinus J.M. Smulders. They are variously affiliated with the Plant Research International in Wageningen, The Netherlands, and the Vavilov Institute of General Genetics at the Russian Academy of Sciences in Moscow, Russia.
    Gluten proteins are the source of peptides that can trigger a T cell reaction in celiac disease patients, leading to inflammatory responses in the small intestine. Various peptides with three major T cell epitopes...


  • Recent Activity

    1. - PixieSticks replied to PixieSticks's topic in Super Sensitive People
      2

      Working in a kitchen with gluten?

    2. - BoiseNic replied to BoiseNic's topic in Dermatitis Herpetiformis
      11

      Skinesa

    3. - knitty kitty replied to Whyz's topic in Celiac Disease Pre-Diagnosis, Testing & Symptoms
      6

      Feeling ill

    4. - Scott Adams replied to Brianne03's topic in Celiac Disease Pre-Diagnosis, Testing & Symptoms
      5

      Advantages vs. Disadvantages of having an official Celiac diagnosis

    5. - Scott Adams replied to Whyz's topic in Celiac Disease Pre-Diagnosis, Testing & Symptoms
      6

      Feeling ill


  • Celiac.com Sponsor (A19):



  • Member Statistics

    • Total Members
      126,534
    • Most Online (within 30 mins)
      7,748

    Loneal67
    Newest Member
    Loneal67
    Joined

  • Celiac.com Sponsor (A20):


  • Forum Statistics

    • Total Topics
      120.9k
    • Total Posts
      69.5k

  • Celiac.com Sponsor (A22):





  • Celiac.com Sponsor (A21):



  • Popular Now

    • Whyz
      6
    • Art Maltman
      6
    • JA917
      13
    • Dana Gilcrease
      5
    • GardeningForHealth
  • Popular Articles

    • Scott Adams
    • Scott Adams
    • Scott Adams
    • Scott Adams
    • Scott Adams
  • Upcoming Events

×
×
  • Create New...