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    Nearly Two out of Three GI Endoscopes Contaminated with Retained Biopsy Samples

    Reviewed and edited by a celiac disease expert.

    Nearly two out of three endoscopes used to perform biopsies are contaminated with retained tissue, according to a new study.

    Nearly Two out of Three GI Endoscopes Contaminated with Retained Biopsy Samples - Image: CC BY 2.0--RinzeWind
    Caption: Image: CC BY 2.0--RinzeWind

    Celiac.com 08/24/2021 - We've written about high rates of tissue contamination in reprocessed duodenoscopes, and the FDA has warned about the deadly potential for infection in such cases, and encouraged the transition to disposable duodenoscopes.

    We also know about similar problems with endoscopes, but the latest news shows that the problem with contaminated biopsy endoscopes is much more severe than previously understood. 

    Celiac.com Sponsor (A12):
    The most recent study shows that nearly two in three endoscopes used for colonoscopy and esophagogastroduodenoscopy (EGD) procedures show a "startlingly high" rate of contamination from retained biopsy samples in the endoscope accessory channel or cap. This is a huge problem with potentially serious consequences for patients undergoing biopsy, as contaminated endoscopes can cause infection in many cases.

    In the study, conducted by Gregory Toy, MD, and colleagues at University of Utah Health, in Salt Lake City. investigators found 64% of 105 total endoscopies featured retained matter from biopsy samples, including more than three out of four EGDs and 50% of colonoscopies.

    When University of Utah Health polled its own endoscopists, they estimated the rate of contaminated scopes to be 10% to 15% of all scopes, far below the actual number of 64%, Gregory Toy, MD, told reporters. "The take-home message would be that retained biopsies are much more common than most endoscopists would think," adds Dr. Toy.

    Also worrying in the data was the high rate of retained biopsies found in EGDs compared to colonoscopies, said Dr. Toy. Increasing awareness about the high rate of retained biopsy samples in endoscopes, Dr. Toy suggests, may help clinicians to "change behavior to make this happen less often." Dr. Toy presented the findings during the Digestive Disease Week (DDW) 2021 virtual meeting.

    "Very Surprising" Results

    Calling the results "very surprising," session moderator Serge Sorser, MD, told reporters that "The study is very important as it points out a significant rate of tissue retention in the biopsy channel at the conclusion of endoscopic procedures."

    From the 2021 Digestive Disease Week (DDW) virtual meeting. [PAYWALL]


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    Distressed

    Five years ago the FDA mandated manufacturers to redesign scopes for this very reason. I refused to undergo EGD for this very reason, waiting patiently for invention of single-use scopes.  Now its time for the physicians & hospitals & OP clinics to make the necessary purchase.  Although the out-of-pocket expense will likely increase, it will be well worth the cost in order to prevent transfer of blood borne pathogens and neoplastic tissue.

    "FDA clears first fully disposable duodenoscope, eliminating the potential for infections caused by ineffective reprocessing | FDA"

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    Guest Bob
    3 hours ago, Distressed said:

    Five years ago the FDA mandated manufacturers to redesign scopes for this very reason. I refused to undergo EGD for this very reason, waiting patiently for invention of single-use scopes.  Now its time for the physicians & hospitals & OP clinics to make the necessary purchase.  Although the out-of-pocket expense will likely increase, it will be well worth the cost in order to prevent transfer of blood borne pathogens and neoplastic tissue.

    "FDA clears first fully disposable duodenoscope, eliminating the potential for infections caused by ineffective reprocessing | FDA"

    I have scheduled both an endoscopy and colonoscopy for the end of the year.  I will be inquiring if they use disposable instruments.  If they don't, I don't see how delaying or canceling the procedure is of much help.  You need to weigh the risks.  You're kind of stuck.  The procedure was a success, biopsies were benign but the resulting infection killed the patient.  

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    trents

    It also makes me wonder if when a biopsy sample is sent to a lab for analysis of potential celiac disease, whos tissue is being evaluated? Yours or the person who was scoped before you?

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    Distressed
    1 hour ago, trents said:

    It also makes me wonder if when a biopsy sample is sent to a lab for analysis of potential celiac disease, whos tissue is being evaluated? Yours or the person who was scoped before you?

    That depends.  When a tissue is biopsied it is held by a "pincer" and withdrawn from the scope.  If there is a "washing" then the fluid is aspirated along with any material (fluid or solid material) into a suction trap.  That collection could lead to false diagnostic results. 

    HIV, Hepatitis B&C and MRSA are dangerous blood borne pathogens. Cancer cells transferred to a healthy patient are typically not a risk, but celiac disease patients have "immunological" disorders (often multiple problems). 

    The disposable scope was approved in 2019, but I have yet to hear of its wide-range use. Facilities are often "resistant" to spending money on these items. I remember one hospital chain used "disposable" intubation scopes.  That was a "safe" move, but no one else perceived of the "risk management".  As it regards EGD/colonoscopy scopes: in 1994 a new washer was patented.  That machine thoroughly cleaned scopes.  Again dollar investment is the issue.  Typically, it is the radiology department that makes the most revenue and is the division that receives most of the upgraded equipment.

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    Scott Adams was diagnosed with celiac disease in 1994, and, due to the nearly total lack of information available at that time, was forced to become an expert on the disease in order to recover. In 1995 he launched the site that later became Celiac.com to help as many people as possible with celiac disease get diagnosed so they can begin to live happy, healthy gluten-free lives.  He is co-author of the book Cereal Killers, and founder and publisher of the (formerly paper) newsletter Journal of Gluten Sensitivity. In 1998 he founded The Gluten-Free Mall which he sold in 2014. Celiac.com does not sell any products, and is 100% advertiser supported.


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