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mjr6

Duodenitis After 16 Years On The Diet

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I have two family members that have been on the gluten-free diet for 15 & 16 years and they have followed the diet strictly (barring a few restaurant mishaps) and yet both of them still suffer intense intestinal pain and duodenal biopsies still show a lot of inflammation of the duodenum.

Could this be refractory celiac disease? I didn't think so because in many other ways they have responded well to the diet, their villi is much improved. But it seems the definition of RCD are changing. Are steroids and thiopurines useful in dealing with this intestinal inflammation?

I would appreciate any info or advice. Thnx

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