Jump to content
This site uses cookies. Continued use is acceptance of our Terms of Use and Privacy Policy. More Info... ×
  • Welcome to Celiac.com!

    You have found your celiac tribe! Join us and ask questions in our forum, share your story, and connect with others.




  • Celiac.com Sponsor (A1):



    Celiac.com Sponsor (A1-M):


  • Get Celiac.com Updates:
    Where Your Contribution Counts!
    eNewsletter
    Support Us!

Can Someone Please Help With My Blood Results


niese

Recommended Posts

niese Explorer

Here are my blood results, my GI dr said I am boarderline Celiac, ok whatever doc.  I have found a new GI dr that is suppose to be a specialist in Celiac but I don't see him till Aug 20th.

 

 

IgA Serum        248

Reference range 81 to 463

 

Gliadin Antbody, IgG    23

Reference range <20

 

Gliadin Antibody, IgA  6

Reference range <20

 

tTG IgA Antibody   1

Reference range <4

 

The biopsy suggest I have Celiac as well.

 

can anyone please tell me what my blood work means?

 

I was still eating gluten at the time of my test but I am now gluten free for almost 2 months.  

 

Thanks

 

 

Link to comment
Share on other sites

Celiac.com Sponsor (A8):
Celiac.com Sponsor (A8):



Celiac.com Sponsor (A8-M):



nvsmom Community Regular

The total serum IgA is the control test to make sure you make enough immunoglobulin A for the othet tests to be accurate (5% of celiacs don't). Yours is in the middle of normal and perfect.

 

The Gliadin antibody tests are most likely the anti-gliadin antibodies (AGA Iga and AGA IgG) tests. That's an older test and not usesd as often anymore partially due to it's unreliability. That test indicates gliadin sensitivity. It is the only test that does not test for damage being done to the intestinal villi, and for those reasons it is thought by some to test for celiac disease and for NCGS (non-celiac gluten sensitivity).  A positive AGA IgG indicates celiac disease or even possibly NCGS.

 

It's a shame that they did not test your tTG IgG, you could be one of those people whose serological tests tend to be positive in the immunoglobulin G's instead of IgA's. The IgA and IgG's are just parts of the immune response that are made in different parts of the body. IgA is used more proabably because it is made in the mucosal areas of the body like the gut, whereas the IgG is more ssytemic (as I understand it). You might want to ask for the tTG IgG test.

 

They did not run the DGP (deaminated gliadin peptide) tests which are the newest tests around. These tests seem to catch a lot of the early cases like in young kids. You might want to request them too. They did not run the EMA IgA, but if your tTG IgA was negative, chances are that it would be too.

 

To me, your blood work says celiac disease, or possibly NCGS but because your biopsy suggests celiac disease, then that positive AGA must be from celiac disease. You are in the gluten-free for life club.  ;)

Link to comment
Share on other sites
niese Explorer

The total serum IgA is the control test to make sure you make enough immunoglobulin A for the othet tests to be accurate (5% of celiacs don't). Yours is in the middle of normal and perfect.

 

The Gliadin antibody tests are most likely the anti-gliadin antibodies (AGA Iga and AGA IgG) tests. That's an older test and not usesd as often anymore partially due to it's unreliability. That test indicates gliadin sensitivity. It is the only test that does not test for damage being done to the intestinal villi, and for those reasons it is thought by some to test for celiac disease and for NCGS (non-celiac gluten sensitivity).  A positive AGA IgG indicates celiac disease or even possibly NCGS.

 

It's a shame that they did not test your tTG IgG, you could be one of those people whose serological tests tend to be positive in the immunoglobulin G's instead of IgA's. The IgA and IgG's are just parts of the immune response that are made in different parts of the body. IgA is used more proabably because it is made in the mucosal areas of the body like the gut, whereas the IgG is more ssytemic (as I understand it). You might want to ask for the tTG IgG test.

 

They did not run the DGP (deaminated gliadin peptide) tests which are the newest tests around. These tests seem to catch a lot of the early cases like in young kids. You might want to request them too. They did not run the EMA IgA, but if your tTG IgA was negative, chances are that it would be too.

 

To me, your blood work says celiac disease, or possibly NCGS but because your biopsy suggests celiac disease, then that positive AGA must be from celiac disease. You are in the gluten-free for life club.  ;)

Thanks Nicole, so when I request these other test you suggested do I have to go back to eating gluten for them? I pray not cause I feel about 75% better now that I have gone gluten-free.  If dr can just get my bowels under control life would be great. 

Link to comment
Share on other sites
GottaSki Mentor

Thanks Nicole, so when I request these other test you suggested do I have to go back to eating gluten for them? I pray not cause I feel about 75% better now that I have gone gluten-free.  If dr can just get my bowels under control life would be great. 

 

Welcome Niese!

 

I agree that both a tTG IgG and DGP IgG should have been run before gluten was removed.  I suggest you still have them done just so your chart has the full antibody panel as close to removing gluten as possible. 

 

Since your biopsy indicated Celiac Disease as well - I do not suggest returning to eating gluten for any tests now.  I do suggest you get a written or electronic copy of both the procedural and pathology reports of your endoscopy to find out exactly what type of damage was seen or revealed via biopsy.

 

I also suggest you call your primary's office and ask if they can order the missing tests from your Celiac Antibody Panel along with nutrient testing - as malabsorption of nutrients is another strong indicator of Celiac and this info is important if you need to be supplementing any nutrients while healing.  If your primary says no, try getting a message to the Celiac specialist that you are already gluten-free -- perhaps they can move the appt up or order the tests now so he/she will have the results for your appointment next month.

 

Below are the nutrient tests my Celiac Doc ran at diagnosis and annually - if you did not have these done during your diagnosis process - I would add them now so you have as close to starting data as possible.:

 

B1, B2, B6, B12, D, K, Iron, Ferritin, Copper and Zinc

CMP

CBC

 

Hang in there :)

Link to comment
Share on other sites
niese Explorer

Welcome Niese!

 

I agree that both a tTG IgG and DGP IgG should have been run before gluten was removed.  I suggest you still have them done just so your chart has the full antibody panel as close to removing gluten as possible. 

 

Since your biopsy indicated Celiac Disease as well - I do not suggest returning to eating gluten for any tests now.  I do suggest you get a written or electronic copy of both the procedural and pathology reports of your endoscopy to find out exactly what type of damage was seen or revealed via biopsy.

 

I also suggest you call your primary's office and ask if they can order the missing tests from your Celiac Antibody Panel along with nutrient testing - as malabsorption of nutrients is another strong indicator of Celiac and this info is important if you need to be supplementing any nutrients while healing.  If your primary says no, try getting a message to the Celiac specialist that you are already gluten-free -- perhaps they can move the appt up or order the tests now so he/she will have the results for your appointment next month.

 

Below are the nutrient tests my Celiac Doc ran at diagnosis and annually - if you did not have these done during your diagnosis process - I would add them now so you have as close to starting data as possible.:

 

B1, B2, B6, B12, D, K, Iron, Ferritin, Copper and Zinc

CMP

CBC

 

Hang in there :)

Thanks for the info I do have these test on my list to ask my dr for.  I will call my old GI dr tomorrow to request the test results of my biopsy, thanks for being so helpful. I DO NOT want to return to eating gluten I was way too sick and in too much pain it was so bad no pain meds helped me I just had to deal with the pain  :(

Link to comment
Share on other sites
GottaSki Mentor

Thanks for the info I do have these test on my list to ask my dr for.  I will call my old GI dr tomorrow to request the test results of my biopsy, thanks for being so helpful. I DO NOT want to return to eating gluten I was way too sick and in too much pain it was so bad no pain meds helped me I just had to deal with the pain  :(

 

Completely understand and agree....you seem to have enough for on official diagnosis -- but things can go a bit wonky with the process at times....the tests are not perfect and the system is far, far from perfect.

 

Your improvement gluten-free is another huge piece of the puzzle....happy to hear you have already had some :)

Link to comment
Share on other sites
niese Explorer

Completely understand and agree....you seem to have enough for on official diagnosis -- but things can go a bit wonky with the process at times....the tests are not perfect and the system is far, far from perfect.

 

Your improvement gluten-free is another huge piece of the puzzle....happy to hear you have already had some :)

Thank you

Link to comment
Share on other sites

Celiac.com Sponsor (A8):
Celiac.com Sponsor (A8):



Celiac.com Sponsor (A8-M):



nvsmom Community Regular

I think you might as well get tested too, even if you have been gluten-free for a few months as sometimes the antibodies stay elevated for quite some time gluten-free. my tTG IgA was still elevated after a year so I know it can happen.

I hope you continue to feel better gluten-free.

Link to comment
Share on other sites
niese Explorer

I think you might as well get tested too, even if you have been gluten-free for a few months as sometimes the antibodies stay elevated for quite some time gluten-free. my tTG IgA was still elevated after a year so I know it can happen.

I hope you continue to feel better gluten-free.

 

I think you might as well get tested too, even if you have been gluten-free for a few months as sometimes the antibodies stay elevated for quite some time gluten-free. my tTG IgA was still elevated after a year so I know it can happen.

I hope you continue to feel better gluten-free.

Thank you

Link to comment
Share on other sites

Archived

This topic is now archived and is closed to further replies.

  • Get Celiac.com Updates:
    Help Celiac.com:
    Donate

  • Celiac.com Sponsor (A17):
    Celiac.com Sponsor (A17):





    Celiac.com Sponsors (A17-M):




  • Recent Activity

    1. - Braver101 posted a topic in Coping with Celiac Disease
      0

      Constant sweating with celiac disease

    2. - Tlbaked13 replied to djmu's topic in Related Issues & Disorders
      10

      Peripheral Neuropathy

    3. - trents replied to djmu's topic in Related Issues & Disorders
      10

      Peripheral Neuropathy

    4. - Tlbaked13 replied to djmu's topic in Related Issues & Disorders
      10

      Peripheral Neuropathy


  • Celiac.com Sponsor (A19):



  • Member Statistics

    • Total Members
      120,485
    • Most Online (within 30 mins)
      7,748

    Julie Riordan
    Newest Member
    Julie Riordan
    Joined

  • Celiac.com Sponsor (A20):


  • Forum Statistics

    • Total Topics
      120.2k
    • Total Posts
      1m

  • Celiac.com Sponsor (A22):





  • Celiac.com Sponsor (A21):



  • Upcoming Events

  • Posts

    • Braver101
      Does anyone else get soaking wet sweats just out of nowhere? I’m not in menopause, there’s nothing wrong with me except celiac disease and my thyroid, and I’m taking my medicine. I am 18 days gluten-free but I cannot stop sweating and it makes me freezing cold and I’m soaking wet and changing my clothes literally as I’m changing my clothes the new clothes are soaking wet and nobody will help me. Please somebody out there help me. 
    • Tlbaked13
      Sometimes I end up spitting out a drink of water! But for the most part I do ok with the liquids that I've been sticking to which Is hardly anything carbonated (meaning diet soda mainly)  I drink alot of tea which I make myself lipton cold brew sweetened with half sugar and half Splenda, smoothies when I could in the beginning but made with milk so I'm now using orange juice instead of the milk but it doesn't workout real often I drink black coffee in the mornings with no trouble usually and I've been experimenting with some juices but the sugar content is a set back I'm not a huge water fan but will drink it unfortunately where I live I can't do the tap water I'm the only one who has a problem with it apparently but for some reason I just can't...unless I'm using it in coffee or tea and the tea even took me some time to stand yes I have thought about boost/ ensure but they are very costly for someone who is scrapping the bottom at this time 
    • trents
      Do you believe your swallowing is a manifestation of your neuropathy? I'm thinking if you are having trouble getting food down you need to focus on consuming things that have a high nutritional density so that whatever you are able to get down counts for something. Have you looked at Boost and other high protein/high calorie shake products?  They are fortified with vitamins and minerals as well. Do you have any trouble with aspiration of liquids? For celiac testing purposes, the guidelines are calling for daily consumption of about 10gm of gluten - the amount in about 4-6 slices of bread - in order to ensure valid testing. That sounds like it would be a challenger for you.
    • Tlbaked13
      Thank you and I am aware that I should be eating a "normal" diet until tested it's kind of been trial and error for my diet or more like just ERROR! I about 1-3 bites a meal I'm to a point that 99 percent of the time I'm having trouble swallowing just about everything occasionally I find either something or a very small window of time that allows me to get very little of something! I am basically getting zero nutrition what so ever because I take one bite of the meal that I usually just slaved over just to end up tossing it when it's all said and done...did anyone else ever experience anything like this?  I am more then open to suggestions! It is taking a very extreme toll on me and my body forsure 
    • JustGemi
×
×
  • Create New...