Celiac.com Sponsor (A1):



Celiac.com Sponsor (A1-m):


  • You've found your Celiac Tribe! Join our like-minded, private community and share your story, get encouragement and connect with others.

    💬

    • Sign In
    • Sign Up

Archived

This topic is now archived and is closed to further replies.

BelleVie

Well Whaddya Know, My Biopsy Was Positive After A 6 Week Challenge

Recommended Posts

Hi! I just wanted to let anyone know who is interested in the timing of gluten challenges that after being gluten free for 9 months, I did a 6 week gluten challenge and got the results of my biopsy this morning which showed slight villous atrophy and increased lymphocytes. My TtG test, however, was negative, which I expected. During the challenge, I ate a pretty obscene amount of gluten, usually having bread at every meal. And lots of donuts. Oh the donuts!  :P

 

I actually feel really good and very thankful that I finally know for sure that this is the reason for feeling so "off" for most of my life, and for all of the weird illnesses I've been through. Now I'm hoping that my family will take my requests for them to get tested seriously! 

 

Thank you to everyone for all of the help and advice you have offered in the short time that I've been a member of this forum. I hope to be able to pay it forward! 

Share this post


Link to post
Share on other sites

Celiac.com Sponsor (A8):

Celiac.com Sponsor (A8):


so glad that you got an answer!!  happy healing time :)


Diagnosed with celiac disease, but my fat malabsoption, EPI and Vitamin K deficiency have finally cleared themselves up do to the help from Creon!

Thankful for all the help I've received from members on this board!

Happy to have answers  :) 

Share this post


Link to post
Share on other sites

That's great that you got a clear diagnosis! Now you know for sure.

May I ask if your biopsy report said which part of the intestines had the villous atrophy? I was shocked that my biopsy came back negative after a six-week challenge, but they didn't do lymphocyte counts and did not take any samples from my duodenal bulb. Just wondering if the duodenal bulb is usually the first place to show damage.

I hope you're feeling better and that things just keep improving from here!


Daughter: Positive tTG-IgA, DGP-IgA, and DGP-IgG. Celiac confirmed by biopsy in June 2013, at age four. Clear gastrointestinal, behavioral, and neurological/sensory symptoms since very early infancy, even when exclusively breastfeeding.

Me: Diagnosed by GI with "presumed celiac" based on health history, celiac in family, and resolution of fat malabsorption and many other symptoms on gluten-free diet. Long history of eczema, chronic diarrhea, steatorrhea, ataxia, peripheral neuropathy, infertility, chronic insomnia, low cholesterol, vitamin deficiencies, and joint pain. Negative celiac tests after 15 years gluten-light and then a brief but awful gluten challenge. 

Share this post


Link to post
Share on other sites

Good to know you had a positive biopsy result after challenge...and happy for you that you can be sure of the transitioning to a completely gluten-free life.  Thanks for sharing :)


-Lisa

Undiagnosed Celiac Disease ~ 43 years

3/26/09 gluten-free - dignosed celiac - blood 3/3/09, biopsy 3/26/09, double DQ2 / single DQ8 positive

10/25/13 - MCAD

Health history since celiac diagnosis became too long -- moved to the "about me" section of my profile

My children and I all have multiple copies of the genes for Celiac Disease, along with large variety of symptoms/resolution gluten-free

Current tally from me, three kids and two grands: 4 diagnosed with Celiac Disease, 2 NCGS

Get PROPERLY tested BEFORE REMOVING GLUTEN.

ALWAYS independently research health related information found on internet forums/blogs.

"LTES" a Gem :)

Share this post


Link to post
Share on other sites

Thank you, everyone. I'm really looking forward to getting healthy for good!

 

Greenbeanie, my pathology report just says "Duodenum, site unstated, blunting of villi, increased intraepithelial lymphocytes in tip of villi/suggestive of celiac disease." I was under the impression that that duodenal bulb was the most likely place to find damage. Is it possible for you to get a second opinion? I think that the only reason my doctor knew to be on the lookout for the increased lymphocyte count in the villi tips was because I gave him a copy of the study that came out this year on that topic. If they still have your slides, maybe someone could go back in and have another look?

 

Oh one more thing that I forgot to mention is that he also did some kind of staining during the endoscopy, where he sprayed a blue dye which made it easier to see the patterning in my small intestine, and you could see in the photos areas that were patchy and didn't show up as clearly as others. I'd never heard of that before on any other site, so I just thought it was interesting to share. 

Share this post


Link to post
Share on other sites

I had never heard of it before, which is why I was so surprised when my doctor showed me the images. And I was just so impressed with my doctor! He spent an HOUR with me explaining everything he looked at and all of his results. He even got out a sketchpad and drew a few diagrams for me! 

Share this post


Link to post
Share on other sites

I had never heard of it before, which is why I was so surprised when my doctor showed me the images. And I was just so impressed with my doctor! He spent an HOUR with me explaining everything he looked at and all of his results. He even got out a sketchpad and drew a few diagrams for me! 

 

I love doctors like this (bless their souls!). Wish they were a dime a dozen?!? :P 


Canadian undergraduate student in 3rd year, studying Psychology and Speech Communication. Hoping to go into rehabilitation sciences!  B)

  

Dx with: 

Hashimoto's thyroiditis - 22/09/12

benign paroxysmal positional vertigo (bppv) - 18/05/13

irritable bowel syndrome - 21/06/13 

HLA-DQ8 gene ~ heterozygous (moderate risk for celiac) - 29/11/13

 

-> underwent a colonoscopy on 24/08/13, showed mild focal colitis + lymphoid hyperplasia (aka inflammation) in terminal ileum

Share this post


Link to post
Share on other sites