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Also, uhm.. No one's heard of IgG food intolerance testing? I know it's somewhat controversal, and that elimination diets are typically what people do to try to figrie stuff out but I've already eliminated SO much and it still seems I react to absolutely everything I eat.

 

I feel like I'm drowning.

I've been on this paleo diet for 5 months and I feel worse and worse everyday. I don't know how much more I can take of this.. My stomach is stretched out so far it literally hurts to breathe!! I don't care what it is I'll have to do as long as I can get better. No one's been able to help me. My old GI doctor went as far as saying that it's IBS and I'll probably just feel like this forever. Granted, she also originally doubted I had Celiac Disease (before I got the biopsy and bloodwork) soley because diarrhea wasn't one of my symptoms... -__-

I don't know how much more of this I can take. THis whole thing has taken over me entirely. I'm not myself at all anymore. I don't care about any of the things I used to care about. I rarely even leave me house. I'm in constant agony 24/7...sometimes I"ll spend entire days crying... I feel like I'm being punished in a way. I was never really a happy person and now I realize how much I should have appreciated my life while I still had one.

I'm afraid I'll have to live like this forever. After 5 months gluten free, dairy free, grain free, sugar free, taking a hundred supplements a day and I'm WORSE than I was before I was even diagnosed.....something's gotta be wrong. SOmething else.

Sorry for whining like this lol I know some of you don't really wanna hear it. I know my parents and my boyfriend are tired of hearing it. All I talk about it Celiac Disease and trying to find out what's wrong. I tried the FODMAP diet, the SCD diet, I once even did 2 weeks of eating nothing but homemade soup, gelatin, and baby food veggie purrees. Nothing helps at all. I never get a chance to breathe.

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my main symptom is constipation, not diarrhea.

 

You have this in common with me. I know a lot about dealing with constipation so let me know if I can help with that at all. If you are not going enough, that will cause you to feel terrible, trust me, and it can definitely cause the bloating. One thing I will mention is that it's important to get the right balance of fiber. Insoluble fiber speeds up digestion and soluble fiber slows it down. For the most part insoluble fiber is the outer layer of foods, like the skin on an apple, and soluble fiber is what's inside, like the white part of the apple. There are some exceptions. It's crucial to get enough insoluble fiber. Green Beans, peas, and artichokes are some good sources.

 

Food Intolerance testing is controversial and I don't know much about it but there are people who have used it on this site, and others who don't believe in it, if you want to post a separate topic about to get more responses.

 

You WON'T feel like this forever. GI's are generally disappointing. There's A Lot they don't know and they are not open to new concepts. A Naturopathic Doctor (ND) can be helpful thinking outside the box, and GI's won't help much with diet, strange as that is. GI's are pretty clueless about things outside of tests, prescriptions and surgery.Your GI sounds quite unhelpful and discouraging, I would seriously find a different one.

 

You're right though, there has to be something that is still off if you're feeling that bad. When you figure it out you will feel better. The way you're feeling now is not permanent, but it is something that needs attention right away. You need relief.

 

I'm really wondering about the constipation issue. If you are having trouble with that and want to discuss it more thoroughly you can PM me. I've learned a lot about it, and not going enough will make your life feel like hell. It can cause severe psychological symptoms as well as physical ones when it gets bad enough.

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I have done the IgG food intolerance testing and felt it was a real help to me. It tests the blood for antibodies to foods that you are eating.  You must be eating the foods to be a valid test.  I also have used a rotational diet to help find foods I don't tolerate.  You might try new meats and new vegetables, that you hadn't eaten over the years that you were ill.  These you shouldn't have antibodies too.

 

Please don't give up.  The process can be complicated, but it does get easier as one peels off layers of illness.  You are traveling up hill, but even when you don't see through the fog, when you are going up, you will get somewhere.

 

Feel free to Pm me if you want to discuss the tests further.  Natural practitioners often use them, and I use natural practitioners to help me in healing after 30+ years of trouble.

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Also, uhm.. No one's heard of IgG food intolerance testing? I know it's somewhat controversal, and that elimination diets are typically what people do to try to figrie stuff out but I've already eliminated SO much and it still seems I react to absolutely everything I eat.

 

I feel like I'm drowning.

I've been on this paleo diet for 5 months and I feel worse and worse everyday. I don't know how much more I can take of this.. My stomach is stretched out so far it literally hurts to breathe!! I don't care what it is I'll have to do as long as I can get better. No one's been able to help me. My old GI doctor went as far as saying that it's IBS and I'll probably just feel like this forever. Granted, she also originally doubted I had Celiac Disease (before I got the biopsy and bloodwork) soley because diarrhea wasn't one of my symptoms... -__-

I don't know how much more of this I can take. THis whole thing has taken over me entirely. I'm not myself at all anymore. I don't care about any of the things I used to care about. I rarely even leave me house. I'm in constant agony 24/7...sometimes I"ll spend entire days crying... I feel like I'm being punished in a way. I was never really a happy person and now I realize how much I should have appreciated my life while I still had one.

I'm afraid I'll have to live like this forever. After 5 months gluten free, dairy free, grain free, sugar free, taking a hundred supplements a day and I'm WORSE than I was before I was even diagnosed.....something's gotta be wrong. SOmething else.

Sorry for whining like this lol I know some of you don't really wanna hear it. I know my parents and my boyfriend are tired of hearing it. All I talk about it Celiac Disease and trying to find out what's wrong. I tried the FODMAP diet, the SCD diet, I once even did 2 weeks of eating nothing but homemade soup, gelatin, and baby food veggie purrees. Nothing helps at all. I never get a chance to breathe.

You are not alone.  You can PM me anytime as well.  It is exhausting and you want to scream, cry, give up, after talking to a GI you can even think am I nuts?  But, no, you know your body, and the test proves the food issues even if the GI tests are not showing all of them.  Being able to wear something one day and then not the next just because you ate something wrong.  Only someone that goes through it can understand it.  The C my hubby and I joked about it for years, until we realized how serious it was.  Last time in they weighed me, and I said really I gained 7 pounds in a week?  They will not do a colonoscopy, as I am not 50 yet??  Mostly what I eat these days are protein shakes and veggie juices.  I have a list of reflux friendly foods, low fodmap foods, of course gluten-free, and my food testing list, I match them up and see what I can have, and go from there.  I do not even like to go out anymore and I used to love to go out to dinner, we live around awesome restaurants.  Anyway, I get it.  You are not alone.... 

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AnnaChristine.

 

You said "After 5 months gluten free, dairy free, grain free, sugar free, taking a hundred supplements a day and I'm WORSE than I was before I was even diagnosed.....something's gotta be wrong. SOmething else. " 

 

Are you really taking a hundred supplements a day.  Um...That could be a problem.  Why?  Does your Doctor approve of all the suppliments?  Have you checked for Interactions of all the Suppliments?

 

Colleen

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AnnaChristine.

 

You said "After 5 months gluten free, dairy free, grain free, sugar free, taking a hundred supplements a day and I'm WORSE than I was before I was even diagnosed.....something's gotta be wrong. SOmething else. " 

 

Are you really taking a hundred supplements a day.  Um...That could be a problem.  Why?  Does your Doctor approve of all the suppliments?  Have you checked for Interactions of all the Suppliments?

 

Colleen

You can have your vitamin levels checked.

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AnnaChristine...I'm so sorry you are going through this.  I can feel your frustration.  As a mom of 3 I just want to give you a big ((((hug))).  I hope you are able to get some answers.  Know that you are not alone.

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AnnaChristine.

 

You said "After 5 months gluten free, dairy free, grain free, sugar free, taking a hundred supplements a day and I'm WORSE than I was before I was even diagnosed.....something's gotta be wrong. SOmething else. " 

 

Are you really taking a hundred supplements a day.  Um...That could be a problem.  Why?  Does your Doctor approve of all the suppliments?  Have you checked for Interactions of all the Suppliments?

 

Colleen

lol no obviously not a hundred :P But I do take a lot.

 I'm taking a supplement caleld DIgestive Advantage Constipation formula which helps me stay somewhat regular. I take a fish oil pill. A probiotic (acidophilus). Digestive enzymes with every meal. L-Glutamine on it's own, and also something called G.I. Revive powder which also contains L-Glutamine along with glucosamine, citris pectin, aloe vera, slippery elm, marshmallow, mucin, chamomille, okra extract, cat's claw, msm, prune powder, and zinc. I've heard many good things about the GI Revive which I just odered about a week ago, so I guess it's too soon to tell if it'll help. I also take regular vitamins (which yes are gluten-free....i know some of you are going to ask that)

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Hi AC18,

 

The last time I got glutened good it took about 6 weeks for the symptoms to fade,  So you are getting close to that time since you were glutened.  Just a thot.

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lol no obviously not a hundred :P But I do take a lot.

 I'm taking a supplement caleld DIgestive Advantage Constipation formula which helps me stay somewhat regular. I take a fish oil pill. A probiotic (acidophilus). Digestive enzymes with every meal. L-Glutamine on it's own, and also something called G.I. Revive powder which also contains L-Glutamine along with glucosamine, citris pectin, aloe vera, slippery elm, marshmallow, mucin, chamomille, okra extract, cat's claw, msm, prune powder, and zinc. I've heard many good things about the GI Revive which I just odered about a week ago, so I guess it's too soon to tell if it'll help. I also take regular vitamins (which yes are gluten-free....i know some of you are going to ask that)

 

What are some of those supplements for?  They are not typical for a recovering Celiac or the Nutritionally deprived. Do they have any interactions with each other?

 

Colleen

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Maybe try going off paleontologists?  I felt awesome on it at first, but then I started eating more nuts, and oh my goodness, the bloating, pain, and diarrhea were awful, I tried almond milk a few weeks ago, it went right through me (sorry if that grosses anyone out).  But that was much better than actual nuts, because the pain lasts for days.

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It's important to have someone monitoring all the supplements you are taking. It's true, they could be interacting with one another in bad way, and the one with the long list of ingredients could be bothering you. Sometimes for us the natural ingredients may sound good but can be related to something that is a problem for celiacs.

 

You need to have your vitamin and mineral levels checked by a lab that is ordered by some kind of professional healthcare provider, Find a Naturopathic Dr. preferably, or a nutritionist, or someone qualified who takes a more natural holistic approach - not a GI.

 

This isn't something you can do all by yourself. Vitamin/mineral deficiencies or taking too much of the wrong thing can have serious consequences to your health. Also you have to get enough protein in your diet to be able to heal. Someone should be monitoring your diet.

 

When we eat the Standard American Diet with processed foods and vitamin enriched foods, it's not as much of an issue to be worried about getting the right supplementation. Once your are eating whole foods, and dealing with malabsorption and malnutrition, it's critical to get the right balance of the right supplements and nutrition.

 

Don't wait on this. You are feeling terrible because something is off and you need to get it solved. See a professional who can get you on the right track. A Celiac has more than gastrointestinal issues, your brain is affected too, it's hard to think clearly. My brain fog has made it necessary for me to have family help me stay on track.

 

Is there someone who can help you find the right professional - your parents, a relative, a friend, someone near you in the same city who can help you? Get help with this. Don't try to do it alone.

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Yea I looked at that one too until I read the ingrediants. I'm taking the DIgestive Advantage Constipation Formula which doesn't contain gluten or dairy. It's the only thing that keeps me away from laxatives /:

 

Juicing green veggies is all that keeps me from constipation...not being used to the 'green' taste, I bought a basic juicer, and along with Romaine Lettuce, Head Lettuce, carrots, green peppers, cucumbers, celery, kale, red chard, asparagus, sugar snap peas, tomatoes, avocado, and mustard leaves (someof this stuff has to be processed with a food processor before being juiced - use plain cucumber juice with soft leaved veggies, process, then juice the remains), but to keep it palatable I added apples, pears and grapes to taste.  Then, I slowly reduced the fruits, until I could handle the just the veggies.  And as long as I drink 4 cups a day of the juice, I have smooth bowels that don't hurt, and don't burn, although they do look a bit green. I do not use a juice that eliminates all pulp, since it is the soft fiber bits that keep me going.  Your juice should be a little bit smoothie/creamy in texture from the avocados and fruit, not just watery juice, and the natural oils there are great for you too.

 

I had to go off the fruit additives because of Type II Diabetes, and reluctance to take insulin or any other drugs I can avoid...technically my diabetes is food controllable, if a tad high overall (120 average).

 

Now, I am so hooked on the veggie juice, I dislike not having it as part of my diet, and when I run out, two days later my stools are stones again.

 

Worth a try.

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Juicing green veggies is all that keeps me from constipation...not being used to the 'green' taste, I bought a basic juicer, and along with Romaine Lettuce, Head Lettuce, carrots, green peppers, cucumbers, celery, kale, red chard, asparagus, sugar snap peas, tomatoes, avocado, and mustard leaves (someof this stuff has to be processed with a food processor before being juiced - use plain cucumber juice with soft leaved veggies, process, then juice the remains), but to keep it palatable I added apples, pears and grapes to taste.  Then, I slowly reduced the fruits, until I could handle the just the veggies.  And as long as I drink 4 cups a day of the juice, I have smooth bowels that don't hurt, and don't burn, although they do look a bit green. I do not use a juice that eliminates all pulp, since it is the soft fiber bits that keep me going.  Your juice should be a little bit smoothie/creamy in texture from the avocados and fruit, not just watery juice, and the natural oils there are great for you too.

 

I had to go off the fruit additives because of Type II Diabetes, and reluctance to take insulin or any other drugs I can avoid...technically my diabetes is food controllable, if a tad high overall (120 average).

 

Now, I am so hooked on the veggie juice, I dislike not having it as part of my diet, and when I run out, two days later my stools are stones again.

 

Worth a try.

Also, I add in liquid vitimins...ionic calcium, zinc, magnesium, potassium, liquid daily vitamins including all B's, and liquid trace minerals... yet I can tell I am mal-absorptive just by my nails...I eats tons of protein, and yet my nails show Onychorrexis, Median Nail Dystropy; Leukonychia, and more that I can't spell!  I'm only on Day 4 of no gluten, so it will be a long while before I show some signs of healing.

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lol no obviously not a hundred :P But I do take a lot.

 I'm taking a supplement caleld DIgestive Advantage Constipation formula which helps me stay somewhat regular. I take a fish oil pill. A probiotic (acidophilus). Digestive enzymes with every meal. L-Glutamine on it's own, and also something called G.I. Revive powder which also contains L-Glutamine along with glucosamine, citris pectin, aloe vera, slippery elm, marshmallow, mucin, chamomille, okra extract, cat's claw, msm, prune powder, and zinc. I've heard many good things about the GI Revive which I just odered about a week ago, so I guess it's too soon to tell if it'll help. I also take regular vitamins (which yes are gluten-free....i know some of you are going to ask that)

 

You might want to have a look at this: http://www.biomedcentral.com/1741-7015/11/222

A supplement might not contain what's on the label.

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Hi AnnaChristine , I hope you don't mind me suggesting something ,

to help you find out what's bothering you ,

You need to stop all those supplements ,

Keep it simple

Start again

using good whole foods to heal , boiled white rice, fish, meat veggies fruits ,a little gluten-free bread too if it agrees ,

Then get all your vitamin and mineral levels tested properly by a celiac Doctor

before you take anything else

Hope you don't mind my saying

Jiggles x x

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Hi AC18,

 

The last time I got glutened good it took about 6 weeks for the symptoms to fade,  So you are getting close to that time since you were glutened.  Just a thot.

Hi there,  I couldn't help but see this and want to ask you.  6 weeks?  A lot of people say they feel symptoms for a few days, a week.  But I started feeling symptoms on April 30 and although I'm now finally seeing improvement, that's over 3 weeks.  I thought I was the only one with this long tortured thing going on.  Any thoughts on why it would take so long?  Do your symptoms start out bad and then gradually get better over that time? 

 

Thanks!

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It's not unheard of for symptoms to last 3 weeks or so.  The immune system ramps up when glutened.  It takes time for it to settle down.  With some of us, if we get hit, all kinds of things happen, all the other AI stuff starts up, everything aches, headaches, etc.  It;s not just bowel issues.  

 

Your not alone,

 

Colleen

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It's not unheard of for symptoms to last 3 weeks or so.  The immune system ramps up when glutened.  It takes time for it to settle down.  With some of us, if we get hit, all kinds of things happen, all the other AI stuff starts up, everything aches, headaches, etc.  It;s not just bowel issues.  

 

Your not alone,

 

Colleen

Thanks Colleen...it helps to hear that.

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It's not unheard of for symptoms to last 3 weeks or so.  The immune system ramps up when glutened.  It takes time for it to settle down.  With some of us, if we get hit, all kinds of things happen, all the other AI stuff starts up, everything aches, headaches, etc.  It;s not just bowel issues.  

 

Your not alone,

 

Colleen

3 weeks? I said FIVE MONTHS

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Hi there,  I couldn't help but see this and want to ask you.  6 weeks?  A lot of people say they feel symptoms for a few days, a week.  But I started feeling symptoms on April 30 and although I'm now finally seeing improvement, that's over 3 weeks.  I thought I was the only one with this long tortured thing going on.  Any thoughts on why it would take so long?  Do your symptoms start out bad and then gradually get better over that time? 

 

Thanks!

WHy do people keep saying "3 weeks" Ive been gluten free, and paleo for five months! And I feel WORSE

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WHy do people keep saying "3 weeks" Ive been gluten free, and paleo for five months! And I feel WORSE

Because she is talking about HER experience? There are others on here trying to share their experiences with the thought that it might be helpful to you. That's part of a forum.

If being " paleo" makes you feel bad, maybe you shouldn't do that diet?

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WHy do people keep saying "3 weeks" Ive been gluten free, and paleo for five months! And I feel WORSE

AnnaChristine...I'm sorry to have upset you. I was responding to someone who mentioned glutening symptoms lasting for 6 weeks. It was not meant to upset you. I hope that you feel better soon.

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WHy do people keep saying "3 weeks" Ive been gluten free, and paleo for five months! And I feel WORSE

 

AnnaChristine, the 3 weeks, 6 weeks references that are being confused with your original posts are from other people on the thread trying to tell you how long just a single dose of gluten can set you back, and that is if you are stable.

 

You aren't stable...you don't even know which foods you are reacting to, or how bad your system has gotten screwed up.  Taking lots of supplements is hard on the Upper GI, and the damaged Upper GI will absorb only a little of them.  The Naturalists and Nutritionists would tell you to take some of the basic minerals and vitamins you are missing, and keep raising the dose until you absorb something from them.  Your Upper GI isn't absorbing much from what you eat.

 

As to your foods, Paleo is wonderful, but your body is screaming there is something not being fixed just by going off of gluten, dairy, and everything that is any fun to eat.

 

Your body is telling you that what you are eating is not working, and that your supplements are not doing the job either.  You must simplify what you are eating and absorbing, so you body can rest and heal.  Yes, you need to stay off gluten, and dairy, and anything not produced by a plant or the animals that eat the plants for the time being.  But you are not listening to your body.  It doesn't like something that you are doing, and there is a lot of things besides gluten that can irritate your insides.

 

What are your main symptoms...the top three symptoms that are making you miserable?  Is it Diarrhea and Bloating...Constipation and Bloating...Stomach cramps?  What is it that you can isolate as a problem?  What foods can you get down, that will stay down, and not give your symptoms?  If you are eating a wide variety of food, you cannot tell what is triggering your symptoms except the knowledge that gluten is a big cause.  Fine, you are off gluten...you don't eat processed food...you have a seperate kitchen, so there is no cross contamination.

 

So something you are eating is hurting you on top of your Celiac.  Or something you are not eating is a problem.  But until you narrow down your food list, and eat the exact same foods every day for a while, you cannot figure it out.

 

It would also help if you ate a single food at a time, and waited for a reaction before eating something else a couple of hours later.  We react to food quickly because we have messed up digestion, but you cannot locate a pattern if you keep changing what you are putting inside your body every few weeks.

 

You keep adding things by supplements, and you don't know if there is something in there irritating you either.

 

Please, go back to the beginning.  Choose a handful of things to eat for several weeks, or even months, and don't change them.  Take your vitimins and minerals.  Avoid gluten of course, and anything you think will be bad for you, but stop throwing everything at your body at once, trying to get it fixed.  Simplify what you eat, eat it over and over, and listen to your body. 

 

We all want to pick you up, and get you fixed, but we can't.  Only you can fix you...we can tell you what to watch out for, or what we did, but you are the scientist AND the guinea pig.  You have to get logical and practical about this, and stop trying to magically fix yourself with a potion!  You body needs time to heal...and you need to take the time to study yourself.

 

It will get better, you will get well, and you will have done it.  I will help you.  Everyone here will help you. But you have to do it, and now that you know what you have been doing isn't helping you heal properly, you have to find out what else is the problem!

 

Start over, keep it simple, and repeat until you figure out which of the foods you are eating is hurting you.

 

And many hugs being sent to you.XXXXX

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Hi there,  I couldn't help but see this and want to ask you.  6 weeks?  A lot of people say they feel symptoms for a few days, a week.  But I started feeling symptoms on April 30 and although I'm now finally seeing improvement, that's over 3 weeks.  I thought I was the only one with this long tortured thing going on.  Any thoughts on why it would take so long?  Do your symptoms start out bad and then gradually get better over that time? 

 

Thanks!

 

HI Icelandgirl,

 

Yes, my symptoms start out bad and decrease over time.   Why the length of time?  Well, the immune system wants to keep us safe from invading germs.  So it keeps making antibodies for a while after they are needed.  And the antibodies don't die off instantly also.  So the effects can last a while after a glutening.  I was talking about physical symptoms, but damage isn't always felt and could be going on longer than that.  One study a while back showed negative changes in the gut lining remained after 18 months on a gluten-free diet for some people.   It's not an instant fix to  repair the gut.  But we are gluten-free for life so it happens when it does.  :)

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    Adjust seasoning with salt and pepper, as desired. 
    Serve is a bowl with tortilla chips and guacamole.

    Dr. Ron Hoggan, Ed.D.
    Celiac.com 06/15/2018 - There seems to be widespread agreement in the published medical research reports that stuttering is driven by abnormalities in the brain. Sometimes these are the result of brain injuries resulting from a stroke. Other types of brain injuries can also result in stuttering. Patients with Parkinson’s disease who were treated with stimulation of the subthalamic nucleus, an area of the brain that regulates some motor functions, experienced a return or worsening of stuttering that improved when the stimulation was turned off (1). Similarly, stroke has also been reported in association with acquired stuttering (2). While there are some reports of psychological mechanisms underlying stuttering, a majority of reports seem to favor altered brain morphology and/or function as the root of stuttering (3). Reports of structural differences between the brain hemispheres that are absent in those who do not stutter are also common (4). About 5% of children stutter, beginning sometime around age 3, during the phase of speech acquisition. However, about 75% of these cases resolve without intervention, before reaching their teens (5). Some cases of aphasia, a loss of speech production or understanding, have been reported in association with damage or changes to one or more of the language centers of the brain (6). Stuttering may sometimes arise from changes or damage to these same language centers (7). Thus, many stutterers have abnormalities in the same regions of the brain similar to those seen in aphasia.
    So how, you may ask, is all this related to gluten? As a starting point, one report from the medical literature identifies a patient who developed aphasia after admission for severe diarrhea. By the time celiac disease was diagnosed, he had completely lost his faculty of speech. However, his speech and normal bowel function gradually returned after beginning a gluten free diet (8). This finding was so controversial at the time of publication (1988) that the authors chose to remain anonymous. Nonetheless, it is a valuable clue that suggests gluten as a factor in compromised speech production. At about the same time (late 1980’s) reports of connections between untreated celiac disease and seizures/epilepsy were emerging in the medical literature (9).
    With the advent of the Internet a whole new field of anecdotal information was emerging, connecting a variety of neurological symptoms to celiac disease. While many medical practitioners and researchers were casting aspersions on these assertions, a select few chose to explore such claims using scientific research designs and methods. While connections between stuttering and gluten consumption seem to have been overlooked by the medical research community, there is a rich literature on the Internet that cries out for more structured investigation of this connection. Conversely, perhaps a publication bias of the peer review process excludes work that explores this connection.
    Whatever the reason that stuttering has not been reported in the medical literature in association with gluten ingestion, a number of personal disclosures and comments suggesting a connection between gluten and stuttering can be found on the Internet. Abid Hussain, in an article about food allergy and stuttering said: “The most common food allergy prevalent in stutterers is that of gluten which has been found to aggravate the stutter” (10). Similarly, Craig Forsythe posted an article that includes five cases of self-reporting individuals who believe that their stuttering is or was connected to gluten, one of whom also experiences stuttering from foods containing yeast (11). The same site contains one report of a stutterer who has had no relief despite following a gluten free diet for 20 years (11). Another stutterer, Jay88, reports the complete disappearance of her/his stammer on a gluten free diet (12). Doubtless there are many more such anecdotes to be found on the Internet* but we have to question them, exercising more skepticism than we might when reading similar claims in a peer reviewed scientific or medical journal.
    There are many reports in such journals connecting brain and neurological ailments with gluten, so it is not much of a stretch, on that basis alone, to suspect that stuttering may be a symptom of the gluten syndrome. Rodney Ford has even characterized celiac disease as an ailment that may begin through gluten-induced neurological damage (13) and Marios Hadjivassiliou and his group of neurologists and neurological investigators have devoted considerable time and effort to research that reveals gluten as an important factor in a majority of neurological diseases of unknown origin (14) which, as I have pointed out previously, includes most neurological ailments.
    My own experience with stuttering is limited. I stuttered as a child when I became nervous, upset, or self-conscious. Although I have been gluten free for many years, I haven’t noticed any impact on my inclination to stutter when upset. I don’t know if they are related, but I have also had challenges with speaking when distressed and I have noticed a substantial improvement in this area since removing gluten from my diet. Nonetheless, I have long wondered if there is a connection between gluten consumption and stuttering. Having done the research for this article, I would now encourage stutterers to try a gluten free diet for six months to see if it will reduce or eliminate their stutter. Meanwhile, I hope that some investigator out there will research this matter, publish her findings, and start the ball rolling toward getting some definitive answers to this question.
    Sources:
    1. Toft M, Dietrichs E. Aggravated stuttering following subthalamic deep brain stimulation in Parkinson’s disease--two cases. BMC Neurol. 2011 Apr 8;11:44.
    2. Tani T, Sakai Y. Stuttering after right cerebellar infarction: a case study. J Fluency Disord. 2010 Jun;35(2):141-5. Epub 2010 Mar 15.
    3. Lundgren K, Helm-Estabrooks N, Klein R. Stuttering Following Acquired Brain Damage: A Review of the Literature. J Neurolinguistics. 2010 Sep 1;23(5):447-454.
    4. Jäncke L, Hänggi J, Steinmetz H. Morphological brain differences between adult stutterers and non-stutterers. BMC Neurol. 2004 Dec 10;4(1):23.
    5. Kell CA, Neumann K, von Kriegstein K, Posenenske C, von Gudenberg AW, Euler H, Giraud AL. How the brain repairs stuttering. Brain. 2009 Oct;132(Pt 10):2747-60. Epub 2009 Aug 26.
    6. Galantucci S, Tartaglia MC, Wilson SM, Henry ML, Filippi M, Agosta F, Dronkers NF, Henry RG, Ogar JM, Miller BL, Gorno-Tempini ML. White matter damage in primary progressive aphasias: a diffusion tensor tractography study. Brain. 2011 Jun 11.
    7. Lundgren K, Helm-Estabrooks N, Klein R. Stuttering Following Acquired Brain Damage: A Review of the Literature. J Neurolinguistics. 2010 Sep 1;23(5):447-454.
    8. [No authors listed] Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 43-1988. A 52-year-old man with persistent watery diarrhea and aphasia. N Engl J Med. 1988 Oct 27;319(17):1139-48
    9. Molteni N, Bardella MT, Baldassarri AR, Bianchi PA. Celiac disease associated with epilepsy and intracranial calcifications: report of two patients. Am J Gastroenterol. 1988 Sep;83(9):992-4.
    10. http://ezinearticles.com/?Food-Allergy-and-Stuttering-Link&id=1235725 
    11. http://www.craig.copperleife.com/health/stuttering_allergies.htm 
    12. https://www.celiac.com/forums/topic/73362-any-help-is-appreciated/
    13. Ford RP. The gluten syndrome: a neurological disease. Med Hypotheses. 2009 Sep;73(3):438-40. Epub 2009 Apr 29.
    14. Hadjivassiliou M, Gibson A, Davies-Jones GA, Lobo AJ, Stephenson TJ, Milford-Ward A. Does cryptic gluten sensitivity play a part in neurological illness? Lancet. 1996 Feb 10;347(8998):369-71.

    Jefferson Adams
    Celiac.com 06/14/2018 - Refractory celiac disease type II (RCDII) is a rare complication of celiac disease that has high death rates. To diagnose RCDII, doctors identify a clonal population of phenotypically aberrant intraepithelial lymphocytes (IELs). 
    However, researchers really don’t have much data regarding the frequency and significance of clonal T cell receptor (TCR) gene rearrangements (TCR-GRs) in small bowel (SB) biopsies of patients without RCDII. Such data could provide useful comparison information for patients with RCDII, among other things.
    To that end, a research team recently set out to try to get some information about the frequency and importance of clonal T cell receptor (TCR) gene rearrangements (TCR-GRs) in small bowel (SB) biopsies of patients without RCDII. The research team included Shafinaz Hussein, Tatyana Gindin, Stephen M Lagana, Carolina Arguelles-Grande, Suneeta Krishnareddy, Bachir Alobeid, Suzanne K Lewis, Mahesh M Mansukhani, Peter H R Green, and Govind Bhagat.
    They are variously affiliated with the Department of Pathology and Cell Biology, and the Department of Medicine at the Celiac Disease Center, New York Presbyterian Hospital/Columbia University Medical Center, New York, USA. Their team analyzed results of TCR-GR analyses performed on SB biopsies at our institution over a 3-year period, which were obtained from eight active celiac disease, 172 celiac disease on gluten-free diet, 33 RCDI, and three RCDII patients and 14 patients without celiac disease. 
    Clonal TCR-GRs are not infrequent in cases lacking features of RCDII, while PCPs are frequent in all disease phases. TCR-GR results should be assessed in conjunction with immunophenotypic, histological and clinical findings for appropriate diagnosis and classification of RCD.
    The team divided the TCR-GR patterns into clonal, polyclonal and prominent clonal peaks (PCPs), and correlated these patterns with clinical and pathological features. In all, they detected clonal TCR-GR products in biopsies from 67% of patients with RCDII, 17% of patients with RCDI and 6% of patients with gluten-free diet. They found PCPs in all disease phases, but saw no significant difference in the TCR-GR patterns between the non-RCDII disease categories (p=0.39). 
    They also noted a higher frequency of surface CD3(−) IELs in cases with clonal TCR-GR, but the PCP pattern showed no associations with any clinical or pathological feature. 
    Repeat biopsy showed that the clonal or PCP pattern persisted for up to 2 years with no evidence of RCDII. The study indicates that better understanding of clonal T cell receptor gene rearrangements may help researchers improve refractory celiac diagnosis. 
    Source:
    Journal of Clinical Pathologyhttp://dx.doi.org/10.1136/jclinpath-2018-205023

    Jefferson Adams
    Celiac.com 06/13/2018 - There have been numerous reports that olmesartan, aka Benicar, seems to trigger sprue‐like enteropathy in many patients, but so far, studies have produced mixed results, and there really hasn’t been a rigorous study of the issue. A team of researchers recently set out to assess whether olmesartan is associated with a higher rate of enteropathy compared with other angiotensin II receptor blockers (ARBs).
    The research team included Y.‐H. Dong; Y. Jin; TN Tsacogianis; M He; PH Hsieh; and JJ Gagne. They are variously affiliated with the Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School in Boston, MA, USA; the Faculty of Pharmacy, School of Pharmaceutical Science at National Yang‐Ming University in Taipei, Taiwan; and the Department of Hepato‐Gastroenterology, Chi Mei Medical Center in Tainan, Taiwan.
    To get solid data on the issue, the team conducted a cohort study among ARB initiators in 5 US claims databases covering numerous health insurers. They used Cox regression models to estimate hazard ratios (HRs) and 95% confidence intervals (CIs) for enteropathy‐related outcomes, including celiac disease, malabsorption, concomitant diagnoses of diarrhea and weight loss, and non‐infectious enteropathy. In all, they found nearly two million eligible patients. 
    They then assessed those patients and compared the results for olmesartan initiators to initiators of other ARBs after propensity score (PS) matching. They found unadjusted incidence rates of 0.82, 1.41, 1.66 and 29.20 per 1,000 person‐years for celiac disease, malabsorption, concomitant diagnoses of diarrhea and weight loss, and non‐infectious enteropathy respectively. 
    After PS matching comparing olmesartan to other ARBs, hazard ratios were 1.21 (95% CI, 1.05‐1.40), 1.00 (95% CI, 0.88‐1.13), 1.22 (95% CI, 1.10‐1.36) and 1.04 (95% CI, 1.01‐1.07) for each outcome. Patients aged 65 years and older showed greater hazard ratios for celiac disease, as did patients receiving treatment for more than 1 year, and patients receiving higher cumulative olmesartan doses.
    This is the first comprehensive multi‐database study to document a higher rate of enteropathy in olmesartan initiators as compared to initiators of other ARBs, though absolute rates were low for both groups.
    Source:
    Alimentary Pharmacology & Therapeutics