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Jennifersvista

Questions about the leaky gut urine test

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Hi everyone.  I just received my test kit and I was just wondering about the mannitol/lactulose solution you have to drink.  How bad does it taste?  It's a tiny bit of so,union I am supposed to mix in water.  Does it have to be mixed in water or could it be out in juice or tea?   Also did anyone have any side effects from it such as diarrhea or cramping??   Thanks. 

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I'd not heard of this test until I read your post. I did google it and you may want to read this: 

http://labtestsonline.org.uk/understanding/analytes/unvalidated-tests/intestinal-permeability/

mainly to make sure that you don't forgo celiac testing if you've not already undergone it, which was the concern of the researchers in this study: http://www.ncbi.nlm.nih.gov/pubmed/9071934

Best of luck and do post what it tastes like and your results, I'm sure others will also be interested :)

 

 

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I think I had the blood test done for celiac several years ago.  It was negative.  Is celiac still tested through blood?   Do you think I should be tested for it again before I do this gut permeability test?  I read your link.  Thanks for sharing.  I feel that most main stream physicians don't test for a lot of things that naturopaths do.  I was told I had IBS 20 years ago.  What I am experiencing now is much different than my typical IBS symptoms.  I need to get to the bottom of this.  I feel awful most days with some days feeling ok.  Sticky poops and some diarrhea but never normal.  Lots of back pain associated with bm's.  Which is also a fairly new symptom.   Also severe itching just on my torso areas.  But no real stomach pain.  No bad cramping.  I can't figure it out.  I took an antibiotic for a bladder infection once and my symptoms improved for about 4 months.  It was great.  So then I thought I had sibo but my test didn't show enough bacteria.  Any help or advice you can offer I'd appreciate.  

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10 minutes ago, Jennifersvista said:

 Is celiac still tested through blood?   Do you think I should be tested for it again before I do this gut permeability test?

Yes, a blood test and then if positive an endoscopy (camera down throat) with biopsies taken of the intestine to confirm. You'd need to be eating gluten for it to work however and whether to go through the process is something only you can decide upon. 

There's an faq stickied above and I had my own go at collecting some links and generic answers here: 

 

Of course doing the permeability test wont affect testing so you can go ahead and do that. 

There's also nothing to stop you going gluten free and seeing if that helps, just dont do it if you plan on testing for celiac. Indeed eliminating that as a possibility should really come first as once you eliminate gluten it can be unpleasant to go back on it for testing purposes. 

Best of luck :)

 

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This is what you'll have to do if you go off gluten prior to blood testing or endoscopy.

http://www.cureceliacdisease.org/faq/what-is-a-gluten-challenge/

Even though you had the test years ago, celiac disease can present at any time so just b/c you were negative then doesn't mean you will be negative now. Besides that, we don't know what tests you had back then -- the full panel or not. 

Here is the full celiac serum panel:

Anti-Gliadin (AGA) IgA
Anti-Gliadin (AGA) IgG
Anti-Endomysial (EMA) IgA
Anti-Tissue Transglutaminase (tTG) IgA
Deamidated Gliadin Peptide (DGP) IgA and IgG
Total Serum IgA 

 


Also can be termed this way:

Endomysial Antibody IgA
Tissue Transglutaminase IgA 
GLIADIN IgG
GLIADIN IgA
Total Serum IgA 
Deamidated Gliadin Peptide (DGP) IgA and IgG

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I firmly believe in "leaky gut". Even Dr. A. Fasano, a leading celiac researcher (Ped GI) at Harvard/MA General discovered Zonulin which may be contributing to leaky gut.  But.....that is as far as science has gone.  There is so much we do not know yet.

 

You should consider a celiac retest.  Ask for the entire panel.  Why?  I am one of the celiacs who did not get a positive on the more commonly used celiac test (Ttg).  Luckily, mynGI ordered the entire panel or my diagnosis would have been missed.  My biopsies revealed moderate to severe intestinal damage.  

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My advice is is always get and retain copies of all lab tests.  Keep notes on doctor visits and outcomes.  I have kept 20 years of records.  My new doctors love it.  I also put a family medical history (first names only) for my extended family.  It has helped so many!  

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