Intestinal Inflammation

[BarryC 7]

It took me a long time to finally realise that I am gluten intolerant, thankfully not full blown celiac. I have had digestive issues all my life, and with a family history of colorectal cancer, am quite obsessed. Over the last few years I have gone from gluten intolerant, carbohydrate intoilerant, fat intolerant, IBS, GERD, gastritis, functional dyspepsia. I have symptoms of all. The one symptom in common is abdominal distension, that is worse after eating carbs and fatty foods.. The only thing that ever worked was gluten free, but I could never keep it up. Two weeks ago I woke up sick to my stomach, bloated, and sore all over.  The worst I EVER felt in my life (I am 58). The only thing I could think of was the week before I ate a lot of gluten containing carbs. Also had a few drinks and some wings and pizza. Didnt go overboard at all-never do. I decided to try the gluten free thing again and do more research. I discovered that for intolerants, gluten irritates the intestines, resulting in pain and bloating, and causing food malabsorption.  Fatty foods, alcohol, and coffee are major irritants and their effects are much worse with gluten inflamed intestines. Voila! I think I found it! Good news is after a few weeks, depending on the amount of damage, and abstaining from problem foods, your intestines can get back to normal. Tell me friends, does this sound about right? Thanks for the help, and God Bless you and yours!

[Jmg 300]

Hi Barry,

One question occurred

:

4 hours ago, BarryC said:

The only thing that ever worked was gluten free

Did you undergo celiac testing and have a doctor exclude it via a full blood panel and / or endoscopy, or was this something you did yourself? If the latter then: 

4 hours ago, BarryC said:

Over the last few years I have gone from gluten intolerant, carbohydrate intoilerant, fat intolerant, IBS, GERD, gastritis, functional dyspepsia. I have symptoms of all. The one symptom in common is abdominal distension, that is worse after eating carbs and fatty foods..

all of your symptoms and conditions may actually be one condition. Which would fit with you saying that the only thing which worked was going gluten free, and more significantly perhaps with your familial history of cancer. 

As for this:

4 hours ago, BarryC said:

I discovered that for intolerants, gluten irritates the intestines, resulting in pain and bloating, and causing food malabsorption.  Fatty foods, alcohol, and coffee are major irritants and their effects are much worse with gluten inflamed intestines. Voila! I think I found it! Good news is after a few weeks, depending on the amount of damage, and abstaining from problem foods, your intestines can get back to normal. Tell me friends, does this sound about right

I guess it depends where you do your research. My understanding is that there are three groups who have an issue with gluten. Food malabsorbtion in celiacs comes about through the destruction of the vili, not simply inflammation in the gut. Recovery may take far longer than a few weeks. 

I'm non celiac gluten sensitive. I tested negative on a limited blood panel and 4 biopsies taken during endoscopy failed to show evidence of celiac. However I reacted very positively to the gluten free diet and adhering to it largely resolved a lot of different seemingly unconnected symptoms. However if I eat a tiny amount of gluten they can come back. This is because my auto immune system see's gluten as an invader and starts attacking my own body if I eat any. That means that antibodies are created and they will be at work damaging different parts of my system long after all the gluten has gone. 

The important thing to remember here is that it's not just the intestines that are damaged. The barrier between the gut and the blood can be affected and that allows gluten damage to spread across the body. In my case the impact is largely neurological. 

There's a lot more I could say but really my first question is the important one. Have you checked this out properly? There's a lot of rubbish out there on different websites and some of them are telling people what they want to hear. Yes you can have a little bit of gluten once your system is healed etc. If you can then great, but be sure you understand exactly how gluten is interacting with your body first!

[Ennis_TX 819]

Look into Ulcerative colitis, I have it on top of Celiac, it explains a lot of the issues with the distention, carbs, and fats. Flare ups are caused by Gluten, Dairy, Fructose, Glucose and other common sugars found in carbs.

[Guest]

finally i would like to share some of experience Patients with ulcerative colitis and Crohn's infection are at expanded hazard for creating colorectal malignancy (CRC). Incessant aggravation is accepted to advance carcinogenesis. The hazard for colon disease increments with the term and anatomic degree of colitis and nearness of other fiery issue, (for example, essential sclerosing cholangitis), while it diminishes when patients take medications to decrease irritation, (for example, mesalamine and steroids). The hereditary elements that prompt sporadic CRC-chromosome precariousness, microsatellite shakiness, and DNA hypermethylation-likewise happen in colitis-related CRC. Dissimilar to the ordinary colonic mucosa, cells of the aggravated colonic mucosa have these hereditary adjustments before there is any histologic confirmation of dysplasia or growth. The explanations behind these distinctions are not known, but rather oxidative anxiety is probably going to be included. Receptive oxygen and nitrogen species created by incendiary cells can influence control of qualities that encode variables that avert carcinogenesis, (for example, p53, DNA jumble repair proteins, and DNA base extraction repair proteins), interpretation elements, (for example, atomic component κB), or flagging proteins, (for example, cyclooxygenases). Organization of operators that cause colitis in sound rodents or hereditarily built, growth inclined mice quickens improvement of colorectal tumors. Mice hereditarily inclined to incendiary entrail malady additionally create CRC, particularly within the sight of bacterial colonization. Singular segments of the intrinsic and versatile resistant reaction have likewise been embroiled in carcinogenesis. These perceptions offer convincing backing for the part of irritation in colon carcinogenesis.