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Scott Adams

Is a Reovirus Infection a Prime Cause of Celiac Disease?

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Is a reovirus infection a prime cause of celiac disease? Researchers have suspected that viral infections may play a major role in celiac disease by  causing a pathological responses that triggers T helper 1 (TH1) immunity against dietary gluten.

A team of researchers recently set out to test this hypothesis and to gain insights into mechanisms underlying virus-induced loss of tolerance to dietary antigens. To do so, they developed a viral infection model that makes use of two reovirus strains that infect the intestine, but which differ in their immunopathological outcomes.

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