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- Aretaeus Cappadocia commented on Jefferson Adams's article in Origins of Celiac Disease8Celiac Disease Linked to Neanderthal Ancestry
From the original post: "Some indicate negative effects, with putative links to various diseases as measured by genome-wide association studies (Sankararaman et al. 2014. Simonti et al. 2016)." ---> The links in the original post lead to a different article. I think these might be the correct links: "The landscape of Neandertal ancestry in present...- celiac
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- Aretaeus Cappadocia commented on Jefferson Adams's article in Diagnosis, Testing & Treatment4
Scientists Make Major Advance in Autoimmune Disease Therapy
The main use for leukapheresis is to mitigate (not cure) certain blood disorders, particulary certain types of blood cancer. It's kind of like "thinning the herd" when your body makes too many white blood cells. Doesn't fix the underlying problem, but it buys some time. The car-T people utilize the same technology to collect enough T cells (a type of...- autoimmune
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- Scott Adams commented on Scott Adams's article in Additional Concerns8This Common Blood Pressure Drug Can Mimic Celiac Disease Symptoms
Olmesartan is the ARB most strongly linked to sprue-like enteropathy, a condition that can closely mimic celiac disease with diarrhea, weight loss, villous atrophy, and often negative celiac blood tests. Some newer reports suggest this reaction may not be limited to olmesartan and could represent a possible ARB class effect, with cases reported for drugs...- blood pressure medication
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- Lotte18 commented on Jefferson Adams's article in Diagnosis, Testing & Treatment4Scientists Make Major Advance in Autoimmune Disease Therapy
So I just looked up leukapheresis. The Cleveland Clinic site states that this does not cure blood disorders. It's used to remove and then replace white blood cells that have reproduced uncontrollably, ie cancer. But maybe that information is not up to date? Anyway, it looks daunting.- autoimmune
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0May 12, 2026 10:30 PM
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By Wheatwacked · Posted
Chronic fatigue in the producer was the inspiration for the episode but I feel it touches on anyone that suffers and is dismissed as psycosomatic. The patient expressed my feelings elequently. In episode 2 the doctor explains the problem well. I stopped all commercial milk protein like skim milk added to processed foods and in a few days there was a definate improvement in my gut, bowel movements, discomfort etc. Still drinking several glasses of Pasture Fed grass fed milk with no negative effects. Specifically, for myself Clonidine is the only medication that lowers my BP and the doctor did not renew it, insisting that I continue Losartan. I think that she thinks I am abusing Clonidine and the reason the Losartan doesn't work is because I am non-compliant. Absolutely not. Surprisingly after a few days withdrawal from the Clonidine my fasting blood sugar has gotten under control. Fasting blood sugar near normal instead of over 160. Last few days its been below 100. I still need Glimiperide. Without the clonidine my pulse rate is around 100 bpm, with it around 60. Prescription of angiotensin receptor blockers in celiac disease is associated with persistent symptoms and surrogate markers of malabsorption. https://pmc.ncbi.nlm.nih.gov/articles/PMC12323722/ Angiotensin receptor blocker-associated enteropathy (ARB-e) is an increasingly recognised clinical entity with symptoms and histological findings identical to coeliac disease (celiac disease). There is evidence to suggest immune-mediated mucosal injury in ARB-e with a high prevalence of DQ2/DQ8; however, as IgA anti-tissue transglutaminase (anti-TTG) is usually negative https://onlinelibrary.wiley.com/doi/full/10.1002/ueg2.12117 NEW research [Nov 2024] presented at the American College of Gastroenterology (ACG) Annual Scientific Meeting suggests that angiotensin receptor blockers (ARBs), a class of drugs commonly used to manage hypertension, may be associated with poorer outcomes in patients with coeliac disease. Findings indicated that patients taking ARBs had a higher likelihood of experiencing persistent symptoms and markers of poor small bowel healing, such as anaemia and iron deficiency. https://www.emjreviews.com/en-us/amj/gastroenterology/news/angiotensin-receptor-blockers-may-worsen-coeliac-disease-outcomes/ -
By mermaidluver22 · Posted
@BarcinoHi! I am so sorry abt your son but also relieved to know I am not alone! My ttg iga is still mildly elevated but going down. Last time we checked I had some small erosions in my ileum but recently got an MRE that showed no inflammation. Calpro 70. We are still in limbo but we are taking a conservative approach as well. Please keep me updated about his situation and outcomes! I always love to hear others opinions/experiences especially ibd specialists. -
By Scott Adams · Posted
Celiac.com has published a book on our site by Jean Duane PhD called Gluten-Centric Culture, which covers many of the social aspects of having celiac disease: This chapter in particular covers issues around eating with family and others - Gluten-Centric Culture: Chapter 5 - Grabbing A Bite Together: -
By BelleDeJour · Posted
Oh, thank you all so so much! I have found my people. ❤️ I am so sorry that we have all suffered with this torturous itching and resulting sore skin. Sue, I can relate to what you wrote about the dark thoughts, I have had them, too. It's very tough and painful. I have now had a 2 day straight run of only minor itching. I woke up this morning and did not want to get out of bed because it is the first time in months that I have felt comfortable and actually been able to appreciate the lovely feeling of the duvet on my skin, rather than just waking in pain and thinking about where I need to put cream on before I dress for work. If I can continue like this, then I think I could manage without medication but every time I say this, I then have a flare up. I plan to be very careful about what I eat over the weekend and it won't be easy as we are out with friends for dinner on Saturday (the pub do have very good gluten-free options, I checked of course!). I really, REALLY appreciate your words so much and am so glad to have found this forum. I am going to read the articles kindly posted now, thank you Scott. -
By Scott Adams · Posted
I don’t know how common this is with celiac disease specifically, but significant inflammation, weight changes, aging, genetics, and skin elasticity can all play a role. It may be worth talking with both your doctor and a board-certified dermatologist or plastic surgeon to see what options are realistic, from skin-tightening treatments to surgical approaches, while also making sure there isn’t ongoing inflammation, thyroid imbalance, or nutritional deficiency contributing. You deserve support for both the physical and emotional side of this.
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