@Sammy Web, PPI's like Omeprazole suppresses your ability to produce antibodies to gluten.  So if you had the tests done while you were taking Omeprazole, the tests won't be accurate.   Omeprazole will cause villus damage.  Not all the damage in Celiac is visible to the naked eye, especially in the early stages.  Damage to the intestines can be microscopic.  Were biopsies taken to look for microscopic changes?  You would be wise to stay off the Omeprazole, redo the gluten challenge and get tested again.  

herminia, Omeprazole may mask some of the symptoms of celiac disease but it will not prevent the damage being done to the villous lining of your small bowel that defines the disease. You seem not to be taking that very seriously.

Such a confusing disease! I tested positive with both tg tests so I have been taking Omeprazole for years with good results, although for several months now am experiencing increased nausea and pain on a daily basis and have added ondansatron for "those" days. Low-grade pain in left abdominal quadrant is a daily constant, and doctors have not taken interest in that aspect. I do my best to stay away from gluten but it's difficult to enjoy simple meals like a refreshing sandwich with the gluten-free breads available. ( I was trying to eat a hot dog, but the Scharr bread was crumbling as I held it and gummy as I chewed.) Q: which bread has anyone found to be best for sandwiches and toast?

@Scott Adams @knitty kitty @cristiana @trents Thank you everyone, I should add, I forgot to mention, I did have an upper endoscopy around the time and that came back all clear/perfectly fine , so with both of those I always ruled out celiac disease , especially considering sometimes I'm absolutely fine with gluten

Something to thing about:- Coeliac Australia supported a study into Oat Toxicity in Coeliacs and found that oats triggered an immune response in eight percent of the 73 people who participated in the study. The study was published in the November 2024, Journal of Autoimmunity.