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My Past Celiac Test


mle-ii

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mle-ii Explorer

Ok, I know I'm gluten intollerant as found by enterolab and via going gluten free and having a significant reduction in symtoms. I just found a previous notation by the lab testing my GI Dr ordered and I'm wondering what exactly was tested. Obviously the test was negative, but I'm wonderint which test they ran. Thanks!

Here's what it said:

TEST NORM REFERNCE RANGE

ENDOMYSIAL NONE DET NONE DET

AB, IGA SCR

ENDOMYSIAL NOT DONE NONE DET

AB, IGA TITER

(NOTE)

Because the Endomysial Ab, IgA screen was negative,

the Endomysial Ab, IgA titer was not performed.

INTERPRETATION: Endomysial Ab, IgA

Endomysial antibodies are screened using an ELISA tissue

transglutaminase (tTG) assay. All samples which are

positive are titered by IFA. The endomysial antigen has

been identifed as the protein cross-linking enzyme known

as tissue transglutaminase.


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mle-ii Explorer

I'm guessing that this is the test.

Tissue Transglutaminase (tTG), IgA

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Use

Detection of antibodies to aid in the diagnosis of gluten-sensitive enteropathy (GSE), such as celiac disease and dermatitis herpetiformis

Limitations

A negative tTG IgA result in an untreated patient does not rule out gluten-sensitive enteropathy. This result can often be explained by selective IgA deficiency, a relatively frequent finding in celiac disease. Results of this assay should be used in conjunction with clinical findings and other serological tests.

Methodology

Enzyme immunoassay (EIA)

Additional Information

Studies have demonstrated that IgA endomysial antibody tests have >99% specificity for gluten-sensitive enteropathy.1 Recently, the endomysial antigen has been identified as the protein cross-linking enzyme known as tissue transglutaminase (tTG).2

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