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KarenLee

What Does This Mean?

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What does this part of the results mean?

HLA-DQB1 Molecular analysis, Allele 1 0301

HLA-DQB1 Molecular analysis, Allele 2 0603

Serologic equivalent: HLA-DQ 3,1 (Subtype 7,6)

I read the description, but still not sure. It says that I "do not posess the main genes predisposing to celiac sprue (HLA-DQ2 or HLA-DQ8), HLA gene analysis reveals that you have two copies of a gene that predisposes to gluten sensitivity (DQ1 or DQ3 not subtype 8)." So I do not have Celiac??

By the way, if it helps, here is the rest of the results:

Fecal Antigliadin IgA 36 (Normal Range <10 Units)

Fecal Antitissue Transglutaminase IgA 17 Units (Normal Range <10 Units)

Quantitative Microscopic Fecal Fat Score 73 Units (Normal Range <300 Units)

Fecal anti-casein (cow


Karen

Gluten Free since 10/22/06

Enterolab:

positive for gluten sensitivity

2 gluten sensitivity genes

positive casein sensitivity

Prometheus blood test-neg.

Hypothyroid

Osteopenia

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Celiac.com Sponsor (A8):

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enterolab does not test for celiac (other than the genetic tests), they test only for gluten intolerance. Of course the difference is basically semantics - the result is the same: you can't eat gluten. The genetic results you asked about say that you don't have the markers for celiac disease but you do have others that Dr. Fine has identified for gluten intolerance. That would theoretically mean that gluten would react very badly when ingested, but not actually damage your villi. Your results say, according to enterolab, you should avoid all gluten and casein. I know it sounds hard, but I'm doing it and have found it quite manageable.

If you have more questions, the Enterolab staff is very prompt with email replys.


Diagnosed through Enterolab (9.27.06)

Antigliadin IgA 164 (Normal Range <10 Units)

Antitissue Transglutaminase IgA 75 Units (Normal Range <10 Units)

Quantitative Microscopic Fat Score 874 Units (Normal Range <300 Units)

Fecal anti-casein (cow’s milk) IgA antibody 73 Units (Normal Range <10 Units)

HLA-DQ 2,1 (Subtype 2,5)

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