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Luisa2552

Confused With Gene Test Results

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I got my HLA DQ2 and DQ8 tests and I'm not sure what they mean. I do have an appt. with my GI doc. next week but I thought I'd ask here first.

Even though DQ2 and DQ8 were requested, the tests listed say HLA-DQB1 02 (DQ2)

HLA-DQB1 05 (DQ5)

Both have a * after them which indicates 'out of range'. There is no range given.

What is that ? I've waited 3 weeks for this?

I'm guessing I don't have either gene so it didn't register on their test??

Anyone else get results like this? These tests were blood tests pulled at a local lab and run by Quest Diagnostics in VA.

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Even though DQ2 and DQ8 were requested, the tests listed say HLA-DQB1 02 (DQ2)

HLA-DQB1 05 (DQ5)

It appears as though you have the DQ2 (a celiac gene) and DQ5 (a/k/a DQ1, subtype 5.) The DQ1 is not one of the main genes predisposing to celiac disease, but many here have it (or have 2.) Enterolab calls DQ1 a "gluten sensitivity" gene. There is no "range" for gene results. They just tell you which 2 copies you have, as above.

Rho

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Are you saying these were the results or the tests requested?

Those were the results. I've done a bunch of reading and I guess I have the DQ2 and DQ5. I know the DQ2 is for Celiac and I'm not sure what the DQ5 is about. Don't you have to have BOTH DQ2 and DQ8 to be celiac disease? It's all so confusing :(

And by the way, my total IgA was normal......

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No, you only need one and there are a small percentage that don't even need one. DQ2 is the more common one and just because you have it, doesn't mean that you have (or will get) Celiac Disease. It means you are genetically at risk - but so is about 39% of the population (based on my son's gene test).

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