Jump to content
This site uses cookies. Continued use is acceptance of our Terms of Use and Privacy Policy. More Info... ×

  • Welcome to Celiac.com!

    You have found your celiac tribe! Join us and ask questions in our forum, share your story, and connect with others.



  • Celiac.com Sponsor (A1):

    Celiac.com Sponsor (A1-M):

  • Get Celiac.com Updates:
    Support Celiac.com!
    eNewsletter
    Donate

Serotonin Levels

Sugar

By Sugar
in Related Issues & Disorders

Recommended Posts

Sugar Rookie
Sugar
Posted

Hello everyone. I was just wondering, does anyone know about the effect of celiac disease on seratonin levels? I know I've been addicted to wheat and sugar and also suffered from depression. I feel better since going gluten free, but I was just wondering because I know eating things your body rejects can give you a "high." Any thoughts?

Link to comment
Share on other sites
Celiac.com Sponsor (A8):
Celiac.com Sponsor (A8):

Celiac.com Sponsor (A8-M):


rock on Apprentice
rock on
Posted

I do think that having celiac or gluten sensitivities or even only leaky gut syndrome could potentially be a root cause of depression or low serotonin levels. I was actually just looking into how amino acids can help our bodies (because of someone here who mentioned taking l-glutamine to help heal a leaky gut) and came across this article. I thought it was very interesting...it talks about our brain needing certain chemicals & how we can turn to certain drugs, alcohol or even food if we are deficient in these chemicals. If your gut isn't healthy, you might not be getting all the nutrients you need from your food & therefore are lacking in essential amino & fatty acids.

Open Original Shared Link

Link to comment
Share on other sites
Sugar Rookie
Sugar
  • Author
Posted

Hey, thanks a lot for the info!

Link to comment
Share on other sites
ravenwoodglass Mentor
ravenwoodglass
Posted
Hello everyone. I was just wondering, does anyone know about the effect of celiac disease on seratonin levels? I know I've been addicted to wheat and sugar and also suffered from depression. I feel better since going gluten free, but I was just wondering because I know eating things your body rejects can give you a "high." Any thoughts?

I know that celiac related depression and anxiety issues abound but I am not so sure about their relation to serotonin levels. I suspect that it is a different mechanism that is causing it because of the seriously bad effects many of us have when given drugs like SSRI's and other psychotropics. For some of us the drugs effects on the serotonin levels can make us much worse and lead to suicidal ideation and behaviors like cutting and even actual psychotic episodes. In my family the seizure meds were most effective with depressive and anxiety issues, leading me to be diagnosed with a rare form of epilepsy. In other words it was the misfiring of electrical impulses that was causeing the problem not the serotonin levels. In myself this misfiring also lead to ataxia and progressive paralysis of my legs. All of those type of issues we had were gone when we had been gluten-free for a couple of months and only return when glutened.

Link to comment
Share on other sites
Sugar Rookie
Sugar
  • Author
Posted

That is fascinating! I'm glad you were able to figure it out for yourself. Thank you.

Link to comment
Share on other sites
celiacgirls Apprentice
celiacgirls
Posted

I think gluten was affecting my serotonin levels. I was taking an a/d and feeling better than I had ever felt in my whole life when I started the gluten-free diet. Within 2 days, I could tell the gluten-free diet was making me feel even better with mood/anxiety issues. But I also felt giddy and knew I needed to decrease my a/d. I think I had too much serotonin with the med and the diet. I tapered off the med as fast as I could and haven't needed it since. When I have been glutened, those problems come back.

Link to comment
Share on other sites
The One Apprentice
The One
Posted

I am not sure how but I do agree that anxiety/depression IS linked to Celiac. After going gluten free my anxiety improved a little, though I've had it for too long as for it to completely go away, I have noticed that when I get glutened [which happened quite a few times at the beginning of the diet] I would have panic attacks much more often.

Link to comment
Share on other sites
Celiac.com Sponsor (A8):
Celiac.com Sponsor (A8):

Celiac.com Sponsor (A8-M):


  • 1 month later...
UK Cat Newbie
UK Cat
Posted

Hi,

saw this online, and thought you might be interested. I'm a psychology student, with suspected coeliac disease, and a history of mood disorders, and thought i'd have a look into any correlations between serotonin levels and coeliac disease/other GI disorders. There is a large amount of serotonin activity in the gastro-intestinal tract- I think the amount of serotonin receptors in the gut are second only to the brain within the human body- hence looking into it. Anyway, found this journal article which suggests a link between mood disorders and gluten intolerance/coeliac in children and young people, copy and paste into your browser.

Open Original Shared Link

cheers

Cat

Link to comment
Share on other sites
  • 1 year later...
Sugar Rookie
Sugar
  • Author
Posted

Wow! I did not know that. Thanx very much for posting!

Link to comment
Share on other sites
one more mile Contributor
one more mile
Posted

battled depression my whole life. I tried shrinks and med and dark chocolate and they only worked so far.

It took a few weeks but I became uncomfortably happy when Gluten free. I even asked my doctor if I was getting manic.

He asked me a few questions and said you are not ill you are normal. Seems I had forgotten what normal is.

My whole emotional core has changed. I tend to wake up happy, and laugh at things rather then get mad.

one more mile

Link to comment
Share on other sites
larry mac Enthusiast
larry mac
Posted
..........

Open Original Shared Link

...........

This link is very appropriate, "Psychosomatic".

best regards, lm

Link to comment
Share on other sites

Archived

This topic is now archived and is closed to further replies.

Go to topic listing
  • Celiac.com Sponsor (A19):


  • Member Statistics

    • Total Members
      121,070
    • Most Online (within 30 mins)
      7,748
    TT24
    Newest Member
    TT24
    Joined
  • Celiac.com Sponsor (A20):

  • Forum Statistics

    • Total Topics
      120.3k
    • Total Posts
      1m
  • Celiac.com Sponsor (A22):



  • Celiac.com Sponsor (A21):


  • Upcoming Events

  • Posts

    • Fluka66
      Waiting for urgent referral.

      By Fluka66 · Posted

      Thank you again for your reply and comments which I have read carefully as I appreciate any input at this stage. I'm tending to listen to what my body wants me to do, having been in agony for many years any respite has been welcome and avoiding all wheat and lactose has thankfully brought this.  When in pain before I was seen by a number of gynacologists as I had 22 fibroids and had an operation 13 years ago to shrink them . However the pain remained and intensified to the point over the years where I began passing out. I was in and out of a&e during covid when waiting rooms where empty. My present diet is the only thing that's given me any hope for the future. As I say I had never heard of celiac disease before starting so I guess had this not come up in a conversation I would just have carried on. It was the swollen lymph node that sent me to a boots pharmacist who immediately sent me to a&e where a Dr asked questions prescribed antibiotics and then back to my GP. I'm now waiting for my hospital appointment . Hope this answers your question. I found out more about the disease because I googled something I wouldn't normally do, it did shed light on the disease but I also read some things that this disease can do. On good days I actually hope I haven't got this but on further investigation my mother's side of the family all Celtic have had various problems 're stomach pain my poor grandmother cried in pain as did her sister whilst two of her brother's survived WW2 but died from ulcers put down to stress of fighting.  Wishing you well with your recovery.  Many thanks  
    • knitty kitty
      14 year old with Celiac & EOE still suffering...

      By knitty kitty · Posted

      Welcome to the forum, @Nacina, What supplements is your son taking?
    • knitty kitty
      This forum might be the last hope I have in my life. Please I beg you

      By knitty kitty · Posted

      @BluegrassCeliac, I'm agreeing.  It's a good thing taking magnesium. And B vitamins. Magnesium and Thiamine work together.  If you supplement the B vitamins which include Thiamine, but don't have sufficient magnesium, Thiamine won't work well.  If you take Magnesium, but not Thiamine, magnesium won't work as well by itself. Hydrochlorothiazide HCTZ is a sulfonamide drug, a sulfa drug.  So are proton pump inhibitors PPIs, and SSRIs. High dose Thiamine is used to resolve cytokine storms.  High dose Thiamine was used in patients having cytokine storms in Covid infections.  Magnesium supplementation also improves cytokine storms, and was also used during Covid. How's your Vitamin D? References: Thiamine and magnesium deficiencies: keys to disease https://pubmed.ncbi.nlm.nih.gov/25542071/ Hiding in Plain Sight: Modern Thiamine Deficiency https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8533683/ The Effect of a High-Dose Vitamin B Multivitamin Supplement on the Relationship between Brain Metabolism and Blood Biomarkers of Oxidative Stress: A Randomized Control Trial https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6316433/ High‐dose Vitamin B6 supplementation reduces anxiety and strengthens visual surround suppression https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9787829/ Repurposing Treatment of Wernicke-Korsakoff Syndrome for Th-17 Cell Immune Storm Syndrome and Neurological Symptoms in COVID-19: Thiamine Efficacy and Safety, In-Vitro Evidence and Pharmacokinetic Profile https://pubmed.ncbi.nlm.nih.gov/33737877/ Higher Intake of Dietary Magnesium Is Inversely Associated With COVID-19 Severity and Symptoms in Hospitalized Patients: A Cross-Sectional Study https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9132593/ Magnesium and Vitamin D Deficiency as a Potential Cause of Immune Dysfunction, Cytokine Storm and Disseminated Intravascular Coagulation in covid-19 patients https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7861592/ Sulfonamide Hypersensitivity https://pubmed.ncbi.nlm.nih.gov/31495421/
    • BluegrassCeliac
      This forum might be the last hope I have in my life. Please I beg you

      By BluegrassCeliac · Posted

      Hi,   Not saying Thiamine (B1) couldn't be an issue as well, but Mg was definitely the cause of my problems. It's the only thing that worked. I supplemented with B vitamins, but that didn't change anything, in fact they made me sick. Mg stopped all my muscle pain (HCTZ) within a few months and fixed all the intestinal problems HCTZ caused as well. Mom has an allergy to some sulfa drugs (IgG Celiac too), but I don't think I've ever taken them. Mg boosted my energy as well. It solved a lot of problems. I take 1000mg MgO a day with no problems. I boost absorption with Vitamin D. Some people can't take MgO,  like mom, she takes Mg Glycinate. It's one of those things that someone has try and find the right form for themselves. Everyone's different. Mg deficiency can cause anxiety and is a treatment for it. A pharmacist gave me a list of drugs years ago that cause Mg deficiency: PPIs, H2 bockers, HCTZ, some beta blockers (metoprolol which I've taken -- horrible side effects), some anti-anxiety meds too were on it. I posted because I saw he was an IgG celiac. He's the first one I've seen in 20 years, other than my family. We're rare. All the celiacs I've met are IgA. Finding healthcare is a nightmare. Just trying to help. B  
    • Scott Adams
      14 year old with Celiac & EOE still suffering...

      By Scott Adams · Posted

      It sounds like you've been through a lot with your son's health journey, and it's understandable that you're seeking answers and solutions. Given the complexity of his symptoms and medical history, it might be beneficial to explore a few avenues: Encourage your son to keep a detailed journal of his symptoms, including when they occur, their severity, any triggers or patterns, and how they impact his daily life. This information can be valuable during medical consultations and may help identify correlations or trends. Consider seeking opinions from specialized medical centers or academic hospitals that have multidisciplinary teams specializing in gastrointestinal disorders, especially those related to Celiac disease and Eosinophilic Esophagitis (EOE). These centers often have experts who deal with complex cases and can offer a comprehensive evaluation. Since you've already explored alternative medicine with a nutrition response doctor and a gut detox diet, you may want to consider consulting a functional medicine practitioner. They take a holistic approach to health, looking at underlying causes and imbalances that may contribute to symptoms. Given his low vitamin D levels and other nutritional markers, a thorough nutritional assessment by a registered dietitian or nutritionist specializing in gastrointestinal health could provide insights into any deficiencies or dietary adjustments that might help alleviate symptoms. In addition to routine tests, consider asking about more specialized tests that may not be part of standard screenings. These could include comprehensive stool analyses, food intolerance testing, allergy panels, or advanced imaging studies to assess gut health.
×
×
  • Create New...