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kevieb

Gene Test Results

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it has been such a long time since i have been on the board that i don't know if anyone will even remember me. the look of the board has changed since i was last here.

we joined the celiac study that is being done at the university of california, irvine a year and a half ago. the results of the celiac tests confirmed what we already knew about our three girls with celiac. i just barely found out the results of our genetic testing. i didn't get the results of my two older kids because they are over 18. i asked them to mail them the results. as far as the rest of us---every single one of us carries the DQ2 gene----both my husband and i and all 7 kids we have had together. my two oldest are from my first marriage. kevin has two from another marriage, also, but neither one of them was tested.

i really didn't expect that every one of us would carry one of the genes and i wonder what activated the disease in the three girls and not in the rest of us. i guess this means yearly blood tests for all of us.

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I have a post about my test results, which the only thing I am sure of is that I have the DQ2 gene; I don't know what the antibody results show if anything. I haven't really got a good answer on what the positive DQ2 means, can you help me out?

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It means you have the genetic disposition to develop celiac, but it doesn't mean that you necessarily will develop it. Some people do, some don't and as far as I know, the reason isn't really known yet. Often people get sick after a major trauma or stress of some sort, like an operation, or having mono, or pregnancy, but what exactly triggers the celiac I don't know.

Pauliina

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ducky is right---the lady over the study says that they know there are other genes involved besides DQ2 and DQ8. they are trying to find out what they are. a good example of this would be the fact that with identical twins, if one has celiac the other has a 70-75% chance of getting celiac---but not a 100% chance. in our case, my identical twins both have celiac.

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